Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.052 0.143 0.451 20.0 -9999.0 0.0 20.0 KIRREL -0.04 0.171 -9999.0 0.0 -0.62 14.0 14.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.052 0.144 -9999.0 0.0 -0.452 20.0 20.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.039 0.106 -9999.0 0.0 -0.327 21.0 21.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.004 0.089 -9999.0 0.0 -0.277 14.0 14.0 FYN -0.021 0.104 -9999.0 0.0 -0.304 21.0 21.0 mol:Ca2+ -0.039 0.105 -9999.0 0.0 -0.332 14.0 14.0 mol:DAG -0.039 0.106 -9999.0 0.0 -0.334 14.0 14.0 NPHS2 -0.006 0.049 -9999.0 0.0 -0.598 1.0 1.0 mol:IP3 -0.039 0.106 -9999.0 0.0 -0.334 14.0 14.0 regulation of endocytosis -0.024 0.095 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/Cholesterol -0.04 0.108 -9999.0 0.0 -0.334 21.0 21.0 establishment of cell polarity -0.052 0.143 -9999.0 0.0 -0.451 20.0 20.0 Nephrin/NEPH1/podocin/NCK1-2 -0.035 0.095 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/beta Arrestin2 -0.013 0.1 -9999.0 0.0 -9999.0 0.0 0.0 NPHS1 -0.019 0.11 -9999.0 0.0 -0.598 6.0 6.0 Nephrin/NEPH1/podocin -0.034 0.1 -9999.0 0.0 -0.305 21.0 21.0 TJP1 0.005 0.065 -9999.0 0.0 -0.603 2.0 2.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.039 0.106 -9999.0 0.0 -0.335 14.0 14.0 CD2AP 0.012 0.001 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.039 0.106 -9999.0 0.0 -0.327 21.0 21.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.083 0.19 -9999.0 0.0 -0.393 44.0 44.0 cytoskeleton organization -0.004 0.105 -9999.0 0.0 -0.319 14.0 14.0 Nephrin/NEPH1 -0.037 0.103 -9999.0 0.0 -0.323 20.0 20.0 Nephrin/NEPH1/ZO-1 -0.045 0.119 -9999.0 0.0 -0.36 22.0 22.0