Clinical Features Time to Death AGE NEOPLASM.DISEASESTAGE PATHOLOGY.T.STAGE PATHOLOGY.N.STAGE PATHOLOGY.M.STAGE GENDER HISTOLOGICAL.TYPE RADIATIONS.RADIATION.REGIMENINDICATION NUMBER.OF.LYMPH.NODES nMutated (%) nWild-Type logrank test_P logrank test_Q t-test_P t-test_Q Chi-square test_P Chi-square test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Chi-square test_P Chi-square test_Q Fisher's exact test_P Fisher's exact test_Q t-test_P t-test_Q PTEN 29 (4%) 742 0.57766 1 0.45792 1 0.0056126 1 0.42084 1 0.2781 1 0.061793 1 1 1 0.52341 1 0.83362 1 0.22125 1 MLL3 61 (8%) 710 0.45493 1 0.0096483 1 0.92252 1 0.68404 1 0.22225 1 0.51779 1 1 1 0.94293 1 0.23773 1 0.61976 1 NUDT11 8 (1%) 763 0.61511 1 0.57492 1 0.99754 1 0.41611 1 0.86793 1 0.040783 1 1 1 0.75022 1 1 1 0.5126 1 GIGYF2 13 (2%) 758 0.31319 1 0.64853 1 0.32767 1 0.0036696 1 0.059751 1 0.13636 1 1 1 0.91541 1 0.05766 1 0.96787 1 ZNF384 14 (2%) 757 0.33661 1 0.012719 1 0.43878 1 0.25976 1 0.42783 1 0.45297 1 1 1 0.91558 1 0.76733 1 1.1615e-05 0.0102 DCP1B 5 (1%) 766 0.53846 1 0.025035 1 0.99114 1 0.69002 1 0.77578 1 0.37503 1 1 1 0.9367 1 0.32917 1 0.44004 1 PIK3CA 261 (34%) 510 0.86485 1 0.023335 1 0.52326 1 0.79644 1 0.95064 1 0.35699 1 1 1 0.029875 1 1 1 0.33878 1 NCOA3 29 (4%) 742 0.67992 1 0.87512 1 0.56196 1 0.33534 1 0.35022 1 0.14162 1 1 1 0.47277 1 0.68065 1 0.17725 1 AOAH 19 (2%) 752 0.35247 1 0.4249 1 0.19717 1 0.051593 1 0.90704 1 0.27551 1 1 1 0.7795 1 0.11897 1 0.28164 1 RBMX 13 (2%) 758 0.70886 1 0.87351 1 0.9706 1 0.099994 1 0.40148 1 1 1 1 1 0.79946 1 0.53405 1 0.24084 1 RUNX1 25 (3%) 746 0.4446 1 0.60322 1 0.020824 1 0.12151 1 0.6539 1 1 1 1 1 0.057158 1 0.49833 1 0.53211 1 PIK3R1 21 (3%) 750 0.28298 1 0.68573 1 0.30008 1 0.068146 1 0.41056 1 0.48417 1 1 1 0.8322 1 1 1 0.080545 1 MEF2A 14 (2%) 757 0.24645 1 0.5219 1 0.41954 1 0.54092 1 0.37015 1 0.71896 1 1 1 0.02019 1 1 1 0.014186 1 NCOR2 29 (4%) 742 0.79344 1 0.70938 1 0.95674 1 0.43074 1 0.60545 1 0.37531 1 1 1 0.88397 1 1 1 0.2179 1 AKT1 19 (2%) 752 0.18211 1 0.13261 1 0.54092 1 0.32145 1 0.64568 1 0.59735 1 1 1 0.52301 1 0.11897 1 0.90221 1 GATA3 81 (11%) 690 0.61214 1 0.00021748 0.19 0.22917 1 0.0081679 1 0.66404 1 0.097873 1 0.59027 1 0.14525 1 0.151 1 0.59762 1 NR1H2 18 (2%) 753 0.14664 1 0.71377 1 0.0013087 1 0.27386 1 0.58935 1 0.002813 1 1 1 0.82309 1 0.79171 1 0.9544 1 MAP3K4 18 (2%) 753 0.5535 1 0.5425 1 0.78579 1 0.059787 1 0.78726 1 0.0014462 1 1 1 0.7423 1 0.79171 1 0.91235 1 TP53 257 (33%) 514 0.52856 1 0.038439 1 0.6548 1 0.064743 1 0.068731 1 0.055181 1 0.057442 1 9.9698e-07 0.000882 