num gene desc n mindist nmuts0 nmuts3 nmuts12 npairs0 npairs3 npairs12 337 DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 57 0 408 410 427 408 410 427 535 IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 19 0 171 171 171 171 171 171 536 IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 20 0 139 139 139 139 139 139 429 FLT3 fms-related tyrosine kinase 3 55 0 120 120 136 120 120 136 752 NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 15 0 31 51 51 31 51 51 955 RUNX1 runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) 20 0 16 21 26 16 21 26 589 KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 9 0 10 10 10 10 10 10 598 KRAS v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 8 0 3 7 7 3 7 7 902 PTPN11 protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) 9 0 1 3 10 1 3 10 1109 TET2 tet oncogene family member 2 21 0 1 1 2 1 1 2 925 RBBP4 retinoblastoma binding protein 4 2 0 1 1 1 1 1 1 198 CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 2 1 0 1 1 0 1 1 1033 SMC3 structural maintenance of chromosomes 3 7 1 0 1 1 0 1 1 1138 TP53 tumor protein p53 18 2 0 2 3 0 2 3 494 GSTK1 glutathione S-transferase kappa 1 2 2 0 1 1 0 1 1 986 SETBP1 SET binding protein 1 2 2 0 1 1 0 1 1 1032 SMC1A structural maintenance of chromosomes 1A 7 3 0 1 1 0 1 1 1221 WT1 Wilms tumor 1 12 3 0 1 1 0 1 1 692 MTA2 metastasis associated 1 family, member 2 2 6 0 0 1 0 0 1 179 CADM2 cell adhesion molecule 2 2 8 0 0 1 0 0 1 394 FAM154B family with sequence similarity 154, member B 2 10 0 0 1 0 0 1 403 FAM5C family with sequence similarity 5, member C 6 10 0 0 1 0 0 1 1155 TRPM3 transient receptor potential cation channel, subfamily M, member 3 2 12 0 0 1 0 0 1 1036 SMG1 smg-1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans) 3 13 0 0 0 0 0 0 276 CROCC ciliary rootlet coiled-coil, rootletin 3 15 0 0 0 0 0 0 60 APOB apolipoprotein B (including Ag(x) antigen) 2 16 0 0 0 0 0 0 322 DIS3 DIS3 mitotic control homolog (S. cerevisiae) 3 26 0 0 0 0 0 0 453 GBP4 guanylate binding protein 4 3 27 0 0 0 0 0 0 417 FCGBP Fc fragment of IgG binding protein 3 28 0 0 0 0 0 0 729 NF1 neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease) 2 30 0 0 0 0 0 0 1097 TCEAL6 transcription elongation factor A (SII)-like 6 2 30 0 0 0 0 0 0 308 DCLK1 doublecortin-like kinase 1 2 34 0 0 0 0 0 0 176 CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 2 36 0 0 0 0 0 0 390 EZH2 enhancer of zeste homolog 2 (Drosophila) 3 42 0 0 0 0 0 0 492 GRM8 glutamate receptor, metabotropic 8 2 43 0 0 0 0 0 0 919 RAD21 RAD21 homolog (S. pombe) 5 43 0 0 0 0 0 0 842 PHF6 PHD finger protein 6 6 45 0 0 0 0 0 0 1063 STAG2 stromal antigen 2 6 46 0 0 0 0 0 0 1168 TUBA3C tubulin, alpha 3c 2 47 0 0 0 0 0 0 830 PDCD2L programmed cell death 2-like 2 50 0 0 0 0 0 0 996 SI sucrase-isomaltase (alpha-glucosidase) 2 50 0 0 0 0 0 0 487 GRID1 glutamate