Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 0.0 0.139 -9999.0 0.0 -0.354 16.0 16.0 MAP3K8 -0.012 0.145 -9999.0 0.0 -0.509 12.0 12.0 FOS 0.001 0.1 -9999.0 0.0 -0.413 4.0 4.0 PRKCA 0.025 0.048 -9999.0 0.0 -0.517 1.0 1.0 PTPN7 0.026 0.024 -9999.0 0.0 -9999.0 0.0 0.0 HRAS 0.029 0.045 -9999.0 0.0 -0.513 1.0 1.0 PRKCB -0.001 0.005 -9999.0 0.0 -0.016 15.0 15.0 NRAS 0.026 0.047 -9999.0 0.0 -0.508 1.0 1.0 RAS family/GTP 0.035 0.073 -9999.0 0.0 -0.292 6.0 6.0 MAPK3 0.018 0.055 -9999.0 0.0 -0.373 1.0 1.0 MAP2K1 -0.006 0.083 -9999.0 0.0 -0.377 4.0 4.0 ELK1 0.027 0.021 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.0 0.072 -9999.0 0.0 -0.413 4.0 4.0 mol:GTP -0.0 0.001 -9999.0 0.0 -0.005 14.0 14.0 MAPK1 0.005 0.106 -9999.0 0.0 -0.505 5.0 5.0 RAF1 0.005 0.05 -9999.0 0.0 -0.557 1.0 1.0 KRAS 0.017 0.086 -9999.0 0.0 -0.509 4.0 4.0