Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.381 0.295 0.582 92.0 -9999.0 0.0 92.0 KIRREL -0.084 0.151 -9999.0 0.0 -0.759 6.0 6.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.382 0.296 -9999.0 0.0 -0.583 92.0 92.0 PLCG1 0.025 0.007 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.025 0.008 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.022 0.011 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.423 0.334 -9999.0 0.0 -0.6 102.0 102.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.348 0.276 -9999.0 0.0 -0.51 94.0 94.0 FYN -0.414 0.297 0.265 1.0 -0.567 102.0 103.0 mol:Ca2+ -0.414 0.328 -9999.0 0.0 -0.598 99.0 99.0 mol:DAG -0.417 0.33 -9999.0 0.0 -0.601 99.0 99.0 NPHS2 -0.358 0.344 -9999.0 0.0 -0.733 64.0 64.0 mol:IP3 -0.417 0.33 -9999.0 0.0 -0.601 99.0 99.0 regulation of endocytosis -0.377 0.297 -9999.0 0.0 -0.54 100.0 100.0 Nephrin/NEPH1/podocin/Cholesterol -0.428 0.327 -9999.0 0.0 -0.6 102.0 102.0 establishment of cell polarity -0.381 0.295 -9999.0 0.0 -0.582 92.0 92.0 Nephrin/NEPH1/podocin/NCK1-2 -0.394 0.321 -9999.0 0.0 -0.567 101.0 101.0 Nephrin/NEPH1/beta Arrestin2 -0.384 0.303 -9999.0 0.0 -0.549 100.0 100.0 NPHS1 -0.476 0.33 -9999.0 0.0 -0.714 92.0 92.0 Nephrin/NEPH1/podocin -0.407 0.314 -9999.0 0.0 -0.572 102.0 102.0 TJP1 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.026 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.419 0.333 -9999.0 0.0 -0.605 99.0 99.0 CD2AP 0.025 0.007 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.419 0.333 -9999.0 0.0 -0.605 99.0 99.0 GRB2 0.025 0.008 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.483 0.33 0.275 1.0 -0.628 108.0 109.0 cytoskeleton organization -0.438 0.333 -9999.0 0.0 -0.645 92.0 92.0 Nephrin/NEPH1 -0.282 0.227 -9999.0 0.0 -0.437 91.0 91.0 Nephrin/NEPH1/ZO-1 -0.313 0.257 -9999.0 0.0 -0.498 88.0 88.0