Clinical Features	Time to Death		AGE		NEOPLASM.DISEASESTAGE		PATHOLOGY.T.STAGE		PATHOLOGY.N.STAGE		PATHOLOGY.M.STAGE		GENDER		KARNOFSKY.PERFORMANCE.SCORE		NUMBERPACKYEARSSMOKED		NUMBER.OF.LYMPH.NODES	
	nCNV (%)	nWild-Type	logrank test_P	logrank test_Q	t-test_P	t-test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	t-test_P	t-test_Q	t-test_P	t-test_Q	t-test_P	t-test_Q
1P GAIN MUTATION ANALYSIS	39 (26%)	113	0.014214	1	0.60196	1	0.73923	1	0.86323	1	0.13434	1	0.25946	1	0.38792	1	0.38929	1	0.020792	1	0.57247	1
1Q GAIN MUTATION ANALYSIS	50 (33%)	102	0.0005935	0.469	0.50633	1	0.037151	1	0.29246	1	0.012735	1	0.03713	1	0.8401	1	0.76757	1	0.021228	1	0.17255	1
2P GAIN MUTATION ANALYSIS	44 (29%)	108	0.28409	1	0.065972	1	0.035304	1	0.96632	1	0.0053946	1	0.6656	1	0.0027801	1	0.62843	1	0.56568	1	0.089415	1
2Q GAIN MUTATION ANALYSIS	21 (14%)	131	0.13166	1	0.93584	1	0.45131	1	0.0871	1	0.68268	1	0.10412	1	1	1	0.10292	1	0.66329	1	0.45759	1
3P GAIN MUTATION ANALYSIS	53 (35%)	99	0.84845	1	0.087446	1	0.20816	1	0.31894	1	0.46715	1	0.86093	1	1	1	0.10197	1	0.7007	1	0.35267	1
3Q GAIN MUTATION ANALYSIS	72 (47%)	80	0.12044	1	0.15874	1	0.10151	1	0.69234	1	0.04806	1	0.75369	1	0.56698	1	0.49706	1	0.86106	1	0.16181	1
4P GAIN MUTATION ANALYSIS	14 (9%)	138	0.069103	1	0.90252	1	0.74207	1	0.19962	1	0.10941	1	0.15956	1	1	1	0.72853	1	0.68787	1	0.78008	1
4Q GAIN MUTATION ANALYSIS	8 (5%)	144	0.11962	1	0.57123	1	0.58307	1	0.75975	1	0.52656	1	0.35793	1	1	1	NA	NA	0.78136	1	0.0003294	0.261
5P GAIN MUTATION ANALYSIS	56 (37%)	96	0.64659	1	0.32842	1	0.71564	1	0.41021	1	0.05402	1	0.33574	1	0.11446	1	0.89901	1	0.98372	1	0.1675	1
5Q GAIN MUTATION ANALYSIS	22 (14%)	130	0.89487	1	0.75121	1	0.050569	1	0.29108	1	0.042802	1	1	1	0.28785	1	0.78983	1	0.93711	1	3.3511e-05	0.0265
6P GAIN MUTATION ANALYSIS	23 (15%)	129	0.35643	1	0.87405	1	0.91582	1	0.57024	1	0.20129	1	0.44505	1	0.28713	1	0.50227	1	0.069234	1	1	1
6Q GAIN MUTATION ANALYSIS	15 (10%)	137	0.8634	1	0.48012	1	1	1	0.69611	1	0.017752	1	0.3637	1	0.1218	1	0.4101	1	0.11876	1	0.82943	1
7P GAIN MUTATION ANALYSIS	60 (39%)	92	0.26724	1	0.041617	1	0.11784	1	0.60851	1	0.2666	1	0.95148	1	0.84576	1	0.63397	1	0.64445	1	0.44172	1
7Q GAIN MUTATION ANALYSIS	54 (36%)	98	0.59421	1	0.067635	1	0.37541	1	0.78231	1	0.0088134	1	0.4343	1	0.23356	1	0.4633	1	0.17008	1	0.27685	1
