Clinical Features MRNA_CNMF MRNA_CHIERARCHICAL CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nMutated (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q CDKN2A 26 (15%) 151 0.0013753 0.246 0.052972 1 0.0046914 0.816 0.60391 1 0.33991 1 0.20379 1 0.42322 1 0.20769 1 0.89881 1 0.53066 1 1 1 1 1 TP53 141 (80%) 36 0.082511 1 0.052173 1 0.00069583 0.126 0.00222 0.391 1 1 0.90185 1 0.020356 1 0.024258 1 0.56541 1 0.52501 1 0.011306 1 0.33059 1 NFE2L2 27 (15%) 150 0.00028734 0.0526 0.00081081 0.146 0.0013735 0.246 0.04706 1 0.25341 1 0.14367 1 9.8379e-07 0.000184 1.159e-05 0.00216 0.00052785 0.0961 3.5376e-05 0.00654 0.099606 1 0.0024921 0.436 PIK3CA 27 (15%) 150 0.64478 1 0.58603 1 0.45725 1 1 1 1 1 0.70924 1 0.28856 1 0.92387 1 0.37959 1 0.5803 1 0.81652 1 0.50235 1 PTEN 14 (8%) 163 0.37597 1 0.42658 1 0.32103 1 0.151 1 0.72126 1 0.4734 1 0.55594 1 0.15228 1 0.20061 1 0.65855 1 0.40622 1 0.83646 1 KEAP1 22 (12%) 155 0.0016277 0.288 0.00025256 0.0465 0.06441 1 0.071203 1 0.20419 1 0.096341 1 0.11984 1 0.0096105 1 0.87514 1 0.12598 1 0.41417 1 0.36665 1 CSMD3 81 (46%) 96 0.2381 1 0.88702 1 0.94539 1 0.30332 1 0.2651 1 0.76919 1 0.66735 1 0.5194 1 0.9459 1 0.80789 1 0.76633 1 0.93375 1 MLL2 35 (20%) 142 0.14447 1 0.83265 1 0.47079 1 0.39766 1 0.6964 1 0.2197 1 0.51087 1 0.5185 1 0.7258 1 0.75799 1 0.46606 1 0.41047 1 FBXW7 11 (6%) 166 0.45776 1 1 1 0.73584 1 NA NA 0.62139 1 0.78456 1 0.94507 1 0.70552 1 0.88828 1 1 1 NA NA NA NA RB1 12 (7%) 165 0.3431 1 0.19801 1 0.4887 1 0.83804 1 0.6571 1 0.43325 1 0.62259 1 0.29726 1 0.90547 1 0.71865 1 NA NA NA NA HS6ST1 5 (3%) 172 0.26873 1 0.29526 1 0.62301 1 NA NA NA NA NA NA 0.54237 1 0.067675 1 1 1 1 1 NA NA NA NA ZNF567 3 (2%) 174 NA NA NA NA 0.30756 1 NA NA 0.35868 1 0.42365 1 0.37792 1 0.074846 1 0.49786 1 0.25895 1 NA NA NA NA ELTD1 18 (10%) 159 0.029362 1 0.30656 1 0.19762 1 0.59721 1 0.34058 1 0.6478 1 0.25175 1 0.34091 1 0.19012 1 0.80945 1 0.76172 1 0.28907 1 ASCL4 6 (3%) 171 0.092379 1 0.53365 1 0.60255 1 0.78705 1 0.81655 1 0.83545 1 0.72217 1 0.18332 1 0.49553 1 0.73395 1 NA NA NA NA OR2G6 16 (9%) 161 0.36643 1 0.21058 1 0.12814 1 1 1 1 1 0.71709 1 0.30581 1 0.27766 1 0.50878 1 0.44795 1 1 1 0.36665 1 HLA-A 6 (3%) 171 0.039115 1 0.32963 1 0.37282 1 0.17614 1 1 1 0.51305 1 0.12342 1 0.12239 1 0.70548 1 0.62488 1 0.29864 1 0.11846 1 NOTCH1 14 (8%) 163 0.81203 1 0.92079 1 0.73373 1 0.046626 1 0.59052 1 0.82385 1 0.81159 1 0.56812 1 0.22422 1 0.16918 1 0.74151 1 0.51459 1