		Clinical Features	CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nMutated (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
C15ORF23	14 (6%)	214	0.32019	1	0.28142	1	0.71284	1	0.84402	1	1	1	1	1	0.83069	1	0.661	1	0.33962	1	0.66305	1
POLDIP2	8 (4%)	220	0.60023	1	0.90042	1	0.66734	1	1	1	1	1	0.80708	1	0.72615	1	0.8815	1	0.9055	1	0.77049	1
NUDT11	8 (4%)	220	0.81336	1	0.66769	1	0.8084	1	1	1	0.74344	1	0.89747	1	0.88954	1	0.5246	1	0.80318	1	0.63402	1
CDKN2A	34 (15%)	194	0.10825	1	0.561	1	0.063153	1	0.2023	1	0.84257	1	0.22561	1	0.81237	1	0.73716	1	0.94438	1	0.6866	1
NRAS	67 (29%)	161	0.0687	1	0.086821	1	0.69564	1	0.015226	1	0.90008	1	0.68513	1	0.65546	1	0.75491	1	0.83759	1	0.54917	1
BRAF	117 (51%)	111	0.096406	1	0.040637	1	0.47546	1	0.25234	1	0.015138	1	0.0021599	1	0.080965	1	0.14682	1	0.32263	1	0.13658	1
OXA1L	7 (3%)	221	0.42623	1	0.79594	1	1	1	0.25571	1	0.49819	1	0.15083	1	0.53957	1	0.5246	1	0.80318	1	0.63402	1
TTN	177 (78%)	51	0.2795	1	0.01326	1	0.13355	1	0.56589	1	0.2662	1	0.21323	1	0.12181	1	0.38003	1	0.075551	1	0.3456	1
UGT2B15	21 (9%)	207	0.59262	1	0.3799	1	0.75497	1	0.87405	1	0.47968	1	0.91193	1	0.12516	1	0.49444	1	0.045141	1	0.71405	1
TP53	35 (15%)	193	0.15233	1	0.031791	1	0.23873	1	0.38383	1	0.19539	1	0.35789	1	0.29285	1	0.084193	1	0.69274	1	0.22727	1
STK19	11 (5%)	217	0.85713	1	0.084389	1	0.14086	1	0.44401	1	0.79955	1	1	1	0.61779	1	0.54796	1	0.23983	1	0.55634	1
PTEN	18 (8%)	210	0.52424	1	0.21651	1	0.097525	1	0.11439	1	0.95174	1	0.12568	1	0.95087	1	0.30097	1	0.86221	1	0.59547	1
DSG1	39 (17%)	189	0.23974	1	0.55015	1	0.11562	1	0.67999	1	0.75487	1	0.94653	1	0.45941	1	0.36786	1	0.71497	1	0.45972	1
PPP6C	18 (8%)	210	0.70809	1	0.44814	1	0.52645	1	0.20859	1	0.64213	1	0.2719	1	0.21856	1	0.13026	1	0.16854	1	0.28582	1
AOAH	21 (9%)	207	0.38412	1	0.23411	1	0.78111	1	1	1	0.42074	1	0.17132	1	0.33982	1	0.63214	1	0.8053	1	0.63535	1
RAC1	17 (7%)	211	0.096686	1	0.1856	1	0.74045	1	0.35292	1	0.5363	1	1	1	0.68774	1	0.42834	1	0.328	1	0.37842	1
OR51S1	27 (12%)	201	0.31465	1	0.90008	1	0.72368	1	0.10138	1	0.70863	1	0.59607	1	0.74934	1	0.8703	1	0.57239	1	0.42152	1
IDH1	12 (5%)	216	0.14568	1	0.26395	1	0.12531	1	0.096293	1	0.13113	1	0.50565	1	0.074829	1	0.077856	1	0.1688	1	0.11144	1
