Clinical Features	Time to Death		AGE		GENDER		KARNOFSKY.PERFORMANCE.SCORE		HISTOLOGICAL.TYPE		RADIATIONS.RADIATION.REGIMENINDICATION	
	nCNV (%)	nWild-Type	logrank test_P	logrank test_Q	t-test_P	t-test_Q	Fisher's exact test_P	Fisher's exact test_Q	t-test_P	t-test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
1P GAIN MUTATION ANALYSIS	8 (3%)	221	0.0014475	0.58	0.089667	1	0.14354	1	0.07631	1	0.0026729	1	1	1
1Q GAIN MUTATION ANALYSIS	12 (5%)	217	0.82778	1	0.0036328	1	0.14048	1	0.4398	1	0.13416	1	1	1
2P GAIN MUTATION ANALYSIS	5 (2%)	224	0.86479	1	0.25867	1	0.65808	1	0.35312	1	0.522	1	1	1
2Q GAIN MUTATION ANALYSIS	5 (2%)	224	0.86479	1	0.25867	1	0.65808	1	0.35312	1	0.522	1	1	1
3P GAIN MUTATION ANALYSIS	7 (3%)	222	0.010922	1	0.09012	1	0.24652	1	0.70407	1	0.15926	1	1	1
3Q GAIN MUTATION ANALYSIS	7 (3%)	222	0.00024456	0.0998	0.085729	1	0.70293	1	0.27311	1	0.070763	1	0.43753	1
6P GAIN MUTATION ANALYSIS	4 (2%)	225	0.75068	1	0.34134	1	1	1	0.076311	1	0.48698	1	0.64681	1
6Q GAIN MUTATION ANALYSIS	3 (1%)	226	0.71225	1	0.66556	1	0.58686	1	0.076311	1	0.48698	1	0.56302	1
7P GAIN MUTATION ANALYSIS	54 (24%)	175	0.0068288	1	0.001929	0.772	0.084403	1	0.87649	1	0.16986	1	0.87367	1
7Q GAIN MUTATION ANALYSIS	68 (30%)	161	0.003495	1	8.5332e-05	0.035	0.19162	1	0.60548	1	0.18823	1	0.76761	1
8P GAIN MUTATION ANALYSIS	22 (10%)	207	0.60912	1	0.44681	1	0.26146	1	0.97813	1	0.13752	1	0.82243	1
8Q GAIN MUTATION ANALYSIS	27 (12%)	202	0.88374	1	0.10574	1	0.2251	1	0.5541	1	0.027816	1	0.83729	1
9P GAIN MUTATION ANALYSIS	8 (3%)	221	0.020975	1	0.10156	1	0.14354	1	0.49951	1	0.54666	1	1	1
9Q GAIN MUTATION ANALYSIS	9 (4%)	220	0.0069317	1	0.070844	1	0.011759	1	0.78819	1	0.4786	1	1	1
10P GAIN MUTATION ANALYSIS	25 (11%)	204	0.64539	1	0.034533	1	0.090397	1	0.059373	1	0.064065	1	0.003933	1
10Q GAIN MUTATION ANALYSIS	3 (1%)	226	0.41389	1	0.11332	1	0.25569	1	NA	NA	0.05069	1	0.059473	1
11P GAIN MUTATION ANALYSIS	17 (7%)	212	0.89172	1	0.02546	1	0.61326	1	0.88374	1	0.40908	1	0.80135	1
11Q GAIN MUTATION ANALYSIS	25 (11%)	204	0.48907	1	0.01848	1	0.83175	1	0.97264	1	0.49214	1	1	1
12P GAIN MUTATION ANALYSIS	16 (7%)	213	0.5297	1	0.14665	1	0.30741	1	0.076311	1	1	1	1	1
12Q GAIN MUTATION ANALYSIS	8 (3%)	221	0.058593	1	0.72125	1	1	1	0.076311	1	0.81509	1	0.48547	1
15Q GAIN MUTATION ANALYSIS	5 (2%)	224	0.47985	1	0.13992	1	0.38455	1	0.6659	1	0.61684	1	1	1
16P GAIN MUTATION ANALYSIS	7 (3%)	222	0.43338	1	0.13625	1	0.24652	1	NA	NA	0.42549	1	0.70712	1
16Q GAIN MUTATION ANALYSIS	9 (4%)	220	0.14933	1	0.15733	1	0.5165	1	0.77082	1	0.094598	1	0.74082	1
17P GAIN MUTATION ANALYSIS	5 (2%)	224	0.19758	1	0.49479	1	0.38455	1	0.70407	1	0.27786	1	0.079469	1
