Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.075 0.182 0.397 69.0 -9999.0 0.0 69.0 KIRREL -0.046 0.179 -9999.0 0.0 -0.653 25.0 25.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.075 0.183 -9999.0 0.0 -0.398 69.0 69.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.052 0.149 -9999.0 0.0 -0.408 34.0 34.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.026 0.118 -9999.0 0.0 -0.333 32.0 32.0 FYN -0.052 0.144 -9999.0 0.0 -0.39 36.0 36.0 mol:Ca2+ -0.069 0.138 -9999.0 0.0 -0.404 34.0 34.0 mol:DAG -0.07 0.138 -9999.0 0.0 -0.406 34.0 34.0 NPHS2 -0.022 0.091 -9999.0 0.0 -0.449 13.0 13.0 mol:IP3 -0.07 0.138 -9999.0 0.0 -0.406 34.0 34.0 regulation of endocytosis -0.041 0.137 -9999.0 0.0 -0.362 36.0 36.0 Nephrin/NEPH1/podocin/Cholesterol -0.059 0.148 -9999.0 0.0 -0.415 34.0 34.0 establishment of cell polarity -0.075 0.182 -9999.0 0.0 -0.397 69.0 69.0 Nephrin/NEPH1/podocin/NCK1-2 -0.038 0.137 -9999.0 0.0 -0.387 26.0 26.0 Nephrin/NEPH1/beta Arrestin2 -0.041 0.139 -9999.0 0.0 -0.367 36.0 36.0 NPHS1 -0.066 0.176 -9999.0 0.0 -0.474 47.0 47.0 Nephrin/NEPH1/podocin -0.052 0.145 -9999.0 0.0 -0.392 36.0 36.0 TJP1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.051 0.148 -9999.0 0.0 -0.408 34.0 34.0 CD2AP 0.011 0.025 -9999.0 0.0 -0.428 1.0 1.0 Nephrin/NEPH1/podocin/GRB2 -0.051 0.148 -9999.0 0.0 -0.408 34.0 34.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.061 0.167 -9999.0 0.0 -0.444 38.0 38.0 cytoskeleton organization -0.032 0.142 -9999.0 0.0 -0.399 32.0 32.0 Nephrin/NEPH1 -0.051 0.133 -9999.0 0.0 -0.372 34.0 34.0 Nephrin/NEPH1/ZO-1 -0.068 0.141 -9999.0 0.0 -0.418 32.0 32.0