Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.024 0.137 0.419 28.0 -9999.0 0.0 28.0 KIRREL -0.019 0.147 -9999.0 0.0 -0.538 23.0 23.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.024 0.137 -9999.0 0.0 -0.419 28.0 28.0 PLCG1 0.015 0.012 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.021 0.009 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.024 0.005 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.024 0.115 -9999.0 0.0 -0.324 27.0 27.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.007 0.091 -9999.0 0.0 -0.287 26.0 26.0 FYN -0.024 0.108 0.26 6.0 -0.307 29.0 35.0 mol:Ca2+ 0.005 0.105 -9999.0 0.0 -0.326 23.0 23.0 mol:DAG 0.005 0.106 -9999.0 0.0 -0.327 23.0 23.0 NPHS2 -0.0 0.049 -9999.0 0.0 -0.192 13.0 13.0 mol:IP3 0.005 0.106 -9999.0 0.0 -0.327 23.0 23.0 regulation of endocytosis 0.009 0.106 -9999.0 0.0 -0.287 29.0 29.0 Nephrin/NEPH1/podocin/Cholesterol 0.001 0.111 -9999.0 0.0 -0.313 29.0 29.0 establishment of cell polarity -0.024 0.137 -9999.0 0.0 -0.419 28.0 28.0 Nephrin/NEPH1/podocin/NCK1-2 0.039 0.111 -9999.0 0.0 -0.298 27.0 27.0 Nephrin/NEPH1/beta Arrestin2 0.011 0.108 -9999.0 0.0 -0.29 29.0 29.0 NPHS1 -0.02 0.113 -9999.0 0.0 -0.461 12.0 12.0 Nephrin/NEPH1/podocin 0.012 0.111 -9999.0 0.0 -0.305 30.0 30.0 TJP1 0.024 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.025 0.002 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.025 0.001 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.006 0.107 -9999.0 0.0 -0.329 23.0 23.0 CD2AP 0.025 0.002 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.024 0.115 -9999.0 0.0 -0.323 27.0 27.0 GRB2 0.025 0.003 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.031 0.124 0.268 5.0 -0.353 31.0 36.0 cytoskeleton organization -0.023 0.106 0.205 1.0 -0.344 26.0 27.0 Nephrin/NEPH1 -0.012 0.099 -9999.0 0.0 -0.298 28.0 28.0 Nephrin/NEPH1/ZO-1 -0.005 0.116 -9999.0 0.0 -0.336 28.0 28.0