Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.029 0.111 0.452 22.0 -9999.0 0.0 22.0 KIRREL 0.001 0.072 -9999.0 0.0 -0.762 3.0 3.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.029 0.111 -9999.0 0.0 -0.453 22.0 22.0 PLCG1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.022 0.083 -9999.0 0.0 -0.441 3.0 3.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.012 0.047 -9999.0 0.0 -0.34 3.0 3.0 FYN -0.003 0.078 -9999.0 0.0 -0.417 3.0 3.0 mol:Ca2+ -0.022 0.082 -9999.0 0.0 -0.437 3.0 3.0 mol:DAG -0.022 0.082 -9999.0 0.0 -0.439 3.0 3.0 NPHS2 -0.002 0.047 -9999.0 0.0 -0.596 2.0 2.0 mol:IP3 -0.022 0.082 -9999.0 0.0 -0.439 3.0 3.0 regulation of endocytosis -0.018 0.068 -9999.0 0.0 -0.388 3.0 3.0 Nephrin/NEPH1/podocin/Cholesterol -0.023 0.085 -9999.0 0.0 -0.448 3.0 3.0 establishment of cell polarity -0.029 0.111 -9999.0 0.0 -0.452 22.0 22.0 Nephrin/NEPH1/podocin/NCK1-2 -0.02 0.074 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/beta Arrestin2 -0.018 0.068 -9999.0 0.0 -0.393 3.0 3.0 NPHS1 -0.026 0.138 -9999.0 0.0 -0.597 19.0 19.0 Nephrin/NEPH1/podocin -0.02 0.074 -9999.0 0.0 -0.419 3.0 3.0 TJP1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.022 0.083 -9999.0 0.0 -0.441 3.0 3.0 CD2AP 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.022 0.083 -9999.0 0.0 -0.441 3.0 3.0 GRB2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.02 0.131 -9999.0 0.0 -0.52 15.0 15.0 cytoskeleton organization -0.015 0.059 -9999.0 0.0 -0.416 3.0 3.0 Nephrin/NEPH1 -0.021 0.08 -9999.0 0.0 -0.324 22.0 22.0 Nephrin/NEPH1/ZO-1 -0.023 0.088 -9999.0 0.0 -0.474 3.0 3.0