17Q GAIN MUTATION ANALYSIS	5 (2%)	224	0.19758	1	0.49479	1	0.38455	1	0.70407	1	0.27786	1	0.079469	1
18P GAIN MUTATION ANALYSIS	9 (4%)	220	0.31539	1	0.89995	1	1	1	0.076311	1	0.29058	1	0.48841	1
18Q GAIN MUTATION ANALYSIS	6 (3%)	223	0.04545	1	0.5019	1	1	1	NA	NA	0.44019	1	0.40749	1
19P GAIN MUTATION ANALYSIS	36 (16%)	193	0.41617	1	0.003436	1	1	1	0.79553	1	0.12723	1	1	1
19Q GAIN MUTATION ANALYSIS	11 (5%)	218	5.1038e-05	0.021	0.00058031	0.234	0.75849	1	0.24252	1	0.45453	1	0.34859	1
20P GAIN MUTATION ANALYSIS	22 (10%)	207	9.1876e-07	0.000382	8.2815e-05	0.034	0.17823	1	0.74613	1	0.35412	1	0.49978	1
20Q GAIN MUTATION ANALYSIS	22 (10%)	207	2.3412e-05	0.00969	0.00025028	0.102	0.071728	1	0.84095	1	0.51468	1	0.49978	1
21Q GAIN MUTATION ANALYSIS	10 (4%)	219	0.96553	1	0.48446	1	0.75468	1	NA	NA	0.10536	1	1	1
22Q GAIN MUTATION ANALYSIS	7 (3%)	222	0.29514	1	0.21158	1	0.70293	1	0.70407	1	0.061144	1	1	1
XQ GAIN MUTATION ANALYSIS	18 (8%)	211	0.55864	1	0.16458	1	0.081251	1	0.83563	1	0.23448	1	0.4514	1
1P LOSS MUTATION ANALYSIS	76 (33%)	153	0.067752	1	0.028514	1	1	1	0.64718	1	9.4237e-18	3.97e-15	0.061572	1
1Q LOSS MUTATION ANALYSIS	14 (6%)	215	0.72602	1	0.15226	1	0.40881	1	0.28939	1	0.046297	1	0.78409	1
2P LOSS MUTATION ANALYSIS	9 (4%)	220	0.13775	1	0.70064	1	0.30502	1	0.062461	1	0.4786	1	0.74082	1
2Q LOSS MUTATION ANALYSIS	7 (3%)	222	0.50123	1	0.007473	1	0.46576	1	0.16555	1	0.2672	1	1	1
3P LOSS MUTATION ANALYSIS	9 (4%)	220	0.12206	1	0.058366	1	0.30502	1	0.95792	1	0.91396	1	0.74082	1
3Q LOSS MUTATION ANALYSIS	15 (7%)	214	0.1066	1	0.83608	1	0.18472	1	0.27106	1	0.74849	1	1	1
4P LOSS MUTATION ANALYSIS	37 (16%)	192	0.73544	1	0.049356	1	0.27841	1	0.55365	1	0.091314	1	0.58742	1
4Q LOSS MUTATION ANALYSIS	46 (20%)	183	0.30553	1	0.42423	1	0.5072	1	0.60983	1	0.056572	1	0.86607	1
5P LOSS MUTATION ANALYSIS	19 (8%)	210	0.4973	1	0.097358	1	0.14662	1	0.36184	1	0.038007	1	0.046981	1
5Q LOSS MUTATION ANALYSIS	17 (7%)	212	0.1367	1	0.81902	1	0.80602	1	0.068651	1	0.56492	1	0.037183	1
6P LOSS MUTATION ANALYSIS	14 (6%)	215	0.021414	1	0.58624	1	0.78362	1	0.31944	1	0.025216	1	0.57396	1
6Q LOSS MUTATION ANALYSIS	29 (13%)	200	0.0038858	1	0.12445	1	0.11334	1	0.1657	1	0.0042249	1	0.31364	1
8P LOSS MUTATION ANALYSIS	8 (3%)	221	0.12409	1	0.11223	1	1	1	0.82421	1	0.2433	1	0.71503	1
8Q LOSS MUTATION ANALYSIS	6 (3%)	223	0.0047838	1	0.099695	1	0.41081	1	0.82421	1	0.21617	1	1	1
9P LOSS MUTATION ANALYSIS	55 (24%)	174	0.0098012	1	0.05296	1	0.53388	1	0.73988	1	0.10356	1	0.11292	1
9Q LOSS MUTATION ANALYSIS	22 (10%)	207	0.040313	1	0.040241	1	1	1	0.15768	1	0.47007	1	0.82243	1
10P LOSS MUTATION ANALYSIS	39 (17%)	190	1.