Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.6 0.377 0.83 54.0 -9999.0 0.0 54.0 KIRREL -0.085 0.162 -9999.0 0.0 -1.044 2.0 2.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.602 0.378 -9999.0 0.0 -0.832 54.0 54.0 PLCG1 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.734 0.444 -9999.0 0.0 -0.899 62.0 62.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.526 0.344 -9999.0 0.0 -0.651 62.0 62.0 FYN -0.689 0.423 -9999.0 0.0 -0.849 62.0 62.0 mol:Ca2+ -0.718 0.43 -9999.0 0.0 -0.88 62.0 62.0 mol:DAG -0.726 0.436 -9999.0 0.0 -0.889 62.0 62.0 NPHS2 -0.576 0.477 -9999.0 0.0 -1.004 42.0 42.0 mol:IP3 -0.726 0.436 -9999.0 0.0 -0.889 62.0 62.0 regulation of endocytosis -0.649 0.392 -9999.0 0.0 -0.796 62.0 62.0 Nephrin/NEPH1/podocin/Cholesterol -0.739 0.446 -9999.0 0.0 -0.906 62.0 62.0 establishment of cell polarity -0.6 0.377 -9999.0 0.0 -0.83 54.0 54.0 Nephrin/NEPH1/podocin/NCK1-2 -0.688 0.422 -9999.0 0.0 -0.844 62.0 62.0 Nephrin/NEPH1/beta Arrestin2 -0.668 0.408 -9999.0 0.0 -0.818 62.0 62.0 NPHS1 -0.71 0.439 -9999.0 0.0 -0.989 54.0 54.0 Nephrin/NEPH1/podocin -0.701 0.426 -9999.0 0.0 -0.86 62.0 62.0 TJP1 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.734 0.444 -9999.0 0.0 -0.899 62.0 62.0 CD2AP 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.734 0.444 -9999.0 0.0 -0.899 62.0 62.0 GRB2 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.777 0.443 -9999.0 0.0 -0.912 65.0 65.0 cytoskeleton organization -0.715 0.449 -9999.0 0.0 -0.884 62.0 62.0 Nephrin/NEPH1 -0.47 0.303 -9999.0 0.0 -0.652 54.0 54.0 Nephrin/NEPH1/ZO-1 -0.508 0.327 -9999.0 0.0 -0.705 54.0 54.0