Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.085 0.19 0.438 31.0 -9999.0 0.0 31.0 KIRREL -0.078 0.216 -9999.0 0.0 -0.614 20.0 20.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.085 0.191 -9999.0 0.0 -0.439 31.0 31.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.069 0.136 -9999.0 0.0 -0.379 16.0 16.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.029 0.112 -9999.0 0.0 -0.453 2.0 2.0 FYN -0.056 0.136 -9999.0 0.0 -0.36 16.0 16.0 mol:Ca2+ -0.068 0.135 -9999.0 0.0 -0.376 16.0 16.0 mol:DAG -0.069 0.136 -9999.0 0.0 -0.377 16.0 16.0 NPHS2 -0.01 0.024 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.069 0.136 -9999.0 0.0 -0.377 16.0 16.0 regulation of endocytosis -0.045 0.129 -9999.0 0.0 -0.334 16.0 16.0 Nephrin/NEPH1/podocin/Cholesterol -0.071 0.139 -9999.0 0.0 -0.325 31.0 31.0 establishment of cell polarity -0.085 0.19 -9999.0 0.0 -0.438 31.0 31.0 Nephrin/NEPH1/podocin/NCK1-2 -0.041 0.133 -9999.0 0.0 -0.559 2.0 2.0 Nephrin/NEPH1/beta Arrestin2 -0.045 0.13 -9999.0 0.0 -0.338 16.0 16.0 NPHS1 -0.048 0.15 -9999.0 0.0 -0.522 13.0 13.0 Nephrin/NEPH1/podocin -0.056 0.136 -9999.0 0.0 -0.362 16.0 16.0 TJP1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.069 0.136 -9999.0 0.0 -0.379 16.0 16.0 CD2AP 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.069 0.136 -9999.0 0.0 -0.379 16.0 16.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.072 0.15 -9999.0 0.0 -0.361 19.0 19.0 cytoskeleton organization -0.034 0.133 -9999.0 0.0 -0.359 16.0 16.0 Nephrin/NEPH1 -0.059 0.139 -9999.0 0.0 -0.314 31.0 31.0 Nephrin/NEPH1/ZO-1 -0.074 0.148 -9999.0 0.0 -0.346 31.0 31.0