Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity -0.015 0.094 0.363 9.0 -0.19 2.0 11.0 KIRREL 0.0 0.116 -9999.0 0.0 -0.492 9.0 9.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs 0.015 0.095 0.191 2.0 -0.364 9.0 11.0 PLCG1 0.025 0.007 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.024 0.008 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.027 0.003 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.031 0.099 -9999.0 0.0 -0.271 15.0 15.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.0 0.074 -9999.0 0.0 -0.251 13.0 13.0 FYN -0.003 0.106 0.285 8.0 -0.253 16.0 24.0 mol:Ca2+ 0.026 0.098 -9999.0 0.0 -0.269 15.0 15.0 mol:DAG 0.027 0.098 -9999.0 0.0 -0.27 15.0 15.0 NPHS2 -0.015 0.101 -9999.0 0.0 -0.486 7.0 7.0 mol:IP3 0.027 0.098 -9999.0 0.0 -0.27 15.0 15.0 regulation of endocytosis 0.021 0.085 -9999.0 0.0 -0.234 15.0 15.0 Nephrin/NEPH1/podocin/Cholesterol 0.018 0.093 -9999.0 0.0 -0.267 15.0 15.0 establishment of cell polarity 0.015 0.094 0.19 2.0 -0.363 9.0 11.0 Nephrin/NEPH1/podocin/NCK1-2 0.04 0.095 -9999.0 0.0 -0.248 14.0 14.0 Nephrin/NEPH1/beta Arrestin2 0.022 0.086 -9999.0 0.0 -0.237 15.0 15.0 NPHS1 0.007 0.045 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin 0.018 0.091 -9999.0 0.0 -0.254 16.0 16.0 TJP1 0.026 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.025 0.006 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.026 0.004 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.028 0.099 -9999.0 0.0 -0.271 15.0 15.0 CD2AP 0.027 0.002 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.03 0.1 -9999.0 0.0 -0.271 15.0 15.0 GRB2 0.026 0.005 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 0.001 0.106 0.296 8.0 -0.245 15.0 23.0 cytoskeleton organization -0.014 0.083 0.195 3.0 -0.28 13.0 16.0 Nephrin/NEPH1 0.016 0.068 0.157 2.0 -0.253 9.0 11.0 Nephrin/NEPH1/ZO-1 0.028 0.082 -9999.0 0.0 -0.292 9.0 9.0