Clinical Features Time to Death AGE NEOPLASM.DISEASESTAGE PATHOLOGY.T.STAGE PATHOLOGY.N.STAGE GENDER RADIATIONS.RADIATION.REGIMENINDICATION NUMBERPACKYEARSSMOKED YEAROFTOBACCOSMOKINGONSET NUMBER.OF.LYMPH.NODES nMutated (%) nWild-Type logrank test_P logrank test_Q t-test_P t-test_Q Chi-square test_P Chi-square test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q t-test_P t-test_Q t-test_P t-test_Q t-test_P t-test_Q POLDIP2 6 (2%) 300 0.70301 1 0.03791 1 0.14162 1 0.15949 1 0.31515 1 1 1 0.34551 1 0.9695 1 0.013534 1 0.0007192 0.329 NSD1 33 (11%) 273 0.097417 1 0.081895 1 0.057652 1 0.77834 1 0.00053645 0.246 0.30097 1 0.30351 1 0.20971 1 0.94022 1 0.00025641 0.118 NUDT11 6 (2%) 300 0.89104 1 0.99217 1 0.67044 1 1 1 0.66757 1 0.19339 1 1 1 0.31276 1 NA NA 0.2873 1 PIK3CA 64 (21%) 242 0.25937 1 0.83191 1 0.48974 1 0.74154 1 0.4651 1 0.11444 1 1 1 0.70863 1 0.91716 1 0.38025 1 CDKN2A 66 (22%) 240 0.58595 1 0.68105 1 0.32365 1 0.66474 1 0.97074 1 0.87632 1 0.63554 1 0.080721 1 0.405 1 0.92846 1 HRAS 10 (3%) 296 0.067577 1 0.22718 1 0.097498 1 0.24136 1 0.048592 1 1 1 0.46335 1 0.14576 1 0.21563 1 0.21109 1 TP53 214 (70%) 92 1.4494e-05 0.00671 0.76941 1 0.0079548 1 0.0057709 1 0.015604 1 0.781 1 0.47823 1 0.10917 1 0.79775 1 0.020092 1 NFE2L2 17 (6%) 289 0.093441 1 0.006976 1 0.69861 1 0.772 1 1 1 0.26064 1 0.25535 1 0.91697 1 0.30767 1 0.67695 1 NOTCH1 59 (19%) 247 0.45717 1 0.14158 1 0.83187 1 0.786 1 0.82237 1 0.25555 1 0.32292 1 0.0095465 1 0.82387 1 0.1582 1 FAT1 72 (24%) 234 0.52066 1 0.00051048 0.235 0.60978 1 0.5369 1 0.79161 1 0.13132 1 1 1 0.50868 1 0.12959 1 0.86661 1 CASP8 27 (9%) 279 0.83136 1 0.00030258 0.139 0.26553 1 0.55929 1 0.085232 1 0.0012748 0.583 0.49152 1 0.22877 1 0.13032 1 0.094231 1 MLL2 56 (18%) 250 0.7423 1 0.99327 1 0.27135 1 0.24243 1 0.89255 1 0.86888 1 0.40604 1 0.38099 1 0.35662 1 0.069122 1 JUB 18 (6%) 288 0.1804 1 0.080219 1 0.70935 1 0.45514 1 0.29628 1 1 1 1 1 0.51861 1 0.064861 1 0.92877 1 FBXW7 15 (5%) 291 0.68732 1 0.095829 1 0.47162 1 0.63464 1 0.29511 1 0.37184 1 1 1 0.40518 1 0.37086 1 0.37254 1 EPHA2 14 (5%) 292 0.046258 1 0.89069 1 0.64933 1 0.93162 1 0.18799 1 0.22052 1 1 1 0.007736 1 0.060029 1 0.34216 1 ZNF750 13 (4%) 293 0.8476 1 0.84527 1 0.47754 1 0.059409 1 0.74897 1 0.12301 1 0.52553 1 0.91734 1 0.15965 1 0.76666 1 FLG 48 (16%) 258 0.94746 1 0.60469 1 0.67005 1 0.59926 1 0.073631 1 1 1 0.59529 1 0.78537 1 0.44921 1 0.35334 1 B2M 7 (2%) 299 0.22912 1 0.48302 1 0.874 1 0.60968 1 NA NA 1 1 0.68077 1 NA NA NA NA NA NA HLA-A 14 (5%) 292 0.92007 1 0.59042 1 0.96289 1 0.49118 1 0.9325 1 1 1 0.056941 1 0.64252 1 0.73148 1 0.0028418 1 EP300 25 (8%) 281 0.46926 1 0.53598 1 0.76985 1 0.95093 1 0.60569 1 0.64122 1 1 1 0.11954 1 0.72563 1 0.53342 1 IL32 4 (1%) 302 0.13225 1 0.93188 1 0.010687 1 0.87804 1 0.065005 1 0.30318 1 0.57601 1 NA NA NA NA 0.80224 1 RHOA 4 (1%) 302 0.29892 1 0.91598 1 0.84309 1 0.22387 1 0.4064 1 0.30318 1 0.57601 1 