Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.393 0.265 0.547 54.0 -9999.0 0.0 54.0 KIRREL -0.084 0.12 -9999.0 0.0 -0.747 2.0 2.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.394 0.265 -9999.0 0.0 -0.548 54.0 54.0 PLCG1 0.025 0.007 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.024 0.008 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.022 0.011 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.444 0.313 -9999.0 0.0 -0.592 58.0 58.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.374 0.273 -9999.0 0.0 -0.525 52.0 52.0 FYN -0.436 0.274 -9999.0 0.0 -0.56 58.0 58.0 mol:Ca2+ -0.437 0.308 -9999.0 0.0 -0.592 56.0 56.0 mol:DAG -0.439 0.311 -9999.0 0.0 -0.596 56.0 56.0 NPHS2 -0.395 0.332 -9999.0 0.0 -0.709 40.0 40.0 mol:IP3 -0.439 0.311 -9999.0 0.0 -0.596 56.0 56.0 regulation of endocytosis -0.399 0.277 -9999.0 0.0 -0.532 57.0 57.0 Nephrin/NEPH1/podocin/Cholesterol -0.448 0.306 -9999.0 0.0 -0.584 59.0 59.0 establishment of cell polarity -0.393 0.265 -9999.0 0.0 -0.547 54.0 54.0 Nephrin/NEPH1/podocin/NCK1-2 -0.418 0.301 -9999.0 0.0 -0.565 57.0 57.0 Nephrin/NEPH1/beta Arrestin2 -0.405 0.283 -9999.0 0.0 -0.541 57.0 57.0 NPHS1 -0.498 0.301 -9999.0 0.0 -0.686 54.0 54.0 Nephrin/NEPH1/podocin -0.428 0.293 -9999.0 0.0 -0.564 58.0 58.0 TJP1 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.026 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.026 0.005 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.442 0.313 -9999.0 0.0 -0.6 56.0 56.0 CD2AP 0.024 0.008 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.44 0.311 -9999.0 0.0 -0.597 56.0 56.0 GRB2 0.024 0.009 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.486 0.29 -9999.0 0.0 -0.598 61.0 61.0 cytoskeleton organization -0.465 0.324 -9999.0 0.0 -0.642 53.0 53.0 Nephrin/NEPH1 -0.289 0.202 -9999.0 0.0 -0.404 54.0 54.0 Nephrin/NEPH1/ZO-1 -0.324 0.23 -9999.0 0.0 -0.462 53.0 53.0