Clinical Features CN_CNMF METHLYATION_CNMF MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL nMutated (%) nWild-Type Chi-square test_P Chi-square test_Q Chi-square test_P Chi-square test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q DNMT3A 51 (26%) 145 0.97745 1 3.9995e-07 1.48e-05 0.012187 0.329 0.19478 1 0.00083669 0.0259 3.9379e-06 0.000138 U2AF1 8 (4%) 188 0.77595 1 0.12829 1 0.23192 1 0.42592 1 0.07158 1 0.23373 1 FLT3 56 (29%) 140 0.015223 0.39 2.4831e-05 0.000844 1.8625e-07 7.08e-06 0.02093 0.502 0.00047063 0.0151 4.2239e-05 0.00139 IDH2 20 (10%) 176 0.27391 1 1.5933e-06 5.74e-05 0.72548 1 1 1 0.73947 1 0.59944 1 IDH1 19 (10%) 177 0.96878 1 0.005628 0.163 0.42274 1 0.26799 1 0.28417 1 0.43602 1 NPM1 54 (28%) 142 0.00085226 0.0259 3.2575e-20 1.34e-18 1.7916e-13 6.99e-12 0.0064878 0.182 6.5768e-14 2.63e-12 1.0737e-22 4.51e-21 NRAS 15 (8%) 181 0.015005 0.39 0.89186 1 0.64501 1 0.53908 1 0.82461 1 0.76509 1