IL32	9 (4%)	219	0.20338	1	0.098939	1	1	1	0.44619	1	0.39346	1	1	1	0.75384	1	1	1	0.68695	1	1	1
PPIAL4G	12 (5%)	216	0.75404	1	0.75566	1	1	1	0.68924	1	0.21782	1	0.36195	1	0.93225	1	0.62321	1	0.21397	1	0.91041	1
THEMIS	27 (12%)	201	0.10688	1	0.0078399	1	0.58346	1	0.83114	1	0.68311	1	0.71472	1	0.014524	1	0.49873	1	0.36049	1	0.63344	1
LRTM1	23 (10%)	205	0.26406	1	0.72517	1	0.56427	1	0.77427	1	0.88912	1	0.68024	1	0.5387	1	0.50216	1	1	1	0.66083	1
TCEB3C	26 (11%)	202	0.74933	1	0.45035	1	0.56773	1	0.66537	1	0.45513	1	0.04451	1	0.50946	1	0.18543	1	1	1	0.2595	1
GPR141	14 (6%)	214	0.088497	1	0.41118	1	0.039729	1	0.075313	1	0.78248	1	0.72211	1	0.21648	1	1	1	0.15327	1	0.60754	1
CHGB	25 (11%)	203	0.71579	1	0.74126	1	0.27906	1	0.076218	1	0.31554	1	0.82095	1	0.82477	1	0.16188	1	0.39059	1	0.089271	1
ELF5	6 (3%)	222	0.28813	1	1	1	0.7069	1	0.36951	1	0.58347	1	1	1	0.26942	1	0.28684	1	0.43539	1	0.20592	1
NMNAT3	8 (4%)	220	0.17825	1	0.66769	1	0.8444	1	1	1	0.67262	1	0.89747	1	0.58238	1	0.1379	1	0.34168	1	0.12917	1
C6ORF223	6 (3%)	222	0.668	1	0.88016	1	0.57638	1	1	1	0.66946	1	0.22055	1	0.15277	1	0.58809	1	0.15313	1	0.59216	1
EIF2B1	9 (4%)	219	0.57289	1	0.25425	1	0.11717	1	1	1	0.52868	1	1	1	0.45262	1	0.53403	1	0.32113	1	0.62252	1
DNAH7	83 (36%)	145	0.85325	1	0.4643	1	0.20878	1	0.77376	1	0.93872	1	0.74926	1	0.63026	1	0.93904	1	0.52796	1	0.9017	1
COPG2	9 (4%)	219	0.23173	1	0.91037	1	0.64946	1	0.50639	1	0.69067	1	0.82051	1	0.68322	1	0.78491	1	0.57323	1	0.88791	1
RAPGEF5	12 (5%)	216	0.70146	1	0.64904	1	0.79308	1	0.82825	1	0.49024	1	0.79464	1	0.061365	1	0.068605	1	0.084609	1	0.25474	1
C1QTNF9	14 (6%)	214	1	1	0.64918	1	0.63079	1	0.77469	1	0.94043	1	0.098007	1	0.21648	1	0.20467	1	0.38985	1	0.056689	1
MS4A2	10 (4%)	218	0.20456	1	1	1	0.95623	1	1	1	0.84875	1	0.57942	1	0.65239	1	0.39808	1	0.60276	1	0.5826	1
SCN5A	57 (25%)	171	0.80643	1	0.82208	1	0.10144	1	0.54041	1	0.90743	1	0.82926	1	0.46166	1	0.75152	1	0.82219	1	0.60008	1
MPP7	25 (11%)	203	0.53115	1	0.63914	1	0.30973	1	0.40397	1	0.06683	1	0.24231	1	0.8912	1	0.77883	1	0.92823	1	0.74953	1
FAM58A	5 (2%)	223	0.18163	1	0.84986	1	0.90978	1	0.45227	1	0.15914	1	0.30158	1	0.84557	1	0.28987	1	0.22966	1	0.24008	1
TSHB	5 (2%)	223	0.859	1	0.4505	1	0.44955	1	0.7855	1	0.26545	1	0.42561	1	1	1	1	1	0.86266	1	1	1
