Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.059 0.204 0.315 1.0 -0.399 170.0 171.0 MAP3K8 0.01 0.043 -9999.0 0.0 -0.582 4.0 4.0 FOS -0.022 0.144 0.319 2.0 -0.449 47.0 49.0 PRKCA -0.002 0.087 0.242 1.0 -0.584 20.0 21.0 PTPN7 0.02 0.06 0.252 52.0 -9999.0 0.0 52.0 HRAS 0.024 0.018 0.262 5.0 -9999.0 0.0 5.0 PRKCB 0.004 0.083 0.255 15.0 -0.583 15.0 30.0 NRAS 0.023 0.005 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.025 0.036 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 0.007 0.091 -9999.0 0.0 -0.802 5.0 5.0 MAP2K1 -0.012 0.119 -9999.0 0.0 -0.502 40.0 40.0 ELK1 0.006 0.029 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.013 0.102 -9999.0 0.0 -0.492 36.0 36.0 mol:GTP -0.002 0.003 -9999.0 0.0 -0.006 293.0 293.0 MAPK1 -0.011 0.125 -9999.0 0.0 -0.469 41.0 41.0 RAF1 -0.013 0.101 -9999.0 0.0 -0.488 36.0 36.0 KRAS 0.022 0.006 -9999.0 0.0 -9999.0 0.0 0.0