receptor, ionotropic, delta 1 2 52 0 0 0 0 0 0 750 NR2E1 nuclear receptor subfamily 2, group E, member 1 2 52 0 0 0 0 0 0 969 SCN1A sodium channel, voltage-gated, type I, alpha subunit 2 52 0 0 0 0 0 0 886 PRAMEF2 PRAME family member 2 2 56 0 0 0 0 0 0 1081 SUZ12 suppressor of zeste 12 homolog (Drosophila) 3 60 0 0 0 0 0 0 341 DOCK2 dedicator of cytokinesis 2 2 65 0 0 0 0 0 0 399 FAM40B family with sequence similarity 40, member B 2 67 0 0 0 0 0 0 1227 ZBTB33 zinc finger and BTB domain containing 33 2 67 0 0 0 0 0 0 311 DDR2 discoidin domain receptor tyrosine kinase 2 2 69 0 0 0 0 0 0 462 GJB3 gap junction protein, beta 3, 31kDa 2 73 0 0 0 0 0 0 450 GATA2 GATA binding protein 2 2 81 0 0 0 0 0 0 739 NMUR2 neuromedin U receptor 2 2 99 0 0 0 0 0 0 286 CUL1 cullin 1 2 100 0 0 0 0 0 0 402 FAM57B family with sequence similarity 57, member B 2 103 0 0 0 0 0 0 857 PLCE1 phospholipase C, epsilon 1 4 108 0 0 0 0 0 0 274 CRISPLD1 cysteine-rich secretory protein LCCL domain containing 1 2 110 0 0 0 0 0 0 1114 THRAP3 thyroid hormone receptor associated protein 3 2 114 0 0 0 0 0 0 315 DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 2 115 0 0 0 0 0 0 1134 TNC tenascin C (hexabrachion) 2 120 0 0 0 0 0 0 1137 TOP3B topoisomerase (DNA) III beta 2 120 0 0 0 0 0 0 361 EED embryonic ectoderm development 2 121 0 0 0 0 0 0 698 MUC5B mucin 5B, oligomeric mucus/gel-forming 3 122 0 0 0 0 0 0 667 MEFV Mediterranean fever 2 128 0 0 0 0 0 0 436 FRYL FRY-like 2 133 0 0 0 0 0 0 137 C10orf28 chromosome 10 open reading frame 28 2 142 0 0 0 0 0 0 172 CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 3 143 0 0 0 0 0 0 862 PLEKHH1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1 2 145 0 0 0 0 0 0 81 ASXL1 additional sex combs like 1 (Drosophila) 5 159 0 0 0 0 0 0 1229 ZC3H18 zinc finger CCCH-type containing 18 2 161 0 0 0 0 0 0 1262 ZNF687 zinc finger protein 687 2 191 0 0 0 0 0 0 145 C17orf97 chromosome 17 open reading frame 97 2 192 0 0 0 0 0 0 216 CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 2 196 0 0 0 0 0 0 234 CHD4 chromodomain helicase DNA binding protein 4 2 198 0 0 0 0 0 0 908 PTPRT protein tyrosine phosphatase, receptor type, T 3 201 0 0 0 0 0 0 769 OR11H12 olfactory receptor, family 11, subfamily H, member 12 2 209 0 0 0 0 0 0 279 CSMD3 CUB and Sushi multiple domains 3 2 225 0 0 0 0 0 0 491 GRM3 glutamate receptor, metabotropic 3 2 225 0 0 0 0 0 0 547 ILDR1 immunoglobulin-like domain containing receptor 1 2 225 0 0 0 0 0 0 802 P2RY2 purinergic receptor P2Y, G-protein coupled, 2 2 228 0 0 0 0 0 0 358 E2F8 E2F transcription factor 8 2 234 0 0 0 0 0 0 447 GALNTL4 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 4 2 242 0 0 0 0 0 0 332 DNAH9 dynein, axonemal, heavy chain 9 3 245 0 0 0 0 0 0 979 SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 2 247 0 0 0 0 0 0 181 CADPS Ca2+-dependent secretion activator 2 258 0 0 0 0 0 