8P GAIN MUTATION ANALYSIS	32 (21%)	120	0.59239	1	0.54908	1	0.39037	1	0.15072	1	0.86309	1	0.60501	1	0.64011	1	0.65581	1	0.50555	1	0.0095387	1
8Q GAIN MUTATION ANALYSIS	70 (46%)	82	0.32629	1	0.60872	1	0.33399	1	0.60072	1	0.88801	1	0.95424	1	0.18578	1	0.29248	1	0.45353	1	0.083918	1
9P GAIN MUTATION ANALYSIS	27 (18%)	125	0.0065258	1	0.23313	1	0.51047	1	0.61949	1	0.55509	1	0.335	1	0.6207	1	0.37888	1	0.2045	1	0.77475	1
9Q GAIN MUTATION ANALYSIS	21 (14%)	131	0.11306	1	0.17072	1	0.13565	1	1	1	0.1927	1	0.019624	1	0.58504	1	0.95099	1	0.23558	1	0.60097	1
10P GAIN MUTATION ANALYSIS	39 (26%)	113	0.29971	1	0.85408	1	0.53228	1	0.66998	1	0.30883	1	0.25946	1	0.66686	1	0.58009	1	0.99453	1	0.44986	1
10Q GAIN MUTATION ANALYSIS	12 (8%)	140	0.16745	1	0.32061	1	0.22826	1	0.25	1	0.14914	1	0.84763	1	0.73234	1	NA	NA	0.31078	1	0.29854	1
11P GAIN MUTATION ANALYSIS	12 (8%)	140	0.01524	1	0.47195	1	0.94011	1	0.91131	1	0.46195	1	0.69563	1	0.29561	1	0.70862	1	0.75247	1	0.52598	1
11Q GAIN MUTATION ANALYSIS	19 (12%)	133	0.97835	1	0.55641	1	0.93021	1	0.9418	1	0.16769	1	0.57635	1	0.56573	1	0.65363	1	0.64609	1	0.49179	1
12P GAIN MUTATION ANALYSIS	45 (30%)	107	0.98904	1	0.048657	1	0.47355	1	0.18959	1	0.82154	1	0.37983	1	1	1	0.8227	1	0.57102	1	0.64775	1
12Q GAIN MUTATION ANALYSIS	37 (24%)	115	0.81408	1	0.84354	1	0.49632	1	0.50443	1	0.5288	1	0.20133	1	0.51011	1	0.87433	1	0.092603	1	0.6664	1
13Q GAIN MUTATION ANALYSIS	37 (24%)	115	0.88349	1	0.49411	1	0.31143	1	1	1	0.18524	1	0.1951	1	0.37479	1	0.29154	1	0.25167	1	0.78717	1
14Q GAIN MUTATION ANALYSIS	26 (17%)	126	0.53541	1	0.67174	1	0.75089	1	0.6223	1	0.29135	1	0.1238	1	0.62333	1	0.58963	1	0.57679	1	0.074245	1
15Q GAIN MUTATION ANALYSIS	15 (10%)	137	0.85196	1	0.45183	1	0.79648	1	0.86024	1	0.093649	1	0.074305	1	0.75451	1	0.3493	1	0.020027	1	0.89763	1
16P GAIN MUTATION ANALYSIS	27 (18%)	125	0.032841	1	0.39869	1	0.79568	1	0.047701	1	0.33059	1	0.37861	1	0.80423	1	0.69935	1	0.43657	1	0.67254	1
16Q GAIN MUTATION ANALYSIS	29 (19%)	123	0.2622	1	0.93785	1	0.36172	1	0.063703	1	0.33894	1	0.31579	1	0.054166	1	0.86662	1	0.71008	1	0.43173	1
17P GAIN MUTATION ANALYSIS	21 (14%)	131	0.00068119	0.537	0.10789	1	0.097487	1	0.5137	1	0.36789	1	0.37314	1	0.58504	1	0.56888	1	0.75563	1	0.026596	1
