Clinical Features Time to Death AGE NEOPLASM.DISEASESTAGE PATHOLOGY.T.STAGE PATHOLOGY.N.STAGE PATHOLOGY.M.STAGE GENDER KARNOFSKY.PERFORMANCE.SCORE NUMBERPACKYEARSSMOKED YEAROFTOBACCOSMOKINGONSET nCNV (%) nWild-Type logrank test_P logrank test_Q t-test_P t-test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q t-test_P t-test_Q t-test_P t-test_Q t-test_P t-test_Q 3P GAIN MUTATION ANALYSIS 8 (12%) 56 0.0025389 1 0.065749 1 0.014625 1 0.46024 1 0.032692 1 0.26909 1 0.1349 1 NA NA NA NA NA NA 3Q GAIN MUTATION ANALYSIS 8 (12%) 56 0.0025389 1 0.065749 1 0.014625 1 0.46024 1 0.032692 1 0.26909 1 0.1349 1 NA NA NA NA NA NA 4P GAIN MUTATION ANALYSIS 19 (30%) 45 0.25962 1 0.57486 1 0.1409 1 0.94087 1 1 1 0.12736 1 0.57652 1 0.8631 1 0.073 1 0.008403 1 4Q GAIN MUTATION ANALYSIS 18 (28%) 46 0.25962 1 0.90187 1 0.14358 1 1 1 1 1 0.12736 1 0.7763 1 0.8631 1 0.073 1 0.008403 1 5P GAIN MUTATION ANALYSIS 7 (11%) 57 0.00042021 0.205 0.10495 1 0.00092563 0.446 0.27802 1 0.087416 1 0.0090268 1 0.69547 1 NA NA NA NA NA NA 5Q GAIN MUTATION ANALYSIS 7 (11%) 57 0.00042021 0.205 0.10495 1 0.00092563 0.446 0.27802 1 0.087416 1 0.0090268 1 0.69547 1 NA NA NA NA NA NA 7P GAIN MUTATION ANALYSIS 23 (36%) 41 0.01878 1 0.26399 1 0.1055 1 0.54657 1 0.15532 1 0.10661 1 0.18131 1 0.8631 1 0.55062 1 0.034133 1 7Q GAIN MUTATION ANALYSIS 23 (36%) 41 0.01878 1 0.26399 1 0.1055 1 0.54657 1 0.15532 1 0.10661 1 0.18131 1 0.8631 1 0.55062 1 0.034133 1 8P GAIN MUTATION ANALYSIS 15 (23%) 49 0.60593 1 0.20221 1 0.61291 1 0.66125 1 0.63945 1 0.48228 1 0.36759 1 0.8631 1 0.83047 1 NA NA 8Q GAIN MUTATION ANALYSIS 16 (25%) 48 0.60593 1 0.21113 1 0.32929 1 0.6708 1 0.63945 1 0.069918 1 0.24252 1 0.8631 1 0.83047 1 NA NA 9P GAIN MUTATION ANALYSIS 10 (16%) 54 0.40377 1 0.9577 1 0.085184 1 0.16253 1 0.30573 1 1 1 1 1 NA NA 0.56621 1 NA NA 9Q GAIN MUTATION ANALYSIS 10 (16%) 54 0.40377 1 0.9577 1 0.085184 1 0.16253 1 0.30573 1 1 1 1 1 NA NA 0.56621 1 NA NA 11P GAIN MUTATION ANALYSIS 14 (22%) 50 0.57465 1 0.84578 1 0.6085 1 0.69695 1 0.61737 1 0.36658 1 1 1 NA NA 0.073 1 0.008403 1 11Q GAIN MUTATION ANALYSIS 15 (23%) 49 0.57465 1 0.86574 1 0.27873 1 0.70795 1 0.61737 1 0.052904 1 0.76473 1 NA NA 0.073 1 0.008403 1 12P GAIN MUTATION ANALYSIS 17 (27%) 47 0.71423 1 0.031938 1 0.38491 1 0.88071 1 1 1 0.093869 1 0.39709 1 0.8631 1 0.83047 1 NA NA 12Q GAIN MUTATION ANALYSIS 17 (27%) 47 0.16723 1 0.095561 1 0.13837 1 0.93843 1 0.31462 1 0.093869 1 0.39709 1 0.8631 1 0.47279 1 0.008403 1 14Q GAIN MUTATION ANALYSIS 17 (27%) 47 0.80562 1 0.2758 1 0.25627 1 0.35615 1 0.65108 1 0.67085 1 0.77845 1 0.8631 1 0.47279 1 0.008403 1 15Q GAIN MUTATION ANALYSIS 18 (28%) 46 0.34385 1 