0 278 CSMD1 CUB and Sushi multiple domains 1 4 262 0 0 0 0 0 0 588 KIF2B kinesin family member 2B 2 263 0 0 0 0 0 0 881 PPP1R3A protein phosphatase 1, regulatory (inhibitor) subunit 3A 2 265 0 0 0 0 0 0 942 RNF213 ring finger protein 213 2 277 0 0 0 0 0 0 770 OR13H1 olfactory receptor, family 13, subfamily H, member 1 2 283 0 0 0 0 0 0 578 KDM6A lysine (K)-specific demethylase 6A 3 288 0 0 0 0 0 0 563 KCNA4 potassium voltage-gated channel, shaker-related subfamily, member 4 2 291 0 0 0 0 0 0 1162 TTBK1 tau tubulin kinase 1 2 298 0 0 0 0 0 0 581 KIAA0240 KIAA0240 2 311 0 0 0 0 0 0 510 HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 2 313 0 0 0 0 0 0 1181 UNC5B unc-5 homolog B (C. elegans) 2 313 0 0 0 0 0 0 695 MTUS2 microtubule associated tumor suppressor candidate 2 2 348 0 0 0 0 0 0 848 PKD1L2 polycystic kidney disease 1-like 2 2 382 0 0 0 0 0 0 650 MAP2 microtubule-associated protein 2 2 384 0 0 0 0 0 0 1051 SPEN spen homolog, transcriptional regulator (Drosophila) 3 384 0 0 0 0 0 0 173 CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit 3 386 0 0 0 0 0 0 899 PSME4 proteasome (prosome, macropain) activator subunit 4 2 409 0 0 0 0 0 0 424 FLG filaggrin 2 420 0 0 0 0 0 0 252 CNTN5 contactin 5 2 489 0 0 0 0 0 0 366 EGFR epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) 2 503 0 0 0 0 0 0 694 MTMR8 myotubularin related protein 8 2 506 0 0 0 0 0 0 254 CNTNAP4 contactin associated protein-like 4 2 517 0 0 0 0 0 0 490 GRIK4 glutamate receptor, ionotropic, kainate 4 2 529 0 0 0 0 0 0 121 BMPER BMP binding endothelial regulator 2 600 0 0 0 0 0 0 17 ADAM11 ADAM metallopeptidase domain 11 2 645 0 0 0 0 0 0 225 CECR2 cat eye syndrome chromosome region, candidate 2 2 657 0 0 0 0 0 0 664 MED12 mediator complex subunit 12 2 727 0 0 0 0 0 0 579 KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 2 777 0 0 0 0 0 0 1108 TET1 tet oncogene 1 2 790 0 0 0 0 0 0 404 FAM65A family with sequence similarity 65, member A 2 814 0 0 0 0 0 0 938 RIMS1 regulating synaptic membrane exocytosis 1 2 818 0 0 0 0 0 0 575 KCNU1 potassium channel, subfamily U, member 1 2 850 0 0 0 0 0 0 757 NRXN3 neurexin 3 2 863 0 0 0 0 0 0 958 RYR3 ryanodine receptor 3 2 964 0 0 0 0 0 0 323 DLC1 deleted in liver cancer 1 2 1032 0 0 0 0 0 0 87 ATP10B ATPase, class V, type 10B 2 1042 0 0 0 0 0 0 894 PRPF8 PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae) 2 1063 0 0 0 0 0 0 696 MUC16 mucin 16, cell surface associated 3 1127 0 0 0 0 0 0 257 COL12A1 collagen, type XII, alpha 1 3 1267 0 0 0 0 0 0 1166 TTN titin 7 1376 0 0 0 0 0 0 474 GPR112 G protein-coupled receptor 112 2 1466 0 0 0 0 0 0 307 DCHS2 dachsous 2 (Drosophila) 2 1939 0 0 0 0 0 0 246 CMYA5 cardiomyopathy associated 5 2 2253 0 0 0 0 0 0 130 BSN bassoon (presynaptic cytomatrix protein) 2 3017 0 0 0 0 0 0 851 PKHD1L1 polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1 2 3400 0 0 0 0 0 0