17Q GAIN MUTATION ANALYSIS	52 (34%)	100	0.042699	1	0.24538	1	0.15999	1	0.55846	1	0.028904	1	0.69327	1	0.54854	1	0.027683	1	0.6658	1	0.73989	1
18P GAIN MUTATION ANALYSIS	40 (26%)	112	0.83135	1	0.63449	1	1	1	0.45733	1	0.3872	1	0.88061	1	1	1	0.033447	1	0.14141	1	0.74772	1
18Q GAIN MUTATION ANALYSIS	18 (12%)	134	0.25071	1	0.85289	1	0.89451	1	0.16819	1	0.74122	1	0.70566	1	0.56613	1	0.0072152	1	0.30274	1	0.97707	1
19P GAIN MUTATION ANALYSIS	30 (20%)	122	0.29052	1	0.54504	1	0.95482	1	0.37628	1	0.06301	1	0.68849	1	0.81081	1	0.70663	1	0.71263	1	0.47921	1
19Q GAIN MUTATION ANALYSIS	52 (34%)	100	0.47635	1	0.95977	1	0.11168	1	0.10114	1	0.1113	1	0.55229	1	0.84153	1	0.082885	1	0.16949	1	0.22483	1
20P GAIN MUTATION ANALYSIS	81 (53%)	71	0.15926	1	0.40872	1	0.70705	1	0.79617	1	0.59386	1	0.48976	1	0.84902	1	0.57876	1	0.052784	1	0.21084	1
20Q GAIN MUTATION ANALYSIS	92 (61%)	60	0.98809	1	0.77975	1	0.91797	1	0.27125	1	0.60843	1	0.52823	1	0.33024	1	0.49089	1	0.038897	1	0.76164	1
21Q GAIN MUTATION ANALYSIS	51 (34%)	101	0.25274	1	0.037208	1	0.38699	1	0.46695	1	0.25154	1	0.90501	1	0.42812	1	0.94737	1	0.13092	1	0.9525	1
22Q GAIN MUTATION ANALYSIS	28 (18%)	124	0.37924	1	0.84949	1	0.66116	1	0.80205	1	0.90195	1	0.73864	1	1	1	0.31571	1	0.83053	1	0.020353	1
XQ GAIN MUTATION ANALYSIS	20 (13%)	132	0.59823	1	0.87014	1	0.3169	1	0.26011	1	0.83321	1	0.74012	1	1	1	0.36809	1	0.63263	1	0.011832	1
1P LOSS MUTATION ANALYSIS	11 (7%)	141	0.79583	1	0.3962	1	0.50358	1	0.4076	1	0.34707	1	0.049135	1	1	1	NA	NA	0.058289	1	0.90904	1
1Q LOSS MUTATION ANALYSIS	12 (8%)	140	0.96101	1	0.35972	1	0.93922	1	0.4076	1	0.77814	1	1	1	1	1	0.19004	1	0.011804	1	0.86179	1
2P LOSS MUTATION ANALYSIS	15 (10%)	137	0.54825	1	0.70854	1	0.79648	1	0.45887	1	0.22483	1	0.56717	1	0.1218	1	0.53473	1	0.31372	1	0.44131	1
2Q LOSS MUTATION ANALYSIS	33 (22%)	119	0.064437	1	0.42084	1	0.37963	1	0.75326	1	0.046729	1	0.93289	1	1	1	0.41031	1	0.22555	1	0.61054	1
3P LOSS MUTATION ANALYSIS	23 (15%)	129	0.44422	1	0.52595	1	0.9405	1	0.90173	1	0.46498	1	0.24466	1	0.06724	1	0.98031	1	0.58802	1	0.48227	1
3Q LOSS MUTATION ANALYSIS	8 (5%)	144	0.052563	1	0.69124	1	0.58307	1	0.87003	1	0.57717	1	0.21876	1	1	1	0.03371	1	0.49337	1	2.6902e-06	0.00213
4P LOSS MUTATION ANALYSIS	51 (34%)	101	0.054794	1	0.05413	1	0.24261	1	0.94056	1	0.22905	1	0.6515	1	0.8401	1	0.88981	1	0.18674	1	0.44235	1
