Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.394 0.231 0.526 350.0 -9999.0 0.0 350.0 KIRREL -0.053 0.057 -9999.0 0.0 -0.509 3.0 3.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.395 0.231 -9999.0 0.0 -0.527 350.0 350.0 PLCG1 0.028 0.006 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.027 0.034 -9999.0 0.0 -0.707 1.0 1.0 WASL 0.026 0.009 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.416 0.281 -9999.0 0.0 -0.545 361.0 361.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.339 0.232 -9999.0 0.0 -0.567 203.0 203.0 FYN -0.399 0.256 0.264 1.0 -0.508 373.0 374.0 mol:Ca2+ -0.408 0.277 -9999.0 0.0 -0.536 363.0 363.0 mol:DAG -0.41 0.279 -9999.0 0.0 -0.539 363.0 363.0 NPHS2 -0.341 0.329 -9999.0 0.0 -0.692 219.0 219.0 mol:IP3 -0.41 0.279 -9999.0 0.0 -0.539 363.0 363.0 regulation of endocytosis -0.372 0.25 -9999.0 0.0 -0.503 328.0 328.0 Nephrin/NEPH1/podocin/Cholesterol -0.422 0.277 -9999.0 0.0 -0.542 373.0 373.0 establishment of cell polarity -0.394 0.231 -9999.0 0.0 -0.526 350.0 350.0 Nephrin/NEPH1/podocin/NCK1-2 -0.379 0.269 -9999.0 0.0 -0.649 195.0 195.0 Nephrin/NEPH1/beta Arrestin2 -0.377 0.255 -9999.0 0.0 -0.511 328.0 328.0 NPHS1 -0.517 0.285 -9999.0 0.0 -0.67 365.0 365.0 Nephrin/NEPH1/podocin -0.398 0.265 -9999.0 0.0 -0.512 373.0 373.0 TJP1 0.029 0.003 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.028 0.006 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.029 0.005 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.413 0.281 -9999.0 0.0 -0.542 363.0 363.0 CD2AP 0.028 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.414 0.281 -9999.0 0.0 -0.542 365.0 365.0 GRB2 0.029 0.005 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.391 0.256 0.276 1.0 -0.503 367.0 368.0 cytoskeleton organization -0.431 0.285 -9999.0 0.0 -0.593 317.0 317.0 Nephrin/NEPH1 -0.287 0.172 -9999.0 0.0 -0.385 350.0 350.0 Nephrin/NEPH1/ZO-1 -0.315 0.198 -9999.0 0.0 -0.429 349.0 349.0