Clinical Features	Time to Death		AGE		PRIMARY.SITE.OF.DISEASE		GENDER		DISTANT.METASTASIS		LYMPH.NODE.METASTASIS		TUMOR.STAGECODE		NEOPLASM.DISEASESTAGE	
	nMutated (%)	nWild-Type	logrank test_P	logrank test_Q	t-test_P	t-test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Chi-square test_P	Chi-square test_Q	Chi-square test_P	Chi-square test_Q	t-test_P	t-test_Q	Chi-square test_P	Chi-square test_Q
C15ORF23	11 (7%)	150	0.5792	1	0.66973	1	0.81862	1	0.74748	1	0.96985	1	0.48789	1	NA	NA	0.67913	1
CDKN2A	27 (17%)	134	0.57088	1	0.99489	1	0.67053	1	1	1	0.82555	1	0.7464	1	NA	NA	0.36564	1
NRAS	49 (30%)	112	0.6999	1	0.39373	1	0.45399	1	1	1	0.61802	1	0.90985	1	NA	NA	0.59141	1
BRAF	82 (51%)	79	0.25616	1	0.096304	1	0.126	1	0.74631	1	0.56792	1	0.83492	1	NA	NA	0.63462	1
OXA1L	5 (3%)	156	0.69515	1	0.61261	1	0.65638	1	1	1	0.99232	1	0.00011977	0.0711	NA	NA	0.47997	1
TP53	26 (16%)	135	0.68661	1	0.069992	1	0.22083	1	0.82765	1	0.59027	1	0.096394	1	NA	NA	0.46438	1
STK19	10 (6%)	151	0.41464	1	0.33549	1	1	1	0.49964	1	0.97548	1	0.96513	1	NA	NA	0.7597	1
PTEN	13 (8%)	148	0.70296	1	0.23429	1	0.47259	1	0.55116	1	0.00028	0.165	0.83522	1	NA	NA	0.032529	1
DSG1	26 (16%)	135	0.090691	1	0.95604	1	0.6619	1	1	1	0.83824	1	0.25447	1	NA	NA	0.42216	1
PPP6C	15 (9%)	146	0.0041157	1	0.64684	1	0.64583	1	1	1	0.40178	1	0.048106	1	NA	NA	0.7553	1
RAC1	12 (7%)	149	0.089782	1	0.41537	1	0.57889	1	1	1	0.96985	1	0.89535	1	NA	NA	0.30331	1
AOAH	17 (11%)	144	0.69514	1	0.10031	1	0.010773	1	0.79123	1	0.36217	1	0.021889	1	NA	NA	0.73493	1
IDH1	8 (5%)	153	0.69727	1	0.0048264	1	1	1	0.4659	1	0.98055	1	0.98087	1	NA	NA	0.70329	1
OR51S1	17 (11%)	144	0.66768	1	0.42437	1	0.19695	1	1	1	0.93366	1	0.049636	1	NA	NA	0.20077	1
IL32	7 (4%)	154	0.033469	1	0.70243	1	0.53842	1	0.70763	1	0.98505	1	0.83346	1	NA	NA	0.0083185	1
PPIAL4G	11 (7%)	150	0.091662	1	0.037313	1	0.74061	1	0.33075	1	0.96985	1	0.032721	1	NA	NA	0.96989	1
UGT2B15	17 (11%)	144	0.64694	1	0.35961	1	0.77265	1	0.11187	1	0.11696	1	0.12559	1	NA	NA	0.14005	1
TTN	127 (79%)	34	0.18586	1	0.83739	1	1	1	0.16616	1	0.49625	1	0.35318	1	NA	NA	0.37613	1
THEMIS	16 (10%)	145	0.71661	1	0.40917	1	0.57578	1	1	1	0.92489	1	0.22348	1	NA	NA	0.61883	1
