Clinical Features Time to Death AGE NEOPLASM.DISEASESTAGE PATHOLOGY.T.STAGE PATHOLOGY.N.STAGE PATHOLOGY.M.STAGE GENDER KARNOFSKY.PERFORMANCE.SCORE NUMBERPACKYEARSSMOKED YEAROFTOBACCOSMOKINGONSET nCNV (%) nWild-Type logrank test_P logrank test_Q t-test_P t-test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q t-test_P t-test_Q t-test_P t-test_Q t-test_P t-test_Q 1Q GAIN MUTATION ANALYSIS 11 (9%) 118 1.276e-05 0.00586 0.38587 1 0.00027201 0.123 9.1109e-05 0.0415 0.37907 1 0.15611 1 0.094443 1 NA NA NA NA NA NA 2P GAIN MUTATION ANALYSIS 21 (16%) 108 0.092037 1 0.22019 1 0.054903 1 0.58607 1 0.20256 1 0.0014143 0.629 0.44911 1 0.54095 1 NA NA NA NA 2Q GAIN MUTATION ANALYSIS 23 (18%) 106 0.17743 1 0.61977 1 0.01383 1 0.57103 1 0.1273 1 0.0026294 1 0.45583 1 0.50088 1 NA NA NA NA 3P GAIN MUTATION ANALYSIS 36 (28%) 93 0.2386 1 0.79218 1 0.092567 1 0.032211 1 1 1 0.25419 1 0.40287 1 0.12978 1 NA NA NA NA 3Q GAIN MUTATION ANALYSIS 41 (32%) 88 0.10529 1 0.6748 1 0.12895 1 0.080428 1 1 1 0.14338 1 0.15503 1 0.24817 1 NA NA NA NA 4P GAIN MUTATION ANALYSIS 6 (5%) 123 0.022551 1 0.0042536 1 0.091959 1 0.85011 1 0.52962 1 0.19344 1 0.66519 1 NA NA NA NA NA NA 4Q GAIN MUTATION ANALYSIS 5 (4%) 124 0.35959 1 0.014079 1 0.38741 1 0.66244 1 0.28432 1 0.68991 1 1 1 NA NA NA NA NA NA 5P GAIN MUTATION ANALYSIS 20 (16%) 109 0.44867 1 0.32342 1 0.2328 1 0.21715 1 0.86231 1 0.29141 1 0.60801 1 0.39661 1 NA NA NA NA 5Q GAIN MUTATION ANALYSIS 19 (15%) 110 0.1487 1 0.6311 1 0.30528 1 0.30221 1 1 1 0.30259 1 0.7904 1 0.39661 1 NA NA NA NA 6P GAIN MUTATION ANALYSIS 4 (3%) 125 0.063906 1 0.35644 1 0.062369 1 0.15707 1 0.4338 1 0.006108 1 0.30995 1 NA NA NA NA NA NA 6Q GAIN MUTATION ANALYSIS 3 (2%) 126 8.5329e-06 0.00393 0.25697 1 0.047659 1 0.51313 1 NA NA 0.0061601 1 0.55182 1 NA NA NA NA NA NA 7P GAIN MUTATION ANALYSIS 71 (55%) 58 0.10988 1 0.80904 1 0.0027026 1 0.0132 1 0.80477 1 0.15973 1 0.059296 1 0.18391 1 NA NA NA NA 7Q GAIN MUTATION ANALYSIS 73 (57%) 56 0.099094 1 0.71604 1 0.0038651 1 0.018618 1 0.72644 1 0.27553 1 0.08628 1 0.18391 1 NA NA NA NA 8P GAIN MUTATION ANALYSIS 10 (8%) 119 0.046577 1 0.89379 1 0.48669 1 0.35761 1 0.44067 1 0.84895 1 0.49915 1 NA NA NA NA NA NA 8Q GAIN MUTATION ANALYSIS 13 (10%) 116 3.614e-05 0.0166 0.83792 1 0.057616 1 0.044205 1 0.030472 1 0.38106 1 0.2215 1 NA NA NA NA NA NA 10P GAIN MUTATION ANALYSIS 5 (4%) 124 0.54043 1 0.93248 1 0.25545 1 0.51547 1 NA NA 0.50992 1 1 1 NA NA NA NA NA NA 10Q GAIN MUTATION ANALYSIS 4 (3%) 125 0.50053 1 0.81139 1 0.27065 1 0.58857 1 NA NA 0.68991 1 1 1 NA NA NA NA NA NA 11P GAIN MUTATION ANALYSIS 6 (5%) 123 0.035704 1 0.30293 1 0.055786 1 0.050849 1 0.72125 1 0.012041 1 1 1 NA NA NA NA NA NA 11Q GAIN MUTATION ANALYSIS 4 (3%) 125 0.75472 1 0.12737 1 0.27065 1 0.09564 1 1 1 0.14377 1 0.58739 1 NA NA NA NA NA NA 12P GAIN MUTATION ANALYSIS 49 (38%) 80 0.34756 1 0.77605 1 0.58207 1 0.46318 1 0.49255 1 0.10852 1 0.1188 1 0.24817 1 NA NA NA NA 12Q GAIN MUTATION ANALYSIS 49 (38%) 80 0.34756 1 0.77605 1 0.58207 1 0.46318 1 0.49255 1 0.10852 1 0.1188 1 0.24817 1 NA NA NA NA 13Q GAIN MUTATION ANALYSIS 15 (12%) 114 0.48487 1 0.15543 1 0.48112 1 0.52733 1 NA NA 1 1 1 1 0.19723 1 NA NA NA NA 16P GAIN MUTATION ANALYSIS 66 (51%) 63 0.98448 1 0.44953 1 0.59918 1 0.96728 1 1 1 0.26341 1 0.0072824 1 0.52928 1 NA NA NA NA 16Q GAIN MUTATION ANALYSIS 64 (50%) 65 0.30379 1 0.66327 1 0.59923 1 0.90672 1 0.8042 1 0.037346 1 0.035901 1 0.25009 1 NA NA NA NA 17P GAIN MUTATION ANALYSIS 71 (55%) 58 0.11442 1 0.020901 1 0.0021299 0.946 0.0051037 1 0.22666 1 0.00016719 0.0757 0.023469 1 0.18216 1 NA NA NA NA 17Q GAIN MUTATION ANALYSIS 84 (65%) 45 0.71754 1 0.063728 1 0.44922 1 0.3767 1 0.50638 1 0.0026541 1 0.11493 1 0.56139 1 NA NA NA NA 18P GAIN MUTATION ANALYSIS 7 (5%) 122 0.84986 1 0.5857 1 0.48493 1 0.53831 1 NA NA 0.13634 1 1 1 0.54095 1 NA NA NA NA 18Q GAIN MUTATION ANALYSIS 5 (4%) 124 0.36296 1 0.95442 1 0.73321 1 0.66244 1 NA NA 0.68991 1 1 1 NA NA NA NA NA NA 20P GAIN MUTATION ANALYSIS 42 (33%) 87 0.81466 1 0.018917 1 0.60562 1 0.52996 1 0.87567 1 0.49243 1 0.83926 1 0.63637 1 NA NA NA NA 20Q GAIN MUTATION ANALYSIS 45 (35%) 84 0.48259 1 0.014432 1 0.3976 1 0.43182 1 0.77103 1 0.89848 1 1 1 0.63637 1 NA NA NA NA 21Q GAIN MUTATION ANALYSIS 6 (5%) 123 0.75472 1 0.027642 1 0.56108 1 0.2514 1 NA NA 0.50992 1 0.66519 1 NA NA NA NA NA NA XQ GAIN MUTATION ANALYSIS 38 (29%) 91 0.67264 1 0.60882 1 0.16014 1 0.14585 1 1 1 0.5685 1 0.14501 1 0.13601 1 NA NA NA NA 1P LOSS MUTATION ANALYSIS 17 (13%) 112 0.69955 1 0.64495 1 0.44557 1 0.56548 1 0.33981 1 0.91205 1 0.77948 1 0.34189 1 NA NA NA NA 1Q LOSS MUTATION ANALYSIS 10 (8%) 119 0.56259 1 0.39813 1 0.25468 1 0.64503 1 NA NA 0.48057 1 1 1 0.34189 1 NA NA NA NA 3P LOSS MUTATION ANALYSIS 9 (7%) 120 0.17759 1 0.11123 1 0.0071826 1 0.0059858 1 0.72413 1 0.088473 1 0.71983 1 NA NA NA NA NA NA 3Q LOSS MUTATION ANALYSIS 3 (2%) 126 2.3712e-06 0.00109 0.32314 1 0.094259 1 0.066549 1 0.4338 1 0.14377 1 1 1 NA NA NA NA NA NA 4P LOSS MUTATION ANALYSIS 11 (9%) 118 0.1932 1 0.053075 1 0.0099591 1 0.0041426 1 0.027946 1 0.4676 1 0.0037147 1 NA NA NA NA NA NA 4Q LOSS MUTATION ANALYSIS 12 (9%) 117 0.81652 1 0.23725 1 0.038683 1 0.037736 1 0.26662 1 0.11955 1 0.047156 1 NA NA NA NA NA NA 5P LOSS MUTATION ANALYSIS 6 (5%) 123 0.00012432 0.0564 0.11384 1 0.055786 1 0.026212 1 0.017189 1 0.19344 1 0.073887 1 NA NA NA NA NA NA 5Q LOSS MUTATION ANALYSIS 5 (4%) 124 0.020053 1 0.11441 1 0.25545 1 0.04661 1 0.039373 1 0.28385 1 0.17251 1 NA NA NA NA NA NA 6P LOSS MUTATION ANALYSIS 10 (8%) 119 0.094118 1 0.50145 1 0.14749 1 0.10097 1 0.52962 1 1 1 0.28319 1 0.24817 1 NA NA NA NA 6Q LOSS MUTATION ANALYSIS 12 (9%) 117 0.341 1 