num gene desc n mindist nmuts0 nmuts3 nmuts12 npairs0 npairs3 npairs12 2309 TP53 tumor protein p53 27 0 3 9 43 3 9 43 664 EBPL emopamil binding protein-like 4 0 2 2 6 2 2 6 1386 MUC4 mucin 4, cell surface associated 13 0 1 1 2 1 1 2 26 ACR acrosin 2 0 1 1 1 1 1 1 180 ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4 2 0 1 1 1 1 1 1 239 C10orf120 chromosome 10 open reading frame 120 2 0 1 1 1 1 1 1 916 GOLGA6L6 golgin A6 family-like 6 4 0 1 1 1 1 1 1 1093 ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 2 0 1 1 1 1 1 1 1901 RILPL1 Rab interacting lysosomal protein-like 1 2 0 1 1 1 1 1 1 2332 TRRAP transformation/transcription domain-associated protein 4 0 1 1 1 1 1 1 2574 ZNF98 zinc finger protein 98 (F7175) 2 0 1 1 1 1 1 1 1047 HTR3E 5-hydroxytryptamine (serotonin) receptor 3, family member E 2 1 0 1 1 0 1 1 2369 UBR4 ubiquitin protein ligase E3 component n-recognin 4 2 1 0 1 1 0 1 1 281 C22orf32 chromosome 22 open reading frame 32 2 4 0 0 1 0 0 1 2490 ZFHX4 zinc finger homeobox 4 3 4 0 0 1 0 0 1 801 FGB fibrinogen beta chain 2 5 0 0 1 0 0 1 1385 MUC2 mucin 2, oligomeric mucus/gel-forming 6 7 0 0 2 0 0 2 800 FGA fibrinogen alpha chain 2 8 0 0 1 0 0 1 1558 OR4D2 olfactory receptor, family 4, subfamily D, member 2 2 9 0 0 1 0 0 1 1247 LOXL2 lysyl oxidase-like 2 2 12 0 0 1 0 0 1 679 EHMT2 euchromatic histone-lysine N-methyltransferase 2 2 13 0 0 0 0 0 0 1117 KCNK10 potassium channel, subfamily K, member 10 3 13 0 0 0 0 0 0 1425 NACAD NAC alpha domain containing 2 13 0 0 0 0 0 0 1599 OXER1 oxoeicosanoid (OXE) receptor 1 2 13 0 0 0 0 0 0 2249 TIAM1 T-cell lymphoma invasion and metastasis 1 2 14 0 0 0 0 0 0 521 CTNNA2 catenin (cadherin-associated protein), alpha 2 2 15 0 0 0 0 0 0 2285 TMEM205 transmembrane protein 205 2 15 0 0 0 0 0 0 861 GALNT6 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6) 2 16 0 0 0 0 0 0 695 ENO1 enolase 1, (alpha) 2 19 0 0 0 0 0 0 878 GDF5 growth differentiation factor 5 2 19 0 0 0 0 0 0 650 DST dystonin 5 21 0 0 0 0 0 0 463 COL16A1 collagen, type XVI, alpha 1 2 23 0 0 0 0 0 0 875 GCOM1 myocardial zonula adherens protein 2 23 0 0 0 0 0 0 356 CCDC74A coiled-coil domain containing 74A 3 25 0 0 0 0 0 0 1393 MYBPHL myosin binding protein H-like 2 29 0 0 0 0 0 0 134 ARHGEF18 rho/rac guanine nucleotide exchange factor (GEF) 18 3 32 0 0 0 0 0 0 949 GRM3 glutamate receptor, metabotropic 3 2 32 0 0 0 0 0 0 1797 PTEN phosphatase and tensin homolog (mutated in multiple advanced cancers 1) 6 32 0 0 0 0 0 0 922 GPBP1 GC-rich promoter binding protein 1 2 36 0 0 0 0 0 0 328 CASC5 cancer susceptibility candidate 5 3 37 0 0 0 0 0 0 1147 KIAA1429 KIAA1429 2 37 0 0 0 0 0 0 1360 MPHOSPH8 M-phase phosphoprotein 8 2 38 0 0 0 0 0 0 167 ATP10B ATPase, class V, type 10B 2 41 0 0 0 0 0 0 784 FAT4 FAT tumor suppressor homolog 4 (Drosophila) 3 41 0 0 0 0 0 0 2469 YLPM1 YLP motif containing 1 4 41 0 0 0 0 0 0 2203 TAL1 T-cell acute lymphocytic leukemia 1 2 45 0 0 0 0 0 0 1626 PCDH1 protocadherin 1 2 52 0 0 0 0 0 0 1507 NT5C1A 5'-nucleotidase, cytosolic IA 2 53 0 0 0 0 0 0 372 CD33 CD33 molecule 2 55 0 0 0 0 0 0 1286 MAP1LC3A microtubule-associated