Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.437 0.212 0.525 55.0 -9999.0 0.0 55.0 KIRREL -0.092 0.137 -9999.0 0.0 -0.691 3.0 3.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.438 0.213 -9999.0 0.0 -0.526 55.0 55.0 PLCG1 0.022 0.004 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.029 0.026 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.021 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.436 0.256 -9999.0 0.0 -0.511 57.0 57.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.385 0.224 -9999.0 0.0 -0.457 55.0 55.0 FYN -0.417 0.229 -9999.0 0.0 -0.481 57.0 57.0 mol:Ca2+ -0.432 0.251 -9999.0 0.0 -0.506 57.0 57.0 mol:DAG -0.435 0.253 -9999.0 0.0 -0.509 57.0 57.0 NPHS2 -0.296 0.307 -9999.0 0.0 -0.688 25.0 25.0 mol:IP3 -0.435 0.253 -9999.0 0.0 -0.509 57.0 57.0 regulation of endocytosis -0.387 0.231 -9999.0 0.0 -0.454 57.0 57.0 Nephrin/NEPH1/podocin/Cholesterol -0.435 0.252 -9999.0 0.0 -0.509 57.0 57.0 establishment of cell polarity -0.437 0.212 -9999.0 0.0 -0.525 55.0 55.0 Nephrin/NEPH1/podocin/NCK1-2 -0.407 0.245 -9999.0 0.0 -0.479 57.0 57.0 Nephrin/NEPH1/beta Arrestin2 -0.393 0.236 -9999.0 0.0 -0.461 57.0 57.0 NPHS1 -0.544 0.247 -9999.0 0.0 -0.66 54.0 54.0 Nephrin/NEPH1/podocin -0.414 0.241 -9999.0 0.0 -0.484 57.0 57.0 TJP1 0.022 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.022 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.023 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.437 0.255 -9999.0 0.0 -0.512 57.0 57.0 CD2AP 0.022 0.005 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.436 0.256 -9999.0 0.0 -0.511 57.0 57.0 GRB2 0.022 0.005 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.405 0.223 -9999.0 0.0 -0.472 56.0 56.0 cytoskeleton organization -0.479 0.258 -9999.0 0.0 -0.564 55.0 55.0 Nephrin/NEPH1 -0.319 0.161 -9999.0 0.0 -0.384 55.0 55.0 Nephrin/NEPH1/ZO-1 -0.353 0.179 -9999.0 0.0 -0.427 55.0 55.0