Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.015 0.192 0.346 1.0 -0.455 16.0 17.0 MAP3K8 0.021 0.015 -9999.0 0.0 -9999.0 0.0 0.0 FOS 0.002 0.143 0.301 3.0 -0.46 7.0 10.0 PRKCA 0.018 0.019 -9999.0 0.0 -9999.0 0.0 0.0 PTPN7 0.013 0.064 -9999.0 0.0 -0.691 1.0 1.0 HRAS 0.026 0.007 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB 0.017 0.021 -9999.0 0.0 -9999.0 0.0 0.0 NRAS 0.025 0.009 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.039 0.029 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 0.012 0.1 -9999.0 0.0 -0.466 5.0 5.0 MAP2K1 0.024 0.048 -9999.0 0.0 -9999.0 0.0 0.0 ELK1 0.017 0.025 -9999.0 0.0 -9999.0 0.0 0.0 BRAF 0.011 0.018 -9999.0 0.0 -9999.0 0.0 0.0 mol:GTP -0.001 0.003 -9999.0 0.0 -0.007 24.0 24.0 MAPK1 -0.012 0.145 -9999.0 0.0 -0.434 13.0 13.0 RAF1 0.012 0.02 -9999.0 0.0 -9999.0 0.0 0.0 KRAS 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0