LRTM1	16 (10%)	145	0.88624	1	0.65426	1	0.71249	1	0.052718	1	0.038122	1	0.18554	1	NA	NA	0.61101	1
TCEB3C	23 (14%)	138	0.33368	1	0.4723	1	0.8645	1	0.15989	1	0.86246	1	0.53269	1	NA	NA	0.4576	1
ELF5	4 (2%)	157	0.56222	1	0.77507	1	0.60025	1	1	1	0.99721	1	0.27999	1	NA	NA	0.96974	1
GPR141	12 (7%)	149	0.61048	1	0.99343	1	0.30822	1	0.53789	1	0.95696	1	0.056978	1	NA	NA	0.28782	1
NMNAT3	5 (3%)	156	0.93282	1	0.54512	1	0.04775	1	1	1	0.99506	1	2.8875e-12	1.73e-09	NA	NA	0.12007	1
EIF2B1	8 (5%)	153	0.78157	1	0.772	1	0.083826	1	1	1	0.98505	1	0.93811	1	NA	NA	0.97466	1
CHGB	18 (11%)	143	0.12753	1	0.91813	1	0.51885	1	1	1	0.92489	1	0.15352	1	NA	NA	0.17266	1
COPG2	3 (2%)	158	0.45387	1	0.99708	1	0.72539	1	1	1	0.99721	1	0.99	1	NA	NA	0.044186	1
RAPGEF5	8 (5%)	153	0.99683	1	0.35962	1	0.10035	1	0.25977	1	0.98898	1	0.00027873	0.165	NA	NA	0.33083	1
MS4A2	8 (5%)	153	0.57971	1	0.52841	1	0.13612	1	0.25977	1	0.98505	1	0.0094035	1	NA	NA	0.86749	1
MPP7	19 (12%)	142	0.99227	1	0.023035	1	0.89145	1	0.44825	1	0.47102	1	0.097621	1	NA	NA	0.93531	1
C1QTNF9	10 (6%)	151	0.1764	1	0.63588	1	0.066424	1	0.32766	1	0.96985	1	0.90164	1	NA	NA	0.70214	1
DNAH7	60 (37%)	101	0.41356	1	0.072962	1	0.55222	1	0.12753	1	0.24736	1	0.27997	1	NA	NA	0.93894	1
FAM58A	3 (2%)	158	0.46672	1	0.40952	1	0.72539	1	0.29915	1	0.99721	1	0.41027	1	NA	NA	NA	NA
LCE1B	9 (6%)	152	0.061943	1	0.74967	1	0.081719	1	0.72558	1	0.98055	1	0.9334	1	NA	NA	0.67445	1
SCN5A	40 (25%)	121	0.63481	1	0.19898	1	0.45069	1	0.57489	1	0.26692	1	0.48086	1	NA	NA	0.43892	1
C6ORF223	3 (2%)	158	0.6614	1	0.60267	1	1	1	0.29915	1	0.99721	1	0.69724	1	NA	NA	0.34139	1
ANKRD20A4	4 (2%)	157	0.44898	1	0.53122	1	0.77753	1	0.29745	1	0.99506	1	1.6179e-05	0.00966	NA	NA	0.56372	1
LOC649330	20 (12%)	141	0.44399	1	0.030964	1	0.64287	1	0.32445	1	0.91563	1	0.23535	1	NA	NA	0.60406	1
KLRC3	4 (2%)	157	0.47093	1	0.68282	1	0.77753	1	0.62431	1	0.99506	1	0.37874	1	NA	NA	0.84799	1
UNC119B	3 (2%)	158	0.99895	1	0.37538	1	1	1	1	1	0.99721	1	0.99	1	NA	NA	0.55453	1
PENK	15 (9%)	146	0.72302	1	0.61054	1	0.076368	1	0.57524	1	0.94971	1	0.10587	1	NA	NA	0.37161	1
