Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.329 0.376 0.728 18.0 -9999.0 0.0 18.0 KIRREL -0.044 0.163 -9999.0 0.0 -1.04 1.0 1.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.33 0.377 -9999.0 0.0 -0.73 18.0 18.0 PLCG1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.295 0.349 -9999.0 0.0 -0.832 8.0 8.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.171 0.248 -9999.0 0.0 -0.716 4.0 4.0 FYN -0.261 0.338 -9999.0 0.0 -0.785 8.0 8.0 mol:Ca2+ -0.29 0.343 -9999.0 0.0 -0.817 8.0 8.0 mol:DAG -0.293 0.346 -9999.0 0.0 -0.825 8.0 8.0 NPHS2 -0.111 0.259 -9999.0 0.0 -0.878 4.0 4.0 mol:IP3 -0.293 0.346 -9999.0 0.0 -0.825 8.0 8.0 regulation of endocytosis -0.255 0.307 -9999.0 0.0 -0.943 4.0 4.0 Nephrin/NEPH1/podocin/Cholesterol -0.299 0.353 -9999.0 0.0 -0.84 8.0 8.0 establishment of cell polarity -0.329 0.376 -9999.0 0.0 -0.728 18.0 18.0 Nephrin/NEPH1/podocin/NCK1-2 -0.272 0.326 -9999.0 0.0 -1.0 4.0 4.0 Nephrin/NEPH1/beta Arrestin2 -0.26 0.314 -9999.0 0.0 -0.969 4.0 4.0 NPHS1 -0.394 0.451 -9999.0 0.0 -0.889 18.0 18.0 Nephrin/NEPH1/podocin -0.276 0.331 -9999.0 0.0 -0.794 8.0 8.0 TJP1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.295 0.349 -9999.0 0.0 -0.832 8.0 8.0 CD2AP 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.295 0.349 -9999.0 0.0 -0.832 8.0 8.0 GRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.259 0.338 -9999.0 0.0 -0.777 8.0 8.0 cytoskeleton organization -0.235 0.341 -9999.0 0.0 -0.794 8.0 8.0 Nephrin/NEPH1 -0.254 0.295 -9999.0 0.0 -0.561 18.0 18.0 Nephrin/NEPH1/ZO-1 -0.275 0.319 -9999.0 0.0 -0.736 8.0 8.0