LCE1B	12 (5%)	216	0.17099	1	0.64904	1	0.74972	1	0.50466	1	0.65621	1	0.92955	1	0.8648	1	0.90655	1	0.48675	1	0.91041	1
TCHHL1	31 (14%)	197	0.58882	1	0.038681	1	0.045887	1	0.30783	1	0.16759	1	0.11082	1	0.8509	1	0.55887	1	0.91102	1	0.33366	1
OR4E2	20 (9%)	208	0.12162	1	0.55731	1	0.84357	1	0.77295	1	0.32276	1	0.5888	1	0.7219	1	1	1	0.55384	1	0.23476	1
ANKRD20A4	5 (2%)	223	0.22632	1	0.4505	1	0.82776	1	1	1	0.15914	1	0.42561	1	0.72609	1	1	1	0.38878	1	1	1
LOC649330	24 (11%)	204	0.26485	1	0.37502	1	0.79793	1	0.65384	1	0.25894	1	0.31217	1	0.85396	1	0.46063	1	0.89078	1	0.77567	1
PENK	20 (9%)	208	0.38635	1	0.018412	1	0.38705	1	0.76552	1	0.020843	1	0.18481	1	0.18539	1	0.83704	1	0.14146	1	0.24844	1
KLRC3	10 (4%)	218	0.46502	1	0.60469	1	0.19803	1	0.30375	1	0.55615	1	0.12412	1	0.13112	1	1	1	0.10422	1	1	1
UNC119B	6 (3%)	222	0.2126	1	0.44496	1	0.53039	1	0.88136	1	0.28931	1	0.41294	1	1	1	0.7081	1	0.76986	1	0.47665	1
CAPZA3	17 (7%)	211	0.69692	1	0.21025	1	0.63404	1	0.41732	1	0.81225	1	0.54122	1	0.80534	1	0.75489	1	0.53396	1	0.46468	1
PRC1	13 (6%)	215	0.67406	1	0.41362	1	0.14086	1	0.50639	1	0.27981	1	0.70373	1	0.35103	1	0.83628	1	0.33942	1	0.42272	1
PCDP1	15 (7%)	213	0.6244	1	0.088121	1	0.53743	1	0.27359	1	0.4174	1	0.60497	1	0.47861	1	0.30182	1	0.55344	1	0.28777	1
PROL1	21 (9%)	207	0.24414	1	0.092169	1	0.25866	1	0.67484	1	0.8421	1	0.49928	1	0.26594	1	0.25919	1	0.22301	1	0.29337	1
SORT1	10 (4%)	218	0.55239	1	0.84619	1	0.024629	1	0.19668	1	0.20588	1	0.47794	1	0.91655	1	0.50463	1	0.55	1	0.51661	1
LRRC4C	33 (14%)	195	0.28634	1	0.37533	1	0.16366	1	0.57746	1	0.41667	1	0.2552	1	0.67301	1	0.45234	1	0.91661	1	0.39561	1
ZFP106	10 (4%)	218	0.77811	1	0.84619	1	0.67719	1	0.026914	1	0.47195	1	0.77109	1	0.54216	1	0.71905	1	1	1	0.72085	1
HRNR	48 (21%)	180	0.89622	1	0.686	1	0.71243	1	0.91617	1	0.97827	1	0.73628	1	0.2287	1	0.34533	1	0.17922	1	0.73086	1
OR2W1	17 (7%)	211	0.044981	1	0.77045	1	0.66193	1	0.42263	1	0.5363	1	1	1	0.49347	1	0.87423	1	0.40623	1	0.93372	1
KCNB2	52 (23%)	176	0.10744	1	0.0090617	1	0.24554	1	0.59572	1	0.37003	1	0.51217	1	0.63524	1	0.49994	1	0.51143	1	0.92236	1
C2	12 (5%)	216	0.066363	1	0.28773	1	0.73319	1	0.6182	1	0.071979	1	0.54733	1	0.14407	1	0.56574	1	0.1833	1	0.47327	1