0.0020312 0.926 0.54525 1 0.14752 1 CTCF 11 (4%) 295 0.54302 1 0.044362 1 0.46794 1 0.93475 1 0.65847 1 0.1811 1 0.4863 1 0.15524 1 0.19028 1 0.24432 1 RB1 10 (3%) 296 0.23255 1 0.71352 1 0.093847 1 0.24021 1 0.66757 1 0.14455 1 1 1 0.86004 1 0.64585 1 0.77207 1 CSMD3 70 (23%) 236 0.87122 1 0.97283 1 0.045204 1 0.20241 1 0.0052844 1 1 1 1 1 0.07992 1 0.50269 1 0.34815 1 TGFBR2 10 (3%) 296 0.79891 1 0.029202 1 0.8862 1 0.71046 1 0.34082 1 0.4703 1 0.068374 1 0.28491 1 0.008368 1 0.046366 1 NECAB1 6 (2%) 300 0.81197 1 0.0099894 1 0.60661 1 0.51704 1 1 1 0.35132 1 1 1 0.8153 1 0.042274 1 0.2873 1 MAPK1 4 (1%) 302 0.41928 1 0.29173 1 0.55341 1 0.51374 1 0.56165 1 1 1 0.57601 1 NA NA NA NA 0.99301 1 PLSCR1 5 (2%) 301 0.074285 1 0.39542 1 0.76191 1 0.83411 1 0.43155 1 1 1 1 1 NA NA 0.30264 1 0.91339 1 CNPY3 3 (1%) 303 0.7537 1 0.080726 1 0.68788 1 0.84023 1 1 1 0.56424 1 1 1 0.89067 1 0.097938 1 0.5409 1 EPB41L3 16 (5%) 290 0.79449 1 0.8403 1 0.66611 1 0.84597 1 0.9325 1 0.15268 1 0.7702 1 0.37223 1 0.64862 1 0.041731 1 RAC1 9 (3%) 297 0.60176 1 0.0068215 1 0.55717 1 0.41172 1 0.2173 1 0.067629 1 1 1 0.73194 1 0.0047837 1 0.029331 1 RANGAP1 4 (1%) 302 0.49056 1 0.71303 1 0.0096916 1 0.023562 1 1 1 0.0053867 1 0.57601 1 NA NA NA NA 0.21205 1 ZCCHC3 5 (2%) 301 0.39709 1 0.46483 1 0.44607 1 0.26884 1 0.60686 1 0.12926 1 0.60866 1 0.31633 1 0.74647 1 0.95655 1 CUL3 10 (3%) 296 0.60038 1 0.46673 1 0.36444 1 0.087536 1 0.42284 1 0.73291 1 0.13445 1 0.541 1 0.19505 1 0.98363 1 PRB2 10 (3%) 296 0.79521 1 0.63917 1 0.50682 1 0.22722 1 0.65847 1 0.067011 1 0.46335 1 0.23316 1 0.84681 1 0.47149 1 PRB1 7 (2%) 299 0.40851 1 0.52816 1 0.68334 1 0.61772 1 0.45891 1 0.19597 1 0.079215 1 0.25502 1 0.86609 1 0.98081 1 TRPV4 7 (2%) 299 0.056291 1 0.78612 1 0.91737 1 1 1 0.30188 1 0.67818 1 0.3831 1 0.7182 1 NA NA 0.60568 1 WHSC1 10 (3%) 296 0.12113 1 0.46921 1 0.75757 1 0.19009 1 0.35729 1 0.73291 1 0.72476 1 0.080311 1 0.7821 1 0.02813 1 EPDR1 6 (2%) 300 0.45225 1 0.80465 1 0.67044 1 0.58691 1 0.26796 1 0.66766 1 0.65364 1 0.9055 1 0.1674 1 0.32646 1 KCNA3 8 (3%) 298 0.25087 1 0.19953 1 0.47401 1 0.56786 1 1 1 0.22168 1 1 1 0.79041 1 0.52849 1 0.5024 1 HIST1H1B 7 (2%) 299 0.26745 1 0.085667 1 0.22256 1 0.89767 1 0.1307 1 0.39772 1 0.68077 1 NA NA NA NA 0.49615 1 STEAP4 10 (3%) 296 0.1014 1 0.98136 1 0.76839 1 0.12984 1 1 1 0.29502 1 0.46335 1 0.037554 1 0.36042 1 0.66883 1 SLC26A7 8 (3%) 298 0.31988 1 0.12583 1 0.3503 1 0.70122 1 0.68761 1 0.68858 1 0.43508 1 0.23179 1 0.13542 1 0.028178 1 FCRL4 13 (4%) 293 0.33325 1 0.22332 1 0.66428 1 0.25448 1 0.55794 1 0.52597 1 1 1 0.10717 1 0.086826 1 0.88976 1 OR8D4 6 (2%) 300 0.3525 1 0.1317 1 0.63187 1 0.76249 1 0.43155 1 1 1 1 1 0.79269 1 0.26218 1 0.15448 1 TXK 3 (1%) 303 0.54694 1 0.53801 1 0.68788 1 0.32801 1 1 1 1 1 0.1684 1 NA NA NA NA 0.96599 1 POU4F2 7 (2%) 299 0.29184 1 0.35434 1 0.090464 1 0.086889 1 0.26796 1 0.19597 1 1 1 0.45252 1 0.72728 1 0.97634 1