protein 1 light chain 3 alpha 2 58 0 0 0 0 0 0 2219 TBC1D5 TBC1 domain family, member 5 2 60 0 0 0 0 0 0 649 DSPP dentin sialophosphoprotein 5 61 0 0 0 0 0 0 2183 SYBU syntabulin (syntaxin-interacting) 2 61 0 0 0 0 0 0 380 CDC27 cell division cycle 27 homolog (S. cerevisiae) 2 62 0 0 0 0 0 0 1695 PLD4 phospholipase D family, member 4 2 62 0 0 0 0 0 0 1932 RPRD2 regulation of nuclear pre-mRNA domain containing 2 3 62 0 0 0 0 0 0 2569 ZNF831 zinc finger protein 831 2 62 0 0 0 0 0 0 54 AGBL1 ATP/GTP binding protein-like 1 2 63 0 0 0 0 0 0 1620 PASD1 PAS domain containing 1 2 66 0 0 0 0 0 0 487 CPNE7 copine VII 2 70 0 0 0 0 0 0 1543 OR13C2 olfactory receptor, family 13, subfamily C, member 2 2 71 0 0 0 0 0 0 2228 TCEB3B transcription elongation factor B polypeptide 3B (elongin A2) 2 71 0 0 0 0 0 0 1197 KYNU kynureninase (L-kynurenine hydrolase) 2 73 0 0 0 0 0 0 199 BAI1 brain-specific angiogenesis inhibitor 1 2 74 0 0 0 0 0 0 1579 OR5M9 olfactory receptor, family 5, subfamily M, member 9 2 76 0 0 0 0 0 0 2190 SYT16 synaptotagmin XVI 2 76 0 0 0 0 0 0 812 FLT4 fms-related tyrosine kinase 4 4 83 0 0 0 0 0 0 15 ABHD14A abhydrolase domain containing 14A 2 93 0 0 0 0 0 0 49 ADORA2A adenosine A2a receptor 2 94 0 0 0 0 0 0 2558 ZNF653 zinc finger protein 653 2 94 0 0 0 0 0 0 1079 ILKAP integrin-linked kinase-associated serine/threonine phosphatase 2C 2 97 0 0 0 0 0 0 161 ATG2A ATG2 autophagy related 2 homolog A (S. cerevisiae) 3 106 0 0 0 0 0 0 104 ANO9 anoctamin 9 2 109 0 0 0 0 0 0 2046 SLC12A9 solute carrier family 12 (potassium/chloride transporters), member 9 2 110 0 0 0 0 0 0 1837 RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1 2 111 0 0 0 0 0 0 132 ARHGAP33 Rho GTPase activating protein 33 2 112 0 0 0 0 0 0 1324 MED8 mediator complex subunit 8 2 113 0 0 0 0 0 0 1387 MUC5B mucin 5B, oligomeric mucus/gel-forming 8 113 0 0 0 0 0 0 514 CSMD2 CUB and Sushi multiple domains 2 2 114 0 0 0 0 0 0 1639 PCLO piccolo (presynaptic cytomatrix protein) 5 114 0 0 0 0 0 0 578 DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 2 123 0 0 0 0 0 0 1524 OBSL1 obscurin-like 1 2 123 0 0 0 0 0 0 754 FAM189B family with sequence similarity 189, member B 2 125 0 0 0 0 0 0 398 CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 2 128 0 0 0 0 0 0 728 EYA1 eyes absent homolog 1 (Drosophila) 2 128 0 0 0 0 0 0 1456 NFIA nuclear factor I/A 2 129 0 0 0 0 0 0 216 BIRC3 baculoviral IAP repeat-containing 3 2 131 0 0 0 0 0 0 1656 PER3 period homolog 3 (Drosophila) 2 135 0 0 0 0 0 0 2453 WNT2B wingless-type MMTV integration site family, member 2B 2 135 0 0 0 0 0 0 87 AMPD2 adenosine monophosphate deaminase 2 (isoform L) 2 136 0 0 0 0 0 0 702 EPB42 erythrocyte membrane protein band 4.2 2 136 0 0 0 0 0 0 63 AICDA activation-induced cytidine deaminase 2 139 0 0 0 0 0 0 790 FBXO16 F-box protein 16 2 142 0 0 0 0 0 0 306 CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 2 144 0 0 0 0 0 0 1257 LRFN5 leucine rich repeat and fibronectin type III domain containing 5 2 146 0 0 0 0 0 0 1565 OR4X1 olfactory receptor, family 4, subfamily X, member 1 2 149 0 0 0 0 0 0 2405 USP9X ubiquitin specific