4Q LOSS MUTATION ANALYSIS	47 (31%)	105	0.48363	1	0.01213	1	0.53679	1	0.63521	1	0.80151	1	0.85232	1	1	1	0.63583	1	0.26711	1	0.45607	1
5P LOSS MUTATION ANALYSIS	29 (19%)	123	0.058939	1	0.043156	1	0.71492	1	0.63381	1	0.4238	1	0.21552	1	0.62921	1	0.036748	1	0.45132	1	0.52819	1
5Q LOSS MUTATION ANALYSIS	57 (38%)	95	0.92762	1	0.050276	1	0.040444	1	0.21183	1	0.048148	1	0.012556	1	0.4309	1	0.069153	1	0.85311	1	0.16707	1
6P LOSS MUTATION ANALYSIS	38 (25%)	114	0.76025	1	0.28691	1	0.012329	1	0.065895	1	0.020611	1	0.68975	1	0.66402	1	0.72461	1	0.91469	1	0.13247	1
6Q LOSS MUTATION ANALYSIS	53 (35%)	99	0.96343	1	0.28379	1	0.038649	1	0.4312	1	0.01785	1	0.95173	1	1	1	0.43631	1	0.5107	1	0.015847	1
7P LOSS MUTATION ANALYSIS	6 (4%)	146	0.10065	1	0.93671	1	0.56905	1	1	1	0.1679	1	0.7357	1	0.33647	1	NA	NA	0.8691	1	0.42528	1
7Q LOSS MUTATION ANALYSIS	9 (6%)	143	0.89328	1	0.89229	1	0.75956	1	0.728	1	0.82316	1	0.20361	1	0.116	1	NA	NA	0.0053526	1	0.89746	1
8P LOSS MUTATION ANALYSIS	62 (41%)	90	0.64141	1	0.29843	1	0.10918	1	0.33343	1	0.084606	1	0.0011513	0.906	0.33623	1	0.11332	1	0.17065	1	0.58238	1
8Q LOSS MUTATION ANALYSIS	13 (9%)	139	0.78742	1	0.053615	1	0.30838	1	0.068269	1	0.15852	1	0.035252	1	0.50793	1	NA	NA	0.97263	1	0.35569	1
9P LOSS MUTATION ANALYSIS	59 (39%)	93	0.38338	1	0.01764	1	0.71161	1	1	1	0.4857	1	0.90414	1	0.55759	1	0.79227	1	0.56388	1	0.47379	1
9Q LOSS MUTATION ANALYSIS	56 (37%)	96	0.49804	1	0.13079	1	0.83569	1	0.68017	1	0.90198	1	0.73771	1	0.23778	1	0.86466	1	0.097785	1	0.90297	1
10P LOSS MUTATION ANALYSIS	30 (20%)	122	0.24325	1	0.76901	1	1	1	0.61949	1	0.36699	1	0.2564	1	1	1	0.024064	1	0.23061	1	0.44444	1
10Q LOSS MUTATION ANALYSIS	50 (33%)	102	0.34948	1	0.0045104	1	0.88463	1	0.53685	1	0.76915	1	0.5437	1	1	1	0.061498	1	0.88047	1	0.74483	1
11P LOSS MUTATION ANALYSIS	59 (39%)	93	0.3344	1	0.039512	1	0.03914	1	0.61161	1	0.1645	1	0.12473	1	0.8451	1	0.24372	1	0.19553	1	0.1683	1
11Q LOSS MUTATION ANALYSIS	43 (28%)	109	0.14768	1	0.96667	1	0.2087	1	0.24267	1	0.10501	1	0.62561	1	0.83254	1	0.68506	1	0.018815	1	0.20865	1
12P LOSS MUTATION ANALYSIS	15 (10%)	137	0.90577	1	0.16295	1	1	1	0.16019	1	0.83403	1	0.56717	1	0.1218	1	0.66706	1	0.13604	1	0.48918	1
12Q LOSS MUTATION ANALYSIS	18 (12%)	134	0.68818	1	0.83683	1	0.24983	1	0.31886	1	0.0042473	1	0.37182	1	0.24453	1	0.57885	1	0.14137	1	0.24331	1