OR4E2	16 (10%)	145	0.13071	1	0.58712	1	0.39439	1	0.41591	1	0.40178	1	0.14388	1	NA	NA	0.55621	1
TSHB	4 (2%)	157	0.47107	1	0.95044	1	0.030541	1	1	1	0.99506	1	1.9387e-06	0.00116	NA	NA	0.31899	1
PRC1	9 (6%)	152	0.63525	1	0.44485	1	0.55147	1	0.48793	1	0.98055	1	0.71715	1	NA	NA	0.93064	1
SORT1	5 (3%)	156	0.34028	1	0.5997	1	0.059171	1	0.65302	1	0.99232	1	0.6963	1	NA	NA	0.14748	1
PCDP1	12 (7%)	149	0.3638	1	0.57959	1	0.6884	1	0.53789	1	0.96985	1	0.032721	1	NA	NA	0.14825	1
ZFP106	6 (4%)	155	0.52423	1	0.00061539	0.363	0.49122	1	0.086413	1	0.98898	1	0.80957	1	NA	NA	0.38172	1
TCHHL1	25 (16%)	136	0.7744	1	0.03101	1	0.19234	1	0.65793	1	0.1504	1	0.2069	1	NA	NA	0.10574	1
OR2W1	13 (8%)	148	0.5465	1	0.045886	1	0.84755	1	0.55116	1	0.95696	1	0.011625	1	NA	NA	0.93054	1
LRRC4C	25 (16%)	136	0.35892	1	0.055315	1	0.16115	1	0.65793	1	0.86246	1	0.42082	1	NA	NA	0.92762	1
SERPINB10	7 (4%)	154	0.43713	1	0.3269	1	0.23607	1	0.42422	1	0.98898	1	0.0024535	1	NA	NA	0.84454	1
C18ORF26	13 (8%)	148	0.60806	1	0.60964	1	0.038709	1	0.13512	1	0.96367	1	0.066808	1	NA	NA	0.87162	1
TBC1D3B	3 (2%)	158	0.0019848	1	0.40362	1	0.28548	1	1	1	NA	NA	NA	NA	NA	NA	NA	NA
CCNE2	10 (6%)	151	0.032427	1	0.87884	1	0.14115	1	1	1	0.96985	1	0.94609	1	NA	NA	0.47619	1
CAPZA3	13 (8%)	148	0.85919	1	0.097265	1	0.51452	1	1	1	0.31945	1	0.11397	1	NA	NA	0.78205	1
PROL1	15 (9%)	146	0.90699	1	0.22361	1	0.1685	1	0.25968	1	0.02768	1	0.12675	1	NA	NA	0.80748	1
CYP4X1	12 (7%)	149	0.55233	1	0.54335	1	0.8335	1	0.76011	1	0.96367	1	0.017279	1	NA	NA	0.92412	1
GCOM1	17 (11%)	144	0.36268	1	0.1649	1	0.25008	1	0.60224	1	0.43807	1	0.25543	1	NA	NA	0.13482	1
DGAT2L6	9 (6%)	152	0.36839	1	0.34937	1	0.031164	1	1	1	0.97548	1	0.011288	1	NA	NA	0.76212	1
EIF3D	3 (2%)	158	0.044383	1	0.48065	1	0.72539	1	0.29915	1	0.99721	1	0.97855	1	NA	NA	0.62777	1
B2M	4 (2%)	157	0.57747	1	0.40142	1	0.77753	1	0.29745	1	0.99721	1	0.99	1	NA	NA	0.65523	1
KCNB2	43 (27%)	118	0.71575	1	0.53289	1	0.45931	1	1	1	0.29273	1	0.14363	1	NA	NA	0.10582	1
KIAA2022	31 (19%)	130	0.51366	1	0.014374	1	0.27156	1	0.40856	1	0.8125	1	0.12191	1	NA	NA	0.34913	1
C9ORF119	5 (3%)	156	0.33311	1	0.33968	1	1	1	0.15912	1	0.99232	1	5.9054e-05	0.0351	NA	NA	0.81709	1
