Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.167 0.305 0.69 117.0 -9999.0 0.0 117.0 KIRREL -0.068 0.235 -9999.0 0.0 -0.848 40.0 40.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.167 0.305 -9999.0 0.0 -0.692 117.0 117.0 PLCG1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.13 0.242 -9999.0 0.0 -0.54 117.0 117.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.076 0.196 -9999.0 0.0 -0.408 117.0 117.0 FYN -0.11 0.236 -9999.0 0.0 -0.511 117.0 117.0 mol:Ca2+ -0.129 0.239 -9999.0 0.0 -0.534 117.0 117.0 mol:DAG -0.129 0.24 -9999.0 0.0 -0.537 117.0 117.0 NPHS2 -0.017 0.053 -9999.0 0.0 -0.898 1.0 1.0 mol:IP3 -0.129 0.24 -9999.0 0.0 -0.537 117.0 117.0 regulation of endocytosis -0.115 0.214 -9999.0 0.0 -0.477 117.0 117.0 Nephrin/NEPH1/podocin/Cholesterol -0.132 0.245 -9999.0 0.0 -0.548 117.0 117.0 establishment of cell polarity -0.167 0.305 -9999.0 0.0 -0.69 117.0 117.0 Nephrin/NEPH1/podocin/NCK1-2 -0.119 0.223 -9999.0 0.0 -0.494 117.0 117.0 Nephrin/NEPH1/beta Arrestin2 -0.114 0.219 -9999.0 0.0 -0.484 117.0 117.0 NPHS1 -0.155 0.323 -9999.0 0.0 -0.829 90.0 90.0 Nephrin/NEPH1/podocin -0.124 0.231 -9999.0 0.0 -0.514 117.0 117.0 TJP1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.13 0.242 -9999.0 0.0 -0.54 117.0 117.0 CD2AP 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.13 0.242 -9999.0 0.0 -0.54 117.0 117.0 GRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.112 0.243 -9999.0 0.0 -0.511 121.0 121.0 cytoskeleton organization -0.101 0.256 -9999.0 0.0 -0.536 117.0 117.0 Nephrin/NEPH1 -0.127 0.236 -9999.0 0.0 -0.528 117.0 117.0 Nephrin/NEPH1/ZO-1 -0.138 0.256 -9999.0 0.0 -0.573 117.0 117.0