Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	-0.09	0.188	0.325	6.0	-0.502	36.0	42.0
IHH	-0.013	0.128	0.294	6.0	-0.381	34.0	40.0
SHH Np/Cholesterol/GAS1	-0.036	0.057	0.115	1.0	-0.183	49.0	50.0
LRPAP1	0.021	0.004	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	0.036	0.057	0.182	49.0	-0.114	1.0	50.0
SMO/beta Arrestin2	-0.143	0.183	0.32	1.0	-0.33	145.0	146.0
SMO	-0.144	0.188	0.345	1.0	-0.338	154.0	155.0
AKT1	-0.079	0.145	0.266	1.0	-0.493	26.0	27.0
ARRB2	0.019	0.006	-9999.0	0.0	-9999.0	0.0	0.0
BOC	0.02	0.018	-9999.0	0.0	-0.328	1.0	1.0
ADRBK1	0.021	0.004	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	-0.142	0.186	0.344	1.0	-0.334	154.0	155.0
STIL	-0.082	0.144	0.265	9.0	-0.313	52.0	61.0
DHH N/PTCH2	0.013	0.066	-9999.0	0.0	-0.23	27.0	27.0
DHH N/PTCH1	-0.105	0.155	-9999.0	0.0	-0.24	183.0	183.0
PIK3CA	0.02	0.004	-9999.0	0.0	-9999.0	0.0	0.0
DHH	-0.002	0.087	-9999.0	0.0	-0.328	26.0	26.0
PTHLH	-0.119	0.227	0.39	6.0	-0.559	34.0	40.0
determination of left/right symmetry	-0.142	0.186	0.344	1.0	-0.334	154.0	155.0
PIK3R1	0.02	0.005	-9999.0	0.0	-9999.0	0.0	0.0
skeletal system development	-0.118	0.226	0.39	6.0	-0.555	34.0	40.0
IHH N/Hhip	-0.221	0.179	0.211	3.0	-0.315	288.0	291.0
DHH N/Hhip	-0.121	0.143	-9999.0	0.0	-0.247	213.0	213.0
mol:Cholesterol	-0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	-0.142	0.186	0.344	1.0	-0.334	154.0	155.0
pancreas development	-0.165	0.173	-9999.0	0.0	-0.327	209.0	209.0
HHAT	0.018	0.025	-9999.0	0.0	-0.328	2.0	2.0
PI3K	0.029	0.009	-9999.0	0.0	-9999.0	0.0	0.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	0.012	0.055	-9999.0	0.0	-0.328	10.0	10.0
somite specification	-0.142	0.186	0.344	1.0	-0.334	154.0	155.0
SHH Np/Cholesterol/PTCH1	-0.101	0.135	0.177	2.0	-0.331	54.0	56.0
SHH Np/Cholesterol/PTCH2	-0.033	0.052	0.115	1.0	-0.177	44.0	45.0
SHH Np/Cholesterol/Megalin	-0.068	0.087	0.115	1.0	-0.195	115.0	116.0
SHH	-0.039	0.069	0.156	1.0	-0.232	44.0	45.0
catabolic process	-0.105	0.164	0.234	3.0	-0.254	184.0	187.0
SMO/Vitamin D3	-0.118	0.174	0.371	2.0	-0.402	51.0	53.0
SHH Np/Cholesterol/Hhip	-0.105	0.1	0.115	1.0	-0.198	195.0	196.0
LRP2	-0.072	0.156	0.331	1.0	-0.328	105.0	106.0
receptor-mediated endocytosis	-0.164	0.185	0.304	2.0	-0.408	101.0	103.0
SHH Np/Cholesterol/BOC	-0.033	0.052	0.115	1.0	-0.177	43.0	44.0
SHH Np/Cholesterol/CDO	-0.034	0.056	0.115	1.0	-0.184	45.0	46.0
mesenchymal cell differentiation	0.105	0.1	0.197	195.0	-0.114	1.0	196.0
mol:Vitamin D3	-0.088	0.155	0.362	5.0	-0.334	53.0	58.0
IHH N/PTCH2	-0.095	0.131	0.201	5.0	-0.212	210.0	215.0
CDON	0.014	0.046	-9999.0	0.0	-0.328	7.0	7.0
IHH N/PTCH1	-0.097	0.176	0.237	30.0	-0.256	185.0	215.0
Megalin/LRPAP1	-0.037	0.115	0.238	1.0	-0.231	102.0	103.0
PTCH2	0.02	0.018	-9999.0	0.0	-0.328	1.0	1.0
SHH Np/Cholesterol	-0.028	0.051	-9999.0	0.0	-0.172	44.0	44.0
PTCH1	-0.106	0.164	0.234	3.0	-0.255	184.0	187.0
HHIP	-0.166	0.174	-9999.0	0.0	-0.328	209.0	209.0