Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.031 0.101 0.361 34.0 -9999.0 0.0 34.0 KIRREL -0.005 0.081 -9999.0 0.0 -0.504 10.0 10.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.031 0.102 -9999.0 0.0 -0.361 34.0 34.0 PLCG1 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.022 0.071 -9999.0 0.0 -9999.0 0.0 0.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.01 0.052 -9999.0 0.0 -0.235 9.0 9.0 FYN -0.005 0.069 -9999.0 0.0 -0.245 10.0 10.0 mol:Ca2+ -0.022 0.071 -9999.0 0.0 -0.259 2.0 2.0 mol:DAG -0.022 0.071 -9999.0 0.0 -0.26 2.0 2.0 NPHS2 -0.001 0.014 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.022 0.071 -9999.0 0.0 -0.26 2.0 2.0 regulation of endocytosis -0.018 0.059 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/Cholesterol -0.023 0.073 -9999.0 0.0 -0.26 34.0 34.0 establishment of cell polarity -0.031 0.101 -9999.0 0.0 -0.361 34.0 34.0 Nephrin/NEPH1/podocin/NCK1-2 -0.019 0.063 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/beta Arrestin2 -0.019 0.059 -9999.0 0.0 -9999.0 0.0 0.0 NPHS1 -0.025 0.125 -9999.0 0.0 -0.512 24.0 24.0 Nephrin/NEPH1/podocin -0.02 0.065 -9999.0 0.0 -0.246 10.0 10.0 TJP1 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.022 0.071 -9999.0 0.0 -0.261 2.0 2.0 CD2AP 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.022 0.071 -9999.0 0.0 -0.261 2.0 2.0 GRB2 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.022 0.099 -9999.0 0.0 -0.282 27.0 27.0 cytoskeleton organization 0.013 0.061 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1 -0.022 0.071 -9999.0 0.0 -0.251 34.0 34.0 Nephrin/NEPH1/ZO-1 -0.024 0.078 -9999.0 0.0 -0.278 34.0 34.0