0.49751 1 0.41446 1 TPRX1 7 (1%) 764 0.61515 1 0.12309 1 0.79458 1 0.016453 1 1 1 0.48262 1 1 1 0.00236 1 0.41033 1 0.20473 1 CDH1 55 (7%) 716 0.55427 1 0.086132 1 0.14815 1 0.00034523 0.302 0.0051305 1 0.79896 1 1 1 4.4257e-69 3.93e-66 1 1 0.12922 1 ATN1 17 (2%) 754 0.34199 1 0.95926 1 0.83919 1 0.46614 1 0.7723 1 0.104 1 1 1 0.73313 1 0.4217 1 0.60901 1 MAP2K4 32 (4%) 739 0.17442 1 0.38629 1 0.97391 1 0.42116 1 0.46114 1 0.64718 1 1 1 0.54751 1 0.54791 1 0.91125 1 MAP3K1 57 (7%) 714 0.70695 1 0.00183 1 0.65178 1 0.1117 1 0.97563 1 0.56491 1 1 1 0.63418 1 1 1 7.2375e-07 0.000641 CBFB 16 (2%) 755 0.92935 1 0.72482 1 0.90741 1 0.20356 1 0.11795 1 0.20262 1 1 1 0.60674 1 1 1 0.82134 1 CTCF 18 (2%) 753 0.10061 1 0.93051 1 0.37916 1 0.12803 1 0.65537 1 0.57088 1 1 1 0.68054 1 0.79171 1 0.049822 1 CCDC144NL 8 (1%) 763 0.05176 1 0.050782 1 0.44953 1 0.48426 1 0.13501 1 1 1 1 1 0.96896 1 0.45243 1 0.29647 1 AKD1 19 (2%) 752 0.32474 1 0.46938 1 0.70645 1 0.18224 1 0.72247 1 0.27551 1 1 1 0.081636 1 0.44051 1 0.4373 1 RB1 14 (2%) 757 0.88478 1 0.12037 1 5.4842e-05 0.0483 0.52095 1 0.19719 1 0.71896 1 0.13695 1 0.92055 1 0.37058 1 0.4594 1 FOXA1 15 (2%) 756 0.013909 1 0.0024907 1 0.099748 1 0.0021431 1 0.87664 1 0.48419 1 1 1 0.0095942 1 0.25507 1 0.83253 1 PHLDA1 9 (1%) 762 0.028259 1 0.75169 1 0.22711 1 0.35648 1 0.79848 1 0.19849 1 1 1 0.68591 1 0.45773 1 0.00081744 0.713 VEZF1 8 (1%) 763 0.49175 1 0.087893 1 0.92274 1 0.91163 1 0.9276 1 0.52935 1 1 1 0.89042 1 0.23191 1 0.04249 1 ZFP36L1 10 (1%) 761 0.95785 1 0.012361 1 0.66154 1 0.59061 1 0.5315 1 0.22193 1 1 1 0.96197 1 0.070075 1 0.41018 1 NCOR1 31 (4%) 740 0.99621 1 0.93421 1 0.88949 1 0.81736 1 0.61863 1 0.34872 1 1 1 0.26911 1 0.68409 1 0.46214 1 AQP7 9 (1%) 762 0.0082237 1 0.48074 1 0.80261 1 0.54258 1 0.21481 1 1 1 1 1 0.96698 1 0.12716 1 0.15546 1 TBX3 18 (2%) 753 0.52237 1 0.015366 1 0.69107 1 0.59742 1 0.8835 1 0.57088 1 1 1 0.66913 1 0.79171 1 0.47153 1 DSPP 26 (3%) 745 0.59734 1 0.1665 1 0.83948 1 0.31374 1 0.65424 1 1 1 1 1 0.95227 1 1 1 0.375 1 RPGR 16 (2%) 755 0.99124 1 0.7635 1 0.90718 1 1 1 0.69546 1 0.27937 1 1 1 0.94279 1 0.40785 1 0.85061 1 BCL6B 8 (1%) 763 0.54664 1 0.74934 1 0.94278 1 0.38549 1 0.86793 1 0.040783 1 1 1 0.79965 1 0.11375 1 0.80537 1 TBL1XR1 9 (1%) 762 0.53981 1 0.022342 1 0.42169 1 0.082669 1 0.13835 1 0.19849 1 1 1 0.71223 1 0.71777 1 0.45371 1 CRIPAK 13 (2%) 758 0.95913 1 0.74642 1 0.95252 1 0.36425 1 0.092032 1 0.70738 1 0.12774 1 0.73679 1 1 1 0.21775 1 MYB 11 (1%) 760 0.16909 1 0.17983 1 0.78287 1 0.24015 1 0.87771 1 1 1 1 1 0.23975 1 