Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.036 0.2 -9999.0 0.0 -0.688 19.0 19.0 MAP3K8 0.01 0.037 -9999.0 0.0 -0.648 1.0 1.0 FOS -0.037 0.187 -9999.0 0.0 -0.636 21.0 21.0 PRKCA 0.007 0.058 -9999.0 0.0 -0.574 3.0 3.0 PTPN7 -0.059 0.186 -9999.0 0.0 -0.517 43.0 43.0 HRAS 0.011 0.025 -9999.0 0.0 -0.428 1.0 1.0 PRKCB -0.065 0.199 -9999.0 0.0 -0.556 43.0 43.0 NRAS 0.012 0.001 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.022 0.02 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.031 0.166 -9999.0 0.0 -0.657 17.0 17.0 MAP2K1 -0.016 0.138 -9999.0 0.0 -0.445 27.0 27.0 ELK1 0.012 0.005 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.023 0.136 -9999.0 0.0 -0.448 27.0 27.0 mol:GTP -0.0 0.001 -9999.0 0.0 -0.005 24.0 24.0 MAPK1 -0.031 0.166 -9999.0 0.0 -0.615 19.0 19.0 RAF1 -0.023 0.136 -9999.0 0.0 -0.448 27.0 27.0 KRAS 0.011 0.025 -9999.0 0.0 -0.428 1.0 1.0