peptidase 9, X-linked 4 156 0 0 0 0 0 0 311 CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 2 158 0 0 0 0 0 0 1140 KIAA1211 KIAA1211 4 159 0 0 0 0 0 0 1153 KIAA1755 KIAA1755 2 159 0 0 0 0 0 0 697 ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin) 2 163 0 0 0 0 0 0 2157 SSC5D scavenger receptor cysteine rich domain containing (5 domains) 4 163 0 0 0 0 0 0 1743 PPAT phosphoribosyl pyrophosphate amidotransferase 2 164 0 0 0 0 0 0 1212 LCT lactase 2 165 0 0 0 0 0 0 1771 PRIC285 helicase with zinc finger 2, transcriptional coactivator 3 166 0 0 0 0 0 0 416 CHD4 chromodomain helicase DNA binding protein 4 2 167 0 0 0 0 0 0 711 EPT1 ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific) 2 169 0 0 0 0 0 0 854 GADL1 glutamate decarboxylase-like 1 2 174 0 0 0 0 0 0 371 CD276 CD276 molecule 2 176 0 0 0 0 0 0 1143 KIAA1324 KIAA1324 2 178 0 0 0 0 0 0 1811 PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) 2 181 0 0 0 0 0 0 1745 PPFIA2 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 2 182 0 0 0 0 0 0 1044 HSPD1 heat shock 60kDa protein 1 (chaperonin) 2 183 0 0 0 0 0 0 291 C3orf58 chromosome 3 open reading frame 58 2 185 0 0 0 0 0 0 789 FBXL5 F-box and leucine-rich repeat protein 5 2 189 0 0 0 0 0 0 1120 KCNN3 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 2 189 0 0 0 0 0 0 991 HERC2 hect domain and RLD 2 4 196 0 0 0 0 0 0 1628 PCDH12 protocadherin 12 3 200 0 0 0 0 0 0 510 CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 3 209 0 0 0 0 0 0 2259 TKTL2 transketolase-like 2 2 211 0 0 0 0 0 0 742 FAM153B family with sequence similarity 153, member B 2 214 0 0 0 0 0 0 1411 MYO7A myosin VIIA 2 215 0 0 0 0 0 0 1869 RC3H2 ring finger and CCCH-type zinc finger domains 2 2 217 0 0 0 0 0 0 2561 ZNF709 zinc finger protein 709 2 224 0 0 0 0 0 0 441 CLCN2 chloride channel 2 2 225 0 0 0 0 0 0 37 ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 2 227 0 0 0 0 0 0 1642 PCSK5 proprotein convertase subtilisin/kexin type 5 2 228 0 0 0 0 0 0 250 C14orf135 chromosome 14 open reading frame 135 2 231 0 0 0 0 0 0 977 HCN4 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 2 231 0 0 0 0 0 0 2269 TMC3 transmembrane channel-like 3 2 231 0 0 0 0 0 0 2395 USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 2 231 0 0 0 0 0 0 1436 NCL nucleolin 2 233 0 0 0 0 0 0 896 GK2 glycerol kinase 2 2 236 0 0 0 0 0 0 613 DMXL1 Dmx-like 1 3 247 0 0 0 0 0 0 1495 NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 2 250 0 0 0 0 0 0 2476 ZBTB34 zinc finger and BTB domain containing 34 2 258 0 0 0 0 0 0 2331 TRPS1 trichorhinophalangeal syndrome I 2 264 0 0 0 0 0 0 610 DMD dystrophin (muscular dystrophy, Duchenne and Becker types) 4 265 0 0 0 0 0 0 57 AGPAT9 1-acylglycerol-3-phosphate O-acyltransferase 9 2 272 0 0 0 0 0 0 669 EEF1A2 eukaryotic translation elongation factor 1 alpha 2 2 273 0 0 0 0 0 0 615 DNAH1 dynein, axonemal, heavy chain 1 3 274 0 0 0 0 0 0 603 DIDO1 death inducer-obliterator 1 2 282 0 0 0 0 0 0 685 EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 2 295 0 0 0 0 0 0 2472 ZAN zonadhesin 5 295 0 0 0 0 0 0 2066 SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 