0.82045 1 0.11879 1 0.025339 1 0.58738 1 0.43096 1 0.047156 1 0.38346 1 NA NA NA NA 8P LOSS MUTATION ANALYSIS 5 (4%) 124 0.00083392 0.374 0.20907 1 0.040995 1 0.51547 1 NA NA 0.019611 1 0.17251 1 NA NA NA NA NA NA 8Q LOSS MUTATION ANALYSIS 3 (2%) 126 0.014503 1 0.60092 1 0.11946 1 0.35624 1 NA NA 0.14377 1 0.22689 1 NA NA NA NA NA NA 9P LOSS MUTATION ANALYSIS 17 (13%) 112 0.072136 1 0.53512 1 0.0031715 1 0.0035346 1 0.37371 1 0.049464 1 0.011585 1 0.39765 1 NA NA NA NA 9Q LOSS MUTATION ANALYSIS 18 (14%) 111 0.095429 1 0.86753 1 0.024877 1 0.0023962 1 0.20256 1 0.25912 1 0.096303 1 0.39765 1 NA NA NA NA 10P LOSS MUTATION ANALYSIS 8 (6%) 121 0.87819 1 0.73557 1 0.14 1 0.079501 1 0.10244 1 0.13634 1 0.70263 1 0.39661 1 NA NA NA NA 10Q LOSS MUTATION ANALYSIS 8 (6%) 121 0.2194 1 0.47323 1 0.072318 1 0.023717 1 0.33981 1 0.30039 1 1 1 0.39661 1 NA NA NA NA 11P LOSS MUTATION ANALYSIS 9 (7%) 120 0.013042 1 0.056846 1 0.18457 1 0.23073 1 0.4338 1 0.48057 1 0.45757 1 NA NA NA NA NA NA 11Q LOSS MUTATION ANALYSIS 12 (9%) 117 0.0010923 0.488 0.028838 1 0.0042373 1 0.0021519 0.953 0.28475 1 0.15611 1 1 1 NA NA NA NA NA NA 13Q LOSS MUTATION ANALYSIS 11 (9%) 118 0.023728 1 0.27323 1 0.071915 1 0.042734 1 0.08233 1 0.4676 1 0.0037147 1 NA NA NA NA NA NA 14Q LOSS MUTATION ANALYSIS 27 (21%) 102 0.59636 1 0.72983 1 0.081718 1 0.11669 1 0.27368 1 0.21332 1 0.24614 1 0.37708 1 NA NA NA NA 15Q LOSS MUTATION ANALYSIS 14 (11%) 115 0.004946 1 0.17818 1 0.29841 1 0.076056 1 0.26662 1 0.057755 1 0.76177 1 0.65354 1 NA NA NA NA 16P LOSS MUTATION ANALYSIS 4 (3%) 125 4.2772e-05 0.0195 0.65268 1 0.25545 1 0.15707 1 NA NA 1 1 0.088171 1 NA NA NA NA NA NA 16Q LOSS MUTATION ANALYSIS 4 (3%) 125 4.2772e-05 0.0195 0.65268 1 0.25545 1 0.15707 1 NA NA 1 1 0.088171 1 NA NA NA NA NA NA 17P LOSS MUTATION ANALYSIS 7 (5%) 122 4.0613e-09 1.88e-06 0.86347 1 0.0066848 1 0.033157 1 0.10814 1 0.055531 1 0.20216 1 NA NA NA NA NA NA 18P LOSS MUTATION ANALYSIS 20 (16%) 109 0.058908 1 0.42723 1 0.010733 1 0.0026688 1 0.20256 1 0.05746 1 1 1 0.34189 1 NA NA NA NA 18Q LOSS MUTATION ANALYSIS 21 (16%) 108 0.058908 1 0.42723 1 0.0048689 1 0.0009709 0.435 0.20256 1 0.041995 1 0.80071 1 0.34189 1 NA NA NA NA 19P LOSS MUTATION ANALYSIS 9 (7%) 120 0.64686 1 0.46996 1 0.1181 1 0.052401 1 1 1 0.30039 1 1 1 NA NA NA NA NA NA 19Q LOSS MUTATION ANALYSIS 8 (6%) 121 0.74102 1 0.74728 1 0.047435 1 0.017935 1 1 1 0.13634 1 0.70263 1 NA NA NA NA NA NA 21Q LOSS MUTATION ANALYSIS 23 (18%) 106 0.42534 1 0.47241 1 0.011243 1 0.0097139 1 0.32955 1 0.11984 1 0.45583 1 NA NA NA NA NA NA 22Q LOSS MUTATION ANALYSIS 31 (24%) 98 0.78811 1 0.60172 1 0.0007331 0.33 0.00062638 0.282 0.14012 1 0.11816 1 0.073545 1 0.44484 1 NA NA NA NA XQ LOSS MUTATION ANALYSIS 19 (15%) 110 0.0012652 0.564 0.087298 1 0.062102 1 0.016031 1 0.039195 1 0.31714 1 0.288 1 0.45826 1 NA NA NA NA