Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.031 0.143 0.422 14.0 -9999.0 0.0 14.0 KIRREL -0.049 0.183 -9999.0 0.0 -0.479 20.0 20.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.031 0.143 -9999.0 0.0 -0.423 14.0 14.0 PLCG1 0.025 0.007 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.025 0.008 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.025 0.007 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.003 0.119 -9999.0 0.0 -0.32 14.0 14.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.02 0.092 -9999.0 0.0 -0.283 14.0 14.0 FYN -0.025 0.117 0.252 7.0 -0.3 14.0 21.0 mol:Ca2+ -0.0 0.115 -9999.0 0.0 -0.319 13.0 13.0 mol:DAG 0.0 0.116 -9999.0 0.0 -0.32 13.0 13.0 NPHS2 -0.01 0.031 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 0.0 0.116 -9999.0 0.0 -0.32 13.0 13.0 regulation of endocytosis -0.005 0.105 -9999.0 0.0 -0.283 14.0 14.0 Nephrin/NEPH1/podocin/Cholesterol -0.012 0.113 -9999.0 0.0 -0.319 14.0 14.0 establishment of cell polarity -0.031 0.143 -9999.0 0.0 -0.422 14.0 14.0 Nephrin/NEPH1/podocin/NCK1-2 0.0 0.112 -9999.0 0.0 -0.295 14.0 14.0 Nephrin/NEPH1/beta Arrestin2 -0.004 0.106 -9999.0 0.0 -0.286 14.0 14.0 NPHS1 -0.021 0.068 -9999.0 0.0 -0.233 9.0 9.0 Nephrin/NEPH1/podocin -0.011 0.108 -9999.0 0.0 -0.302 14.0 14.0 TJP1 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.02 0.012 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.001 0.117 -9999.0 0.0 -0.322 13.0 13.0 CD2AP 0.026 0.007 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.005 0.119 -9999.0 0.0 -0.321 14.0 14.0 GRB2 0.025 0.007 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.037 0.12 0.269 6.0 -0.299 16.0 22.0 cytoskeleton organization -0.025 0.109 0.205 1.0 -0.321 14.0 15.0 Nephrin/NEPH1 -0.017 0.103 -9999.0 0.0 -0.3 14.0 14.0 Nephrin/NEPH1/ZO-1 -0.009 0.122 -9999.0 0.0 -0.342 14.0 14.0