Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.514 0.374 0.773 92.0 -9999.0 0.0 92.0 KIRREL -0.088 0.188 -9999.0 0.0 -0.963 6.0 6.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.515 0.376 -9999.0 0.0 -0.776 92.0 92.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.602 0.421 -9999.0 0.0 -0.801 106.0 106.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.442 0.334 -9999.0 0.0 -0.597 106.0 106.0 FYN -0.565 0.404 -9999.0 0.0 -0.757 106.0 106.0 mol:Ca2+ -0.591 0.411 -9999.0 0.0 -0.786 106.0 106.0 mol:DAG -0.597 0.416 -9999.0 0.0 -0.794 106.0 106.0 NPHS2 -0.459 0.447 -9999.0 0.0 -0.934 66.0 66.0 mol:IP3 -0.597 0.416 -9999.0 0.0 -0.794 106.0 106.0 regulation of endocytosis -0.534 0.374 -9999.0 0.0 -0.71 106.0 106.0 Nephrin/NEPH1/podocin/Cholesterol -0.608 0.424 -9999.0 0.0 -0.809 106.0 106.0 establishment of cell polarity -0.514 0.374 -9999.0 0.0 -0.773 92.0 92.0 Nephrin/NEPH1/podocin/NCK1-2 -0.563 0.398 -9999.0 0.0 -0.748 106.0 106.0 Nephrin/NEPH1/beta Arrestin2 -0.547 0.387 -9999.0 0.0 -0.727 106.0 106.0 NPHS1 -0.606 0.431 -9999.0 0.0 -0.919 92.0 92.0 Nephrin/NEPH1/podocin -0.576 0.404 -9999.0 0.0 -0.766 106.0 106.0 TJP1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.602 0.421 -9999.0 0.0 -0.801 106.0 106.0 CD2AP 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.602 0.421 -9999.0 0.0 -0.801 106.0 106.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.666 0.449 -9999.0 0.0 -0.843 112.0 112.0 cytoskeleton organization -0.588 0.432 -9999.0 0.0 -0.793 106.0 106.0 Nephrin/NEPH1 -0.398 0.298 -9999.0 0.0 -0.602 92.0 92.0 Nephrin/NEPH1/ZO-1 -0.431 0.322 -9999.0 0.0 -0.652 92.0 92.0