Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	0.119	0.276	0.542	16.0	-0.634	2.0	18.0
IHH	0.073	0.144	0.347	6.0	-0.359	3.0	9.0
SHH Np/Cholesterol/GAS1	-0.056	0.157	-9999.0	0.0	-0.418	9.0	9.0
LRPAP1	0.024	0.004	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	0.056	0.156	0.415	9.0	-9999.0	0.0	9.0
SMO/beta Arrestin2	0.058	0.186	0.441	2.0	-0.679	2.0	4.0
SMO	0.052	0.203	0.455	3.0	-0.616	3.0	6.0
AKT1	0.046	0.134	0.327	2.0	-0.374	1.0	3.0
ARRB2	0.02	0.01	-9999.0	0.0	-9999.0	0.0	0.0
BOC	0.025	0.0	-9999.0	0.0	-9999.0	0.0	0.0
ADRBK1	0.024	0.003	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	0.053	0.201	0.453	3.0	-0.605	3.0	6.0
STIL	0.087	0.207	0.513	6.0	-0.562	2.0	8.0
DHH N/PTCH2	0.034	0.009	-9999.0	0.0	-9999.0	0.0	0.0
DHH N/PTCH1	0.08	0.194	0.484	3.0	-0.547	3.0	6.0
PIK3CA	0.025	0.0	-9999.0	0.0	-9999.0	0.0	0.0
DHH	0.024	0.002	-9999.0	0.0	-9999.0	0.0	0.0
PTHLH	0.133	0.313	0.626	16.0	-0.706	2.0	18.0
determination of left/right symmetry	0.053	0.201	0.453	3.0	-0.605	3.0	6.0
PIK3R1	0.024	0.004	-9999.0	0.0	-9999.0	0.0	0.0
skeletal system development	0.133	0.312	0.625	16.0	-0.699	2.0	18.0
IHH N/Hhip	-0.243	0.305	-9999.0	0.0	-0.517	37.0	37.0
DHH N/Hhip	-0.239	0.255	-9999.0	0.0	-0.474	37.0	37.0
mol:Cholesterol	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	0.053	0.201	0.453	3.0	-0.605	3.0	6.0
pancreas development	-0.328	0.327	-9999.0	0.0	-0.63	37.0	37.0
HHAT	0.019	0.01	-9999.0	0.0	-9999.0	0.0	0.0
PI3K	0.036	0.006	-9999.0	0.0	-9999.0	0.0	0.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	-0.087	0.244	-9999.0	0.0	-0.614	12.0	12.0
somite specification	0.053	0.201	0.453	3.0	-0.605	3.0	6.0
SHH Np/Cholesterol/PTCH1	0.043	0.176	0.43	2.0	-0.503	3.0	5.0
SHH Np/Cholesterol/PTCH2	0.001	0.075	-9999.0	0.0	-0.287	4.0	4.0
SHH Np/Cholesterol/Megalin	-0.071	0.17	0.228	2.0	-0.34	18.0	20.0
SHH	0.003	0.093	0.264	2.0	-0.474	2.0	4.0
catabolic process	0.09	0.234	0.424	16.0	-0.598	3.0	19.0
SMO/Vitamin D3	0.078	0.217	0.565	3.0	-0.659	2.0	5.0
SHH Np/Cholesterol/Hhip	-0.184	0.199	-9999.0	0.0	-0.392	30.0	30.0
LRP2	-0.11	0.285	0.374	2.0	-0.639	15.0	17.0
receptor-mediated endocytosis	-0.021	0.223	0.412	1.0	-0.577	5.0	6.0
SHH Np/Cholesterol/BOC	0.002	0.075	-9999.0	0.0	-0.287	4.0	4.0
SHH Np/Cholesterol/CDO	0.001	0.074	-9999.0	0.0	-0.369	2.0	2.0
mesenchymal cell differentiation	0.183	0.198	0.389	30.0	-9999.0	0.0	30.0
mol:Vitamin D3	0.088	0.207	0.559	3.0	-0.504	3.0	6.0
IHH N/PTCH2	0.055	0.096	-9999.0	0.0	-0.318	2.0	2.0
CDON	0.024	0.005	-9999.0	0.0	-9999.0	0.0	0.0
IHH N/PTCH1	0.104	0.243	0.452	16.0	-0.602	3.0	19.0
Megalin/LRPAP1	-0.071	0.22	0.266	2.0	-0.481	15.0	17.0
PTCH2	0.023	0.006	-9999.0	0.0	-9999.0	0.0	0.0
SHH Np/Cholesterol	-0.005	0.073	-9999.0	0.0	-0.373	2.0	2.0
PTCH1	0.09	0.235	0.424	16.0	-0.601	3.0	19.0
HHIP	-0.328	0.327	-9999.0	0.0	-0.631	37.0	37.0