2 296 0 0 0 0 0 0 1061 IGSF10 immunoglobulin superfamily, member 10 3 298 0 0 0 0 0 0 1805 PTPRD protein tyrosine phosphatase, receptor type, D 2 303 0 0 0 0 0 0 173 ATP13A3 ATPase type 13A3 2 307 0 0 0 0 0 0 1154 KIAA2018 KIAA2018 3 310 0 0 0 0 0 0 2378 UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7 2 322 0 0 0 0 0 0 1242 LMTK3 lemur tyrosine kinase 3 2 331 0 0 0 0 0 0 2035 SIPA1 signal-induced proliferation-associated gene 1 2 338 0 0 0 0 0 0 1936 RREB1 ras responsive element binding protein 1 2 342 0 0 0 0 0 0 305 CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 3 344 0 0 0 0 0 0 2158 SSPO SCO-spondin homolog (Bos taurus) 2 348 0 0 0 0 0 0 1338 MICAL1 microtubule associated monoxygenase, calponin and LIM domain containing 1 2 366 0 0 0 0 0 0 1784 PRODH proline dehydrogenase (oxidase) 1 2 371 0 0 0 0 0 0 911 GNS glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID) 2 388 0 0 0 0 0 0 164 ATM ataxia telangiectasia mutated 3 392 0 0 0 0 0 0 1806 PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 2 402 0 0 0 0 0 0 136 ARHGEF2 rho/rac guanine nucleotide exchange factor (GEF) 2 2 403 0 0 0 0 0 0 1380 MTOR mechanistic target of rapamycin (serine/threonine kinase) 2 410 0 0 0 0 0 0 2149 SRCRB4D scavenger receptor cysteine rich domain containing, group B (4 domains) 2 410 0 0 0 0 0 0 2351 TTN titin 4 414 0 0 0 0 0 0 1443 NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) 2 427 0 0 0 0 0 0 1138 KIAA0947 KIAA0947 3 428 0 0 0 0 0 0 1455 NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 2 430 0 0 0 0 0 0 1384 MUC16 mucin 16, cell surface associated 8 436 0 0 0 0 0 0 719 ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 2 438 0 0 0 0 0 0 2101 SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 2 442 0 0 0 0 0 0 2386 UNC80 unc-80 homolog (C. elegans) 3 447 0 0 0 0 0 0 2521 ZNF318 zinc finger protein 318 2 447 0 0 0 0 0 0 185 ATP9B ATPase, class II, type 9B 2 450 0 0 0 0 0 0 2543 ZNF528 zinc finger protein 528 2 451 0 0 0 0 0 0 2105 SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 2 456 0 0 0 0 0 0 1730 POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 2 463 0 0 0 0 0 0 1594 OTOA otoancorin 2 472 0 0 0 0 0 0 1680 PKD1L2 polycystic kidney disease 1-like 2 2 478 0 0 0 0 0 0 1409 MYO1F myosin IF 2 481 0 0 0 0 0 0 97 ANKRD27 ankyrin repeat domain 27 (VPS9 domain) 2 495 0 0 0 0 0 0 449 CLTCL1 clathrin, heavy chain-like 1 2 502 0 0 0 0 0 0 657 DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 3 505 0 0 0 0 0 0 1316 MCTP1 multiple C2 domains, transmembrane 1 2 505 0 0 0 0 0 0 1388 MUC6 mucin 6, oligomeric mucus/gel-forming 3 511 0 0 0 0 0 0 1929 RPH3A rabphilin 3A homolog (mouse) 2 531 0 0 0 0 0 0 2178 STXBP5 syntaxin binding protein 5 (tomosyn) 2 552 0 0 0 0 0 0 643 DSCAM Down syndrome cell adhesion molecule 2 554 0 0 0 0 0 0 1406 MYO15A myosin XVA 3 559 0 0 0 0 0 0 2536 ZNF469 zinc finger protein 469 3 564 0 0 0 0 0 0 52 AFF3 AF4/FMR2 family, member 3 2 570 0 0 0 0 0 0 2337 TSHZ3 teashirt zinc finger homeobox 3 2 573 0 0 0 0 0 0 2334 TSC2 tuberous sclerosis 2 2 574 0 0 0 0 0 0 1250 LPHN1 latrophilin 1 2 579 