GCOM1	21 (9%)	207	0.77183	1	0.67602	1	0.47529	1	0.50466	1	0.026889	1	0.37561	1	0.33982	1	0.67032	1	0.56814	1	0.94589	1
SERPINB10	13 (6%)	215	0.16322	1	0.87536	1	0.24989	1	0.42263	1	0.93827	1	0.80699	1	0.24003	1	0.83628	1	0.81949	1	0.77518	1
C18ORF26	14 (6%)	214	0.28039	1	0.88373	1	0.30339	1	0.14649	1	0.36881	1	0.10543	1	0.83069	1	0.22825	1	0.36441	1	0.23751	1
SGCZ	22 (10%)	206	0.27239	1	0.50769	1	0.35724	1	0.29356	1	0.78249	1	0.2084	1	0.87937	1	0.84792	1	0.39584	1	0.85112	1
CCNE2	12 (5%)	216	0.56417	1	0.64904	1	0.08924	1	0.30375	1	0.41902	1	0.033748	1	0.017134	1	0.23855	1	0.0060581	1	0.16013	1
CYP4X1	16 (7%)	212	0.19311	1	0.89512	1	0.97717	1	0.14649	1	0.72199	1	0.838	1	1	1	0.74415	1	0.89687	1	0.69712	1
POM121	15 (7%)	213	0.55589	1	0.70336	1	0.25757	1	0.19166	1	0.32672	1	0.69224	1	0.88529	1	0.42493	1	0.41514	1	0.73266	1
KIAA2022	44 (19%)	184	0.42714	1	0.47092	1	0.41819	1	0.57769	1	0.3911	1	0.27566	1	0.28582	1	0.34399	1	0.62461	1	0.37183	1
KIAA1486	25 (11%)	203	0.034052	1	0.041946	1	0.47007	1	0.79893	1	0.28148	1	0.59601	1	0.41136	1	0.95333	1	0.89413	1	0.86458	1
TBC1D3B	5 (2%)	223	0.18163	1	0.84986	1	0.19451	1	0.18033	1	0.85469	1	1	1	0.84557	1	0.63948	1	0.86266	1	0.65298	1
B2M	5 (2%)	223	1	1	0.84986	1	0.50825	1	1	1	0.31893	1	0.50962	1	0.039379	1	0.13086	1	0.61221	1	0.17814	1
DGAT2L6	11 (5%)	217	0.79421	1	0.42471	1	0.50004	1	0.62797	1	0.21784	1	0.3308	1	0.72815	1	0.6742	1	0.23983	1	0.74079	1
EIF3D	4 (2%)	224	0.82206	1	0.82971	1	0.2842	1	0.62071	1	1	1	0.34106	1	0.54436	1	1	1	0.3848	1	0.43283	1
SIRPB1	18 (8%)	210	0.054123	1	0.77992	1	0.16686	1	0.29013	1	0.19068	1	0.15877	1	0.62911	1	0.16591	1	0.63868	1	0.2024	1
CYP7B1	18 (8%)	210	0.084654	1	0.60834	1	0.4482	1	0.52722	1	0.33256	1	1	1	0.3745	1	0.58489	1	0.17803	1	0.9375	1
PDE1A	32 (14%)	196	0.32319	1	0.94137	1	0.78567	1	0.74004	1	0.09273	1	0.078547	1	0.45444	1	0.17734	1	0.1031	1	0.45188	1
C9ORF119	8 (4%)	220	0.12354	1	0.73791	1	0.63392	1	0.83213	1	0.60517	1	0.40916	1	0.41677	1	0.41718	1	0.1267	1	0.37093	1
TUBAL3	10 (4%)	218	0.38898	1	0.46693	1	0.48074	1	0.27571	1	0.71412	1	0.91233	1	1	1	0.64211	1	0.78077	1	0.80569	1
NUDT4	5 (2%)	223	0.38308	1	0.37236	1	0.39147	1	0.1473	1	1	1	0.36098	1	0.36507	1	0.50546	1	0.45404	1	0.51101	1