0.51565 1 0.036372 1 GPS2 6 (1%) 765 0.20907 1 0.96634 1 0.10506 1 0.28442 1 0.056572 1 1 1 1 1 0.6781 1 0.67752 1 0.63823 1 PABPC3 8 (1%) 763 0.33911 1 0.94103 1 0.90881 1 0.74982 1 0.86793 1 1 1 0.080409 1 0.67866 1 1 1 0.16385 1 E2F4 4 (1%) 767 NA NA 0.36613 1 0.98229 1 0.13571 1 0.31449 1 1 1 1 1 0.46966 1 0.58169 1 NA NA DNAH12 12 (2%) 759 0.9825 1 0.97961 1 0.88206 1 0.28263 1 0.77452 1 0.67812 1 1 1 0.9439 1 0.33513 1 0.85962 1 CDKN1B 7 (1%) 764 0.85519 1 0.94501 1 0.051264 1 0.022161 1 0.0017284 1 0.02215 1 1 1 0.96696 1 1 1 0.047824 1 HNF1A 9 (1%) 762 0.39687 1 0.20482 1 0.98244 1 0.85053 1 0.40733 1 0.065371 1 1 1 0.0091167 1 0.2802 1 0.6364 1 CCDC66 14 (2%) 757 0.063883 1 0.667 1 0.95836 1 0.17607 1 0.65985 1 1 1 1 1 0.51273 1 1 1 0.6058 1 CASP8 10 (1%) 761 0.79337 1 0.58112 1 0.72394 1 0.92981 1 0.31314 1 0.61067 1 1 1 0.73248 1 0.29711 1 5.5688e-05 0.0489 STXBP2 10 (1%) 761 0.23047 1 0.063581 1 0.87502 1 0.92981 1 0.82156 1 1 1 1 1 0.96197 1 1 1 0.93479 1 HIST1H3B 7 (1%) 764 0.60303 1 0.28526 1 0.79458 1 0.38986 1 0.43374 1 1 1 1 1 0.91594 1 0.10379 1 0.45151 1 CTU2 5 (1%) 766 0.54225 1 0.56896 1 0.18722 1 0.25747 1 0.5937 1 1 1 1 1 0.0001159 0.102 0.32917 1 0.057974 1 TTN 122 (16%) 649 0.16093 1 0.0074754 1 0.025436 1 0.041169 1 0.74499 1 0.60748 1 0.36875 1 0.37299 1 0.91303 1 0.39874 1 SHROOM4 12 (2%) 759 0.19791 1 0.48078 1 0.95196 1 0.26934 1 0.31436 1 0.38744 1 0.11845 1 0.83278 1 0.10865 1 0.7862 1 HLA-A 4 (1%) 767 0.21471 1 0.43666 1 0.78941 1 1 1 0.36635 1 1 1 1 1 9.522e-06 0.00841 0.31785 1 0.58505 1 SLC25A5 3 (0%) 768 NA NA 0.52139 1 0.99931 1 0.38799 1 0.60738 1 0.24546 1 1 1 0.12996 1 1 1 0.93152 1 SELPLG 7 (1%) 764 0.58169 1 0.26628 1 0.80424 1 0.71623 1 0.84387 1 0.13398 1 1 1 0.96696 1 0.41033 1 0.00081744 0.713 KRTAP9-9 6 (1%) 765 0.54141 1 0.40808 1 0.92266 1 0.56504 1 0.388 1 0.43133 1 1 1 0.38204 1 0.35886 1 0.29265 1 KRTAP4-5 4 (1%) 767 0.57199 1 0.19439 1 0.90555 1 0.39511 1 0.14273 1 0.31325 1 1 1 0.29137 1 0.31785 1 0.46589 1 SF3B1 14 (2%) 757 0.23152 1 0.7398 1 0.23803 1 0.32604 1 0.8661 1 0.71896 1 1 1 0.86207 1 0.55364 1 0.77777 1 FGFR2 7 (1%) 764 0.0075843 1 0.75119 1 0.75615 1 0.12176 1 0.4671 1 0.13398 1 1 1 0.65436 1 0.67984 1 0.047101 1 MUC2 22 (3%) 749 0.66723 1 0.52001 1 0.40118 1 0.56309 1 0.20339 1 0.33157 1 0.20758 1 0.97626 1 0.090472 1 0.15281 1 MED12 20 (3%) 751 0.58331 1 0.77694 1 0.68053 1 0.52033 1 0.48458 1 0.36632 1 1 1 0.99058 1 0.21714 1 0.48946 1 USP36 13 (2%) 758 0.60107 1 0.07962 1 0.66548 1 0.48472 1 0.14535 1 0.13636 1 1 1 0.93295 1 0.37038 1 0.63361 1 DENND4B 8 (1%) 763 0.49443 1 0.73426 1 0.92561 1 0.48426 1 0.86793 1 0.52935 1 1 1 0.0038595 1 1 1 0.80643 1 RAI1 7 (1%) 764 0.56562 1 0.91721 1 0.38849 1 0.42493 1 0.84387 1 1 1 1 1 0.96696 1 0.41033 1 0.04819 1 ODF1 5 (1%) 766 0.093619 1 0.56876 1 0.59241 1 0.1063 1 0.37573 1 0.075083 1 1 1 4.1865e-05 0.0369 0.62505 1 0.96632 1 AXL 6 (1%) 765 0.02553 1 0.73394 1 0.61462 1 0.48534 1 0.10158 1 0.43133 1 1 1 0.0043135 1 0.192 1 0.44669 1 RPL18 4 (1%) 767 0.71446 1 0.85689 1 0.75454 1 0.77996 1 1 1 1 1 1 1 0.46966 1 0.31785 1 0.027042 1 KRT38 4 (1%) 767 0.47566 1 0.24206 1 0.99086 1 0.39511 1 0.49577 1 1 1 1 1 0.97444 1 0.31785 1 0.053852 1 ASXL2 8 (1%) 763 0.96792 1 0.94727 1 0.97566 1 0.74982 1 0.4173 1 1 1 1 1 0.96896 1 0.69381 1 7.0118e-05 0.0616 TICAM1 5 (1%) 766 0.54193 1 0.53967 1 0.071622 1 0.69002 1 0.017527 1 0.075083 1 1 1 0.95837 1 0.62505 1 0.72359 1 RBM5 12 (2%) 759 0.25191 1 0.86609 1 0.97958 1 0.34076 1 0.2306 1 1 1 1 1 0.30309 1 1 1 0.24493 1 ASPHD1 3 (0%) 768 0.03939 1 0.78241 1 0.96623 1 0.71944 1 0.77236 1 1 1 1 1 0.26795 1 0.56271 1 0.72735 1 PPEF1 8 (1%) 763 0.78307 1 0.70447 1 0.97927 1 1 1 0.37189 1 1 1 1 1 0.89042 1 1 1 0.16385 1 MUC20 10 (1%) 761 0.34926 1 0.16898 1 0.96719 1 0.49422 1 0.24843 1 0.61067 1 1 1 0.083929 1 0.48054 1 0.53279 1 TMEM184A 4 (1%) 767 0.90675 1 0.98098 1 0.99589 1 0.77996 1 0.11163 1 1 1 1 1 0.97444 1 0.58169 1 0.63248 1 FAM171B 8 (1%) 763 0.86451 1 0.0037456 1 0.85505 1 0.74982 1 0.9276 1 0.52935 1 0.080409 1 0.89042 1 0.69381 1 0.38324 1 PRRX1 6 (1%) 765 0.43898 1 0.90032 1 0.98977 1 0.75517 1 0.42458 1 1 1 1 1 0.93873 1 0.056891 1 0.72185 1 ATP13A4 9 (1%) 762 0.24781 1 0.54526 1 1.5407e-06 0.00136 0.85053 1 0.50076 1 1 1 1 1 0.86262 1 0.71777 1 0.055769 1 MUC21 6 (1%) 765 0.37157 1 0.46152 1 0.80202 1 0.35998 1 0.90369 1 1 1 1 1 0.93873 1 1 1 0.0026828 1 HLA-B 4 (1%) 767 0.64826 1 0.74397 1 0.98237 1 0.25993 1 0.7017 1 1 1 1 1 0.29137 1 1 1 0.79944 1 RBM23 6 (1%) 765 0.91537 1 0.74629 1 0.77786 1 0.052037 1 0.46446 1 0.10334 1 1 1 0.00038893 0.34 0.35886 1 0.79437 1 UBC 8 (1%) 763 0.20076 1 0.67052 1 0.93981 1 0.91163 1 0.81558 1 1 1 1 1 0.89042 1 1 1 0.84357 1 SPRED3 4 (1%) 767 0.76754 1 0.70682 1 0.97231 1 1 1 0.4209 1 1 1 1 1 0.88426 1 0.31785 1 0.69411 1 KCNN3 6 (1%) 765 0.63365 1 0.74417 1 0.67001 1 0.48534 1 0.8176 1 0.43133 1 1 1 0.2443 1 0.192 1 0.018978 1 GNRH2 3 (0%) 768 0.88095 1 0.17785 1 0.99931 1 1 1 0.11163 1 0.24546 1 1 1 0.75644 1 0.56271 1 0.43363 1 MED15 7 (1%) 764 0.38026 1 0.72101 1 0.25951 1 0.49956 1 0.84387 1 0.48262 1 0.070678 1 0.91594 1 1 1 7.0118e-05 0.0616