Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.021 0.105 0.246 29.0 -9999.0 0.0 29.0 KIRREL -0.052 0.138 -9999.0 0.0 -0.343 30.0 30.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.021 0.105 -9999.0 0.0 -0.246 29.0 29.0 PLCG1 0.019 0.063 -9999.0 0.0 -0.337 5.0 5.0 ARRB2 0.029 0.01 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.028 0.012 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.009 0.093 -9999.0 0.0 -0.187 29.0 29.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.018 0.081 -9999.0 0.0 -0.19 29.0 29.0 FYN -0.024 0.086 0.235 6.0 -0.174 29.0 35.0 mol:Ca2+ -0.0 0.097 -9999.0 0.0 -0.189 33.0 33.0 mol:DAG 0.0 0.098 -9999.0 0.0 -0.189 33.0 33.0 NPHS2 -0.001 0.028 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 0.0 0.098 -9999.0 0.0 -0.189 33.0 33.0 regulation of endocytosis 0.004 0.084 -9999.0 0.0 -0.164 31.0 31.0 Nephrin/NEPH1/podocin/Cholesterol -0.005 0.081 -9999.0 0.0 -0.178 29.0 29.0 establishment of cell polarity -0.021 0.105 -9999.0 0.0 -0.246 29.0 29.0 Nephrin/NEPH1/podocin/NCK1-2 0.025 0.091 -9999.0 0.0 -0.167 29.0 29.0 Nephrin/NEPH1/beta Arrestin2 0.005 0.085 -9999.0 0.0 -0.165 31.0 31.0 NPHS1 0.0 0.029 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin -0.004 0.084 0.175 1.0 -0.171 32.0 33.0 TJP1 -0.002 0.094 -9999.0 0.0 -0.337 12.0 12.0 NCK1 0.031 0.006 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.032 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.002 0.099 -9999.0 0.0 -0.19 33.0 33.0 CD2AP 0.03 0.029 -9999.0 0.0 -0.337 1.0 1.0 Nephrin/NEPH1/podocin/GRB2 0.009 0.09 -9999.0 0.0 -0.181 29.0 29.0 GRB2 0.03 0.008 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.032 0.066 0.155 3.0 -0.165 28.0 31.0 cytoskeleton organization -0.03 0.084 0.203 2.0 -0.203 29.0 31.0 Nephrin/NEPH1 -0.01 0.072 -9999.0 0.0 -0.164 29.0 29.0 Nephrin/NEPH1/ZO-1 -0.02 0.103 -9999.0 0.0 -0.199 40.0 40.0