0.82128 1 0.74302 1 0.73536 1 1 1 0.69498 1 1 1 0.8631 1 0.36808 1 0.16097 1 16P GAIN MUTATION ANALYSIS 18 (28%) 46 0.50094 1 0.69263 1 0.4953 1 0.44423 1 0.64111 1 0.69498 1 1 1 0.8631 1 0.073 1 0.008403 1 16Q GAIN MUTATION ANALYSIS 18 (28%) 46 0.50094 1 0.69263 1 0.4953 1 0.44423 1 0.64111 1 0.69498 1 1 1 0.8631 1 0.073 1 0.008403 1 18P GAIN MUTATION ANALYSIS 14 (22%) 50 0.59066 1 0.42745 1 0.39881 1 0.64831 1 0.31308 1 0.33699 1 0.53705 1 NA NA 0.74498 1 NA NA 18Q GAIN MUTATION ANALYSIS 13 (20%) 51 0.6991 1 0.75524 1 0.49711 1 0.33884 1 0.31308 1 0.33699 1 0.54382 1 NA NA 0.74498 1 NA NA 19P GAIN MUTATION ANALYSIS 17 (27%) 47 0.00091415 0.442 0.057484 1 0.015845 1 0.52664 1 0.0024579 1 0.069918 1 0.39709 1 NA NA 0.55062 1 0.034133 1 19Q GAIN MUTATION ANALYSIS 16 (25%) 48 0.01373 1 0.027403 1 0.10674 1 0.71873 1 0.027037 1 0.036579 1 0.56101 1 NA NA 0.36808 1 0.16097 1 20P GAIN MUTATION ANALYSIS 18 (28%) 46 0.35272 1 0.26082 1 0.42773 1 0.94105 1 0.35044 1 0.69498 1 0.7763 1 0.8631 1 0.47279 1 0.008403 1 20Q GAIN MUTATION ANALYSIS 18 (28%) 46 0.28768 1 0.21853 1 0.14358 1 1 1 0.33007 1 0.69498 1 0.7763 1 0.8631 1 0.073 1 0.008403 1 21Q GAIN MUTATION ANALYSIS 3 (5%) 61 0.60359 1 0.85292 1 1 1 1 1 NA NA NA NA 0.55537 1 NA NA NA NA NA NA 22Q GAIN MUTATION ANALYSIS 17 (27%) 47 0.028714 1 0.73336 1 0.52084 1 0.52664 1 0.16558 1 0.33994 1 0.39709 1 NA NA 0.55062 1 0.034133 1 XQ GAIN MUTATION ANALYSIS 10 (16%) 54 0.33463 1 0.15923 1 0.19085 1 0.75625 1 1 1 0.16721 1 0.29203 1 NA NA NA NA NA NA 1P LOSS MUTATION ANALYSIS 47 (73%) 17 0.44689 1 0.05925 1 0.037619 1 0.14833 1 1 1 0.067111 1 0.15533 1 0.37414 1 0.66059 1 0.30846 1 1Q LOSS MUTATION ANALYSIS 47 (73%) 17 0.81617 1 0.062981 1 0.04614 1 0.094956 1 1 1 0.096386 1 0.15533 1 0.37414 1 0.16394 1 0.30846 1 2P LOSS MUTATION ANALYSIS 42 (66%) 22 0.48756 1 0.056398 1 0.24129 1 0.19715 1 1 1 0.37241 1 0.18792 1 0.37414 1 0.16394 1 0.30846 1 2Q LOSS MUTATION ANALYSIS 42 (66%) 22 0.48756 1 0.056398 1 0.24129 1 0.19715 1 1 1 0.37241 1 0.18792 1 0.37414 1 0.16394 1 0.30846 1 3P LOSS MUTATION ANALYSIS 7 (11%) 57 0.35304 1 0.19495 1 0.2179 1 0.08296 1 1 1 1 1 0.41743 1 NA NA NA NA NA NA 3Q LOSS MUTATION ANALYSIS 6 (9%) 58 0.40905 1 0.37016 1 0.3373 1 0.17451 1 1 1 NA NA 0.19854 1 NA NA NA NA NA NA 5P LOSS MUTATION ANALYSIS 6 (9%) 58 0.61749 1 0.00073596 0.357 0.1662 1 0.1497 1 0.38662 1 0.45458 1 0.67088 1 NA NA NA NA NA NA 5Q LOSS MUTATION ANALYSIS 6 (9%) 58 0.61749 1 0.00073596 0.357 0.1662 1 0.1497 1 0.38662 1 0.45458 1 0.67088 1 NA NA NA NA NA NA 6P LOSS MUTATION ANALYSIS 46 (72%) 18 0.17817 1 0.074546 1 0.14575 1 0.088681 1 1 1 0.21031 1 0.097235 1 0.37414 1 0.16394 1 