13Q LOSS MUTATION ANALYSIS	34 (22%)	118	0.080548	1	0.17273	1	0.946	1	0.58694	1	0.93835	1	0.67409	1	0.070367	1	0.0022961	1	0.51988	1	0.95215	1
14Q LOSS MUTATION ANALYSIS	41 (27%)	111	0.24467	1	0.074223	1	0.86175	1	0.93035	1	0.45667	1	0.8842	1	0.13475	1	0.86932	1	0.1941	1	0.55113	1
15Q LOSS MUTATION ANALYSIS	48 (32%)	104	0.27029	1	0.087949	1	0.92102	1	1	1	0.59068	1	0.11476	1	0.41346	1	0.34683	1	0.97687	1	0.24035	1
16P LOSS MUTATION ANALYSIS	38 (25%)	114	0.43886	1	0.13975	1	0.18072	1	0.095538	1	0.44335	1	0.54292	1	1	1	0.7616	1	0.74641	1	0.13931	1
16Q LOSS MUTATION ANALYSIS	36 (24%)	116	0.80099	1	0.30348	1	0.60657	1	0.62097	1	0.21073	1	0.31784	1	0.36934	1	0.91445	1	0.67343	1	0.55677	1
17P LOSS MUTATION ANALYSIS	64 (42%)	88	0.93026	1	0.14952	1	0.15433	1	0.97116	1	0.92458	1	0.86269	1	0.44466	1	0.46165	1	0.28902	1	0.47923	1
17Q LOSS MUTATION ANALYSIS	19 (12%)	133	0.75831	1	0.64225	1	0.67795	1	0.23631	1	0.24978	1	0.05283	1	1	1	0.93357	1	0.48958	1	0.37062	1
18P LOSS MUTATION ANALYSIS	39 (26%)	113	0.26056	1	0.52549	1	0.14351	1	0.16056	1	0.24589	1	0.2774	1	0.51303	1	0.18876	1	0.92906	1	0.83401	1
18Q LOSS MUTATION ANALYSIS	60 (39%)	92	0.78017	1	0.2108	1	0.67525	1	0.29005	1	0.89217	1	0.78427	1	0.17246	1	0.81543	1	0.93091	1	0.62641	1
19P LOSS MUTATION ANALYSIS	35 (23%)	117	0.062282	1	0.06984	1	0.016031	1	0.13648	1	0.00067883	0.536	0.024284	1	1	1	0.024577	1	0.23257	1	0.70065	1
19Q LOSS MUTATION ANALYSIS	19 (12%)	133	0.029126	1	0.24386	1	0.70804	1	0.073743	1	0.080078	1	0.18373	1	0.56573	1	0.19004	1	0.92598	1	0.54485	1
20P LOSS MUTATION ANALYSIS	12 (8%)	140	0.52249	1	0.69471	1	0.67969	1	1	1	0.41665	1	0.5471	1	0.73234	1	0.03371	1	0.029913	1	0.86867	1
20Q LOSS MUTATION ANALYSIS	5 (3%)	147	0.92761	1	0.99714	1	0.11115	1	0.37059	1	0.042499	1	0.70431	1	0.33906	1	NA	NA	0.0033019	1	0.46845	1
21Q LOSS MUTATION ANALYSIS	24 (16%)	128	0.15378	1	0.11109	1	0.51563	1	0.221	1	0.015064	1	0.92483	1	0.19798	1	0.066434	1	0.59151	1	0.86398	1
22Q LOSS MUTATION ANALYSIS	49 (32%)	103	0.31978	1	0.060135	1	0.58291	1	0.96805	1	0.39982	1	0.045751	1	0.84156	1	0.21266	1	0.13924	1	0.73006	1
XQ LOSS MUTATION ANALYSIS	32 (21%)	120	0.58626	1	0.70595	1	0.042103	1	0.049818	1	0.33233	1	0.33406	1	0.34867	1	0.92975	1	0.69421	1	0.66082	1