0 0 0 0 0 0 1096 ITGA9 integrin, alpha 9 2 598 0 0 0 0 0 0 2003 SEZ6L seizure related 6 homolog (mouse)-like 2 602 0 0 0 0 0 0 2245 THADA thyroid adenoma associated 2 607 0 0 0 0 0 0 1608 PACS1 phosphofurin acidic cluster sorting protein 1 2 617 0 0 0 0 0 0 217 BIRC6 baculoviral IAP repeat-containing 6 (apollon) 2 640 0 0 0 0 0 0 1390 MUSK muscle, skeletal, receptor tyrosine kinase 2 656 0 0 0 0 0 0 1252 LPIN1 lipin 1 2 660 0 0 0 0 0 0 1440 NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 2 682 0 0 0 0 0 0 2124 SPAG5 sperm associated antigen 5 2 695 0 0 0 0 0 0 614 DMXL2 Dmx-like 2 2 707 0 0 0 0 0 0 1429 NBEAL1 neurobeachin-like 1 2 746 0 0 0 0 0 0 1920 ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 2 746 0 0 0 0 0 0 2260 TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 2 751 0 0 0 0 0 0 1312 MCM2 minichromosome maintenance complex component 2 2 776 0 0 0 0 0 0 233 BSN bassoon (presynaptic cytomatrix protein) 3 782 0 0 0 0 0 0 1136 KIAA0430 KIAA0430 2 794 0 0 0 0 0 0 618 DNAH3 dynein, axonemal, heavy chain 3 2 796 0 0 0 0 0 0 2123 SPAG17 sperm associated antigen 17 2 796 0 0 0 0 0 0 1465 NIPBL Nipped-B homolog (Drosophila) 2 808 0 0 0 0 0 0 2077 SLC4A5 solute carrier family 4, sodium bicarbonate cotransporter, member 5 2 834 0 0 0 0 0 0 752 FAM184A family with sequence similarity 184, member A 3 839 0 0 0 0 0 0 1241 LMTK2 lemur tyrosine kinase 2 2 855 0 0 0 0 0 0 1693 PLCE1 phospholipase C, epsilon 1 2 902 0 0 0 0 0 0 461 COL12A1 collagen, type XII, alpha 1 2 919 0 0 0 0 0 0 975 HCFC1 host cell factor C1 (VP16-accessory protein) 2 984 0 0 0 0 0 0 2443 WDR7 WD repeat domain 7 2 989 0 0 0 0 0 0 2242 TG thyroglobulin 3 1000 0 0 0 0 0 0 224 BPTF bromodomain PHD finger transcription factor 2 1005 0 0 0 0 0 0 1124 KCNT1 potassium channel, subfamily T, member 1 2 1007 0 0 0 0 0 0 399 CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila) 2 1016 0 0 0 0 0 0 2000 SETD2 SET domain containing 2 2 1037 0 0 0 0 0 0 1048 HUWE1 HECT, UBA and WWE domain containing 1 2 1056 0 0 0 0 0 0 2187 SYNE1 spectrin repeat containing, nuclear envelope 1 2 1074 0 0 0 0 0 0 1948 RYR1 ryanodine receptor 1 (skeletal) 2 1111 0 0 0 0 0 0 626 DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13 2 1213 0 0 0 0 0 0 1105 KALRN kalirin, RhoGEF kinase 2 1376 0 0 0 0 0 0 783 FAT3 FAT tumor suppressor homolog 3 (Drosophila) 2 1408 0 0 0 0 0 0 1336 MGA MAX gene associated 2 1430 0 0 0 0 0 0 1683 PKDREJ polycystic kidney disease (polycystin) and REJ homolog (sperm receptor for egg jelly homolog, sea urchin) 2 1431 0 0 0 0 0 0 61 AHNAK2 AHNAK nucleoprotein 2 2 1432 0 0 0 0 0 0 2393 USH2A Usher syndrome 2A (autosomal recessive, mild) 2 1507 0 0 0 0 0 0 1045 HSPG2 heparan sulfate proteoglycan 2 2 1800 0 0 0 0 0 0 415 CHD3 chromodomain helicase DNA binding protein 3 2 1859 0 0 0 0 0 0 513 CSMD1 CUB and Sushi multiple domains 1 2 2050 0 0 0 0 0 0 92 ANKHD1-EIF4EBP3 ANKHD1-EIF4EBP3 2 2481 0 0 0 0 0 0 2434 WDFY3 WD repeat and FYVE domain containing 3 2 2579 0 0 0 0 0 0 1345 MLL3 myeloid/lymphoid or mixed-lineage leukemia 3 2 2668 0 0 0 0 0 0 1139 KIAA1109 KIAA1109 2 2902 0 0 0 0 0 0