Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.089 0.194 0.645 97.0 -9999.0 0.0 97.0 KIRREL -0.08 0.242 -9999.0 0.0 -0.814 97.0 97.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.089 0.194 -9999.0 0.0 -0.646 97.0 97.0 PLCG1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.064 0.147 -9999.0 0.0 -0.495 97.0 97.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.039 0.108 -9999.0 0.0 -0.366 97.0 97.0 FYN -0.06 0.142 -9999.0 0.0 -0.474 97.0 97.0 mol:Ca2+ -0.064 0.146 -9999.0 0.0 -0.49 97.0 97.0 mol:DAG -0.064 0.147 -9999.0 0.0 -0.492 97.0 97.0 NPHS2 -0.009 0.028 -9999.0 0.0 -0.277 4.0 4.0 mol:IP3 -0.064 0.147 -9999.0 0.0 -0.492 97.0 97.0 regulation of endocytosis -0.032 0.14 -9999.0 0.0 -0.442 97.0 97.0 Nephrin/NEPH1/podocin/Cholesterol -0.067 0.15 -9999.0 0.0 -0.503 97.0 97.0 establishment of cell polarity -0.089 0.194 -9999.0 0.0 -0.645 97.0 97.0 Nephrin/NEPH1/podocin/NCK1-2 -0.052 0.136 -9999.0 0.0 -0.451 97.0 97.0 Nephrin/NEPH1/beta Arrestin2 -0.032 0.142 -9999.0 0.0 -0.448 97.0 97.0 NPHS1 -0.05 0.103 -9999.0 0.0 -0.279 162.0 162.0 Nephrin/NEPH1/podocin -0.055 0.145 -9999.0 0.0 -0.477 97.0 97.0 TJP1 -0.001 0.026 -9999.0 0.0 -0.807 1.0 1.0 NCK1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.064 0.147 -9999.0 0.0 -0.495 97.0 97.0 CD2AP -0.0 0.009 -9999.0 0.0 -0.279 1.0 1.0 Nephrin/NEPH1/podocin/GRB2 -0.064 0.148 -9999.0 0.0 -0.495 97.0 97.0 GRB2 -0.0 0.009 -9999.0 0.0 -0.279 1.0 1.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.068 0.163 -9999.0 0.0 -0.511 105.0 105.0 cytoskeleton organization -0.049 0.136 -9999.0 0.0 -0.459 97.0 97.0 Nephrin/NEPH1 -0.064 0.145 -9999.0 0.0 -0.486 97.0 97.0 Nephrin/NEPH1/ZO-1 -0.07 0.16 -9999.0 0.0 -0.536 97.0 97.0