FAM113B	20 (9%)	208	0.799	1	0.55731	1	0.11525	1	0.39558	1	0.25327	1	0.19379	1	0.86874	1	0.74513	1	0.333	1	0.58714	1
CYP4Z1	19 (8%)	209	0.27489	1	0.058435	1	0.059965	1	0.59676	1	0.23861	1	0.17279	1	0.82575	1	0.68665	1	0.9535	1	0.41388	1
SLC9A11	36 (16%)	192	0.31308	1	0.08947	1	0.68771	1	0.048199	1	0.54832	1	0.60766	1	0.61533	1	0.47993	1	0.24374	1	0.86778	1
DISP1	30 (13%)	198	0.39584	1	0.65796	1	0.45954	1	0.082385	1	0.42251	1	1	1	0.48542	1	0.42489	1	0.063705	1	0.29721	1
C2ORF39	9 (4%)	219	0.91205	1	0.15771	1	0.7613	1	0.26202	1	0.040331	1	0.0097101	1	0.45262	1	0.88637	1	0.75763	1	0.88791	1
APCS	11 (5%)	217	1	1	0.063258	1	0.88489	1	0.73893	1	0.2625	1	0.4733	1	0.92216	1	0.29665	1	0.49293	1	0.50023	1
SLC10A2	20 (9%)	208	0.76419	1	0.11066	1	0.11032	1	0.3336	1	0.63908	1	0.31275	1	0.29065	1	0.10038	1	0.63452	1	0.15371	1
DNER	22 (10%)	206	0.22672	1	0.58053	1	0.96848	1	0.68385	1	0.81509	1	0.58658	1	0.38444	1	0.30472	1	0.15982	1	0.045388	1
FIGLA	3 (1%)	225	0.62332	1	0.6191	1	NA	NA	NA	NA	0.49323	1	0.31813	1	0.43942	1	0.68619	1	0.18987	1	0.6946	1
C7ORF58	29 (13%)	199	0.41158	1	0.05369	1	0.068131	1	0.063727	1	0.9382	1	0.84089	1	0.48807	1	0.19074	1	0.84941	1	0.2756	1
LPAR1	12 (5%)	216	0.87057	1	0.048529	1	0.78974	1	0.28427	1	0.41902	1	0.54733	1	0.79921	1	0.75152	1	0.93159	1	0.82624	1
ST6GAL2	33 (14%)	195	1	1	0.097902	1	0.44658	1	0.65384	1	0.50837	1	0.42555	1	0.176	1	0.47178	1	0.1186	1	0.58405	1
IGF2BP3	6 (3%)	222	0.33191	1	0.88016	1	NA	NA	NA	NA	0.51113	1	0.86667	1	0.12458	1	0.58809	1	0.33093	1	0.59216	1
DDX3X	18 (8%)	210	0.29741	1	1	1	0.9272	1	0.65615	1	0.74446	1	0.85688	1	0.73595	1	0.14121	1	0.7808	1	0.55407	1
POTEG	25 (11%)	203	0.18347	1	0.083571	1	0.31488	1	0.28237	1	0.69141	1	0.33899	1	0.6049	1	0.58241	1	0.23703	1	0.41666	1
FASLG	11 (5%)	217	0.28182	1	0.35617	1	0.43124	1	0.50466	1	0.49783	1	0.72038	1	0.92216	1	0.60994	1	0.074376	1	0.90226	1
SV2B	25 (11%)	203	0.13006	1	0.14743	1	0.943	1	0.85666	1	0.42501	1	0.88759	1	0.85741	1	0.70589	1	1	1	0.46011	1
ZFX	12 (5%)	216	0.93041	1	0.75566	1	0.48744	1	0.89487	1	0.36359	1	0.30703	1	0.017134	1	0.15217	1	0.047528	1	0.16013	1
PHGDH	9 (4%)	219	0.23173	1	0.91037	1	0.52852	1	0.6182	1	0.75655	1	0.67509	1	0.61966	1	0.40371	1	1	1	0.41907	1
ARL16	7 (3%)	221	0.80252	1	0.30531	1	0.8084	1	0.17863	1	0.34137	1	1	1	0.88954	1	0.86965	1	0.23645	1	1	1
