Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.054 0.146 0.527 13.0 -9999.0 0.0 13.0 KIRREL -0.036 0.168 -9999.0 0.0 -0.657 12.0 12.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.054 0.147 -9999.0 0.0 -0.528 13.0 13.0 PLCG1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.06 0.143 -9999.0 0.0 -0.447 18.0 18.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.018 0.117 -9999.0 0.0 -0.35 17.0 17.0 FYN -0.042 0.142 -9999.0 0.0 -0.418 19.0 19.0 mol:Ca2+ -0.059 0.142 -9999.0 0.0 -0.443 18.0 18.0 mol:DAG -0.06 0.142 -9999.0 0.0 -0.445 18.0 18.0 NPHS2 -0.047 0.167 -9999.0 0.0 -0.605 14.0 14.0 mol:IP3 -0.06 0.142 -9999.0 0.0 -0.445 18.0 18.0 regulation of endocytosis -0.039 0.132 -9999.0 0.0 -0.388 19.0 19.0 Nephrin/NEPH1/podocin/Cholesterol -0.061 0.146 -9999.0 0.0 -0.455 18.0 18.0 establishment of cell polarity -0.054 0.146 -9999.0 0.0 -0.527 13.0 13.0 Nephrin/NEPH1/podocin/NCK1-2 -0.054 0.13 -9999.0 0.0 -0.406 18.0 18.0 Nephrin/NEPH1/beta Arrestin2 -0.032 0.136 -9999.0 0.0 -0.393 19.0 19.0 NPHS1 -0.029 0.109 -9999.0 0.0 -0.451 11.0 11.0 Nephrin/NEPH1/podocin -0.048 0.141 -9999.0 0.0 -0.421 19.0 19.0 TJP1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.06 0.143 -9999.0 0.0 -0.447 18.0 18.0 CD2AP 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.06 0.143 -9999.0 0.0 -0.447 18.0 18.0 GRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.041 0.141 -9999.0 0.0 -0.411 18.0 18.0 cytoskeleton organization -0.021 0.141 -9999.0 0.0 -0.421 17.0 17.0 Nephrin/NEPH1 -0.039 0.107 -9999.0 0.0 -0.401 12.0 12.0 Nephrin/NEPH1/ZO-1 -0.042 0.117 -9999.0 0.0 -0.452 11.0 11.0