TUBAL3	8 (5%)	153	0.81106	1	0.63198	1	0.38832	1	0.71143	1	0.99232	1	2.5878e-05	0.0154	NA	NA	0.62082	1
C2	7 (4%)	154	0.48493	1	0.88266	1	0.74233	1	1	1	0.98898	1	0.00017194	0.102	NA	NA	0.34948	1
KIAA1486	19 (12%)	142	0.3318	1	0.027448	1	0.11601	1	0.073322	1	0.43807	1	0.23329	1	NA	NA	0.70079	1
APCS	9 (6%)	152	0.72232	1	0.29054	1	0.26254	1	1	1	0.089504	1	0.0051084	1	NA	NA	0.39279	1
SIRPB1	15 (9%)	146	0.84114	1	0.12781	1	0.24135	1	0.25968	1	0.94971	1	0.003185	1	NA	NA	0.52391	1
CYP7B1	14 (9%)	147	0.71631	1	0.73348	1	0.73171	1	0.25924	1	0.95696	1	0.11128	1	NA	NA	0.93495	1
SGCZ	19 (12%)	142	0.24318	1	0.89678	1	0.94513	1	1	1	0.94194	1	0.048226	1	NA	NA	0.18328	1
PDE1A	26 (16%)	135	0.66637	1	0.12962	1	0.018657	1	0.65731	1	0.83824	1	0.13649	1	NA	NA	0.70849	1
CYP4Z1	13 (8%)	148	0.19208	1	0.23946	1	1	1	1	1	0.27408	1	0.065899	1	NA	NA	0.68393	1
FAM113B	16 (10%)	145	0.32691	1	0.2779	1	0.0035288	1	0.052718	1	0.92489	1	0.16905	1	NA	NA	0.16208	1
SLC10A2	15 (9%)	146	0.4941	1	0.23833	1	0.15403	1	0.78414	1	0.94194	1	0.032034	1	NA	NA	0.08253	1
CX3CL1	3 (2%)	158	0.42697	1	0.93811	1	0.46944	1	1	1	NA	NA	NA	NA	NA	NA	NA	NA
C2ORF39	8 (5%)	153	0.58256	1	0.22011	1	1	1	0.71143	1	0.053031	1	0.0070851	1	NA	NA	0.57573	1
IGF2BP3	3 (2%)	158	0.85416	1	0.68747	1	0.46944	1	1	1	NA	NA	NA	NA	NA	NA	NA	NA
SLC9A11	28 (17%)	133	0.76636	1	0.70987	1	0.73221	1	0.084451	1	0.62033	1	0.42239	1	NA	NA	0.42034	1
HRNR	37 (23%)	124	0.34646	1	0.38987	1	0.91291	1	0.011562	1	0.67371	1	0.45056	1	NA	NA	0.60177	1
DDX3X	16 (10%)	145	0.5702	1	0.53819	1	0.54045	1	0.17164	1	0.0045641	1	0.9912	1	NA	NA	0.70414	1
TRHDE	33 (20%)	128	0.61638	1	0.13825	1	0.10327	1	0.23124	1	0.67371	1	0.3247	1	NA	NA	0.44933	1
SPTLC3	15 (9%)	146	0.21354	1	0.54645	1	0.34753	1	0.57524	1	0.93366	1	0.11937	1	NA	NA	0.17702	1
ACD	7 (4%)	154	0.91218	1	0.56283	1	0.028581	1	0.42422	1	0.98505	1	0.0044235	1	NA	NA	0.38402	1
ARL16	5 (3%)	156	0.2116	1	0.02708	1	0.059171	1	0.65302	1	0.99232	1	0.88489	1	NA	NA	0.15676	1
PHGDH	8 (5%)	153	0.7756	1	0.69544	1	0.58799	1	0.027315	1	0.98898	1	0.0021668	1	NA	NA	0.1427	1
DNER	15 (9%)	146	0.4786	1	0.10699	1	0.48454	1	0.053635	1	0.94194	1	0.21219	1	NA	NA	0.3851	1