0.30846 1 6Q LOSS MUTATION ANALYSIS 47 (73%) 17 0.17817 1 0.084343 1 0.14938 1 0.094956 1 0.57144 1 0.21031 1 0.15533 1 0.37414 1 0.16394 1 0.30846 1 8P LOSS MUTATION ANALYSIS 10 (16%) 54 0.23319 1 0.88759 1 0.5817 1 0.31609 1 1 1 1 1 1 1 NA NA NA NA NA NA 8Q LOSS MUTATION ANALYSIS 9 (14%) 55 0.27057 1 0.76653 1 0.68361 1 0.4351 1 1 1 1 1 0.72753 1 NA NA NA NA NA NA 9P LOSS MUTATION ANALYSIS 6 (9%) 58 0.034242 1 0.15992 1 0.58108 1 0.42383 1 0.38662 1 1 1 0.39053 1 NA NA NA NA NA NA 9Q LOSS MUTATION ANALYSIS 7 (11%) 57 0.088163 1 0.34099 1 0.28967 1 0.23659 1 0.46143 1 1 1 0.69547 1 NA NA NA NA NA NA 10P LOSS MUTATION ANALYSIS 45 (70%) 19 0.19208 1 0.43224 1 0.42189 1 0.31288 1 1 1 0.023261 1 0.57652 1 0.10664 1 NA NA NA NA 10Q LOSS MUTATION ANALYSIS 45 (70%) 19 0.19208 1 0.43224 1 0.42189 1 0.31288 1 1 1 0.023261 1 0.57652 1 0.10664 1 NA NA NA NA 11P LOSS MUTATION ANALYSIS 7 (11%) 57 0.39068 1 0.02257 1 0.087725 1 0.050229 1 0.46143 1 1 1 0.69547 1 NA NA NA NA NA NA 11Q LOSS MUTATION ANALYSIS 7 (11%) 57 0.39068 1 0.02257 1 0.087725 1 0.050229 1 0.46143 1 1 1 0.69547 1 NA NA NA NA NA NA 13Q LOSS MUTATION ANALYSIS 40 (62%) 24 0.064029 1 0.010018 1 0.34108 1 0.24394 1 0.15262 1 0.62828 1 0.1122 1 0.8099 1 0.055629 1 1 1 16P LOSS MUTATION ANALYSIS 4 (6%) 60 2.7084e-10 1.33e-07 0.46566 1 0.00046429 0.226 0.0076254 1 3.3558e-05 0.0164 NA NA 1 1 NA NA NA NA NA NA 16Q LOSS MUTATION ANALYSIS 5 (8%) 59 2.3467e-10 1.15e-07 0.19896 1 0.0049503 1 0.037075 1 0.00016452 0.0804 NA NA 0.64041 1 NA NA NA NA NA NA 17P LOSS MUTATION ANALYSIS 46 (72%) 18 0.76441 1 0.044869 1 0.030463 1 0.022795 1 1 1 0.17843 1 0.097235 1 0.37414 1 NA NA NA NA 17Q LOSS MUTATION ANALYSIS 46 (72%) 18 0.76441 1 0.044869 1 0.030463 1 0.022795 1 1 1 0.17843 1 0.097235 1 0.37414 1 NA NA NA NA 18P LOSS MUTATION ANALYSIS 6 (9%) 58 0.68451 1 0.97013 1 0.26885 1 0.58214 1 0.12482 1 0.63828 1 0.19854 1 NA NA NA NA NA NA 18Q LOSS MUTATION ANALYSIS 8 (12%) 56 0.18003 1 0.59499 1 0.085421 1 0.57161 1 0.16625 1 0.63828 1 0.24461 1 NA NA NA NA NA NA 20P LOSS MUTATION ANALYSIS 4 (6%) 60 0.44185 1 0.17213 1 0.16154 1 0.10993 1 0.30374 1 1 1 0.64041 1 NA NA NA NA NA NA 20Q LOSS MUTATION ANALYSIS 3 (5%) 61 0.31273 1 0.42303 1 0.043203 1 0.027362 1 0.30374 1 1 1 1 1 NA NA NA NA NA NA 21Q LOSS MUTATION ANALYSIS 32 (50%) 32 0.091283 1 0.89747 1 0.71681 1 0.54634 1 0.063358 1 0.10013 1 1 1 0.27781 1 0.28013 1 0.10126 1 22Q LOSS MUTATION ANALYSIS 8 (12%) 56 0.17954 1 0.54183 1 0.12007 1 0.71643 1 0.16625 1 0.34173 1 0.048029 1 NA NA NA NA NA NA XQ LOSS MUTATION ANALYSIS 40 (62%) 24 0.31048 1 0.34958 1 0.23312 1 0.24394 1 1 1 0.14137 1 0.29119 1 0.079055 1 0.039808 1 0.27686 1