SPTLC3	17 (7%)	211	0.62655	1	0.90298	1	0.9079	1	0.41299	1	0.0089017	1	0.45662	1	0.39382	1	0.304	1	0.48087	1	0.40236	1
CX3CL1	4 (2%)	224	0.17733	1	0.13073	1	NA	NA	NA	NA	1	1	0.25828	1	0.079477	1	0.42188	1	0.47345	1	0.43283	1
ACD	9 (4%)	219	0.32237	1	0.75727	1	0.95623	1	0.41606	1	0.39346	1	0.21631	1	0.065798	1	0.11073	1	0.43388	1	0.19921	1
TRHDE	41 (18%)	187	0.30254	1	0.40709	1	0.35335	1	0.68822	1	0.51346	1	0.83124	1	0.68067	1	0.76974	1	0.37917	1	0.32012	1
ADAMTS2	24 (11%)	204	0.032372	1	0.79444	1	0.20436	1	0.9527	1	0.85787	1	0.31217	1	0.22317	1	0.17725	1	0.47956	1	0.42388	1
NF1	32 (14%)	196	0.14824	1	0.49551	1	0.37365	1	0.28141	1	0.54867	1	0.092476	1	0.8295	1	0.85199	1	0.26807	1	0.78898	1
OR4K1	26 (11%)	202	0.5622	1	0.96509	1	0.18989	1	0.91111	1	0.70189	1	0.52107	1	0.56951	1	0.39892	1	0.24976	1	0.30438	1
PCSK1	19 (8%)	209	0.83157	1	0.56267	1	0.38722	1	0.69816	1	1	1	0.95113	1	1	1	0.49392	1	1	1	0.22039	1
KRT78	16 (7%)	212	0.10863	1	0.38719	1	0.77177	1	0.45141	1	0.31467	1	0.49134	1	0.7102	1	0.41391	1	0.89687	1	0.35824	1
ZNF595	10 (4%)	218	1	1	0.60469	1	0.76593	1	0.37814	1	0.22742	1	0.57942	1	0.8388	1	0.64211	1	0.9191	1	0.5826	1
AMHR2	14 (6%)	214	0.94033	1	0.83056	1	0.85272	1	0.72765	1	0.73642	1	0.54794	1	0.72672	1	0.77747	1	0.78196	1	0.7821	1
RBM46	15 (7%)	213	0.94312	1	0.13587	1	0.2668	1	0.051397	1	0.94337	1	0.82923	1	0.23765	1	0.27657	1	0.70805	1	0.20588	1
IL1F7	10 (4%)	218	0.91968	1	0.46693	1	0.085125	1	0.69836	1	0.71412	1	0.70615	1	1	1	1	1	0.55	1	1	1
PREX2	55 (24%)	173	0.52686	1	0.068989	1	0.69971	1	0.62271	1	0.19346	1	0.30712	1	0.68774	1	0.037443	1	0.98006	1	0.066813	1
TRIOBP	35 (15%)	193	0.75482	1	1	1	0.84318	1	0.33999	1	0.27358	1	0.71959	1	0.44085	1	0.59364	1	0.53867	1	0.71799	1
ENAM	31 (14%)	197	0.91142	1	0.42962	1	0.20317	1	0.19218	1	0.42022	1	0.23743	1	0.49197	1	0.51524	1	0.73378	1	0.84979	1
RBM22	7 (3%)	221	0.42623	1	0.17235	1	0.68057	1	0.46899	1	0.34137	1	0.52698	1	0.88954	1	0.61964	1	0.80318	1	0.36613	1
GK2	29 (13%)	199	0.50116	1	0.451	1	0.58881	1	0.067836	1	0.90882	1	0.87031	1	0.28057	1	0.87791	1	0.61142	1	0.31238	1
CACNA1H	21 (9%)	207	0.74056	1	0.17761	1	0.14547	1	0.69943	1	0.5717	1	0.87126	1	0.25337	1	0.75362	1	0.8787	1	1	1
