Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.048 0.172 0.518 27.0 -9999.0 0.0 27.0 KIRREL 0.005 0.02 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.048 0.173 -9999.0 0.0 -0.519 27.0 27.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.028 0.141 -9999.0 0.0 -0.391 29.0 29.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.005 0.085 -9999.0 0.0 -0.45 1.0 1.0 FYN -0.029 0.124 -9999.0 0.0 -0.348 29.0 29.0 mol:Ca2+ -0.029 0.139 -9999.0 0.0 -0.388 29.0 29.0 mol:DAG -0.028 0.14 -9999.0 0.0 -0.389 29.0 29.0 NPHS2 -0.01 0.083 -9999.0 0.0 -0.712 3.0 3.0 mol:IP3 -0.028 0.14 -9999.0 0.0 -0.389 29.0 29.0 regulation of endocytosis -0.018 0.118 -9999.0 0.0 -0.323 29.0 29.0 Nephrin/NEPH1/podocin/Cholesterol -0.036 0.14 -9999.0 0.0 -0.397 29.0 29.0 establishment of cell polarity -0.048 0.172 -9999.0 0.0 -0.518 27.0 27.0 Nephrin/NEPH1/podocin/NCK1-2 -0.018 0.13 -9999.0 0.0 -0.354 29.0 29.0 Nephrin/NEPH1/beta Arrestin2 -0.018 0.12 -9999.0 0.0 -0.327 29.0 29.0 NPHS1 -0.071 0.226 -9999.0 0.0 -0.693 27.0 27.0 Nephrin/NEPH1/podocin -0.027 0.125 -9999.0 0.0 -0.35 29.0 29.0 TJP1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.028 0.141 -9999.0 0.0 -0.391 29.0 29.0 CD2AP 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.028 0.141 -9999.0 0.0 -0.391 29.0 29.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.029 0.129 -9999.0 0.0 -0.355 30.0 30.0 cytoskeleton organization -0.009 0.108 -9999.0 0.0 -0.389 3.0 3.0 Nephrin/NEPH1 -0.033 0.126 -9999.0 0.0 -0.378 27.0 27.0 Nephrin/NEPH1/ZO-1 -0.03 0.142 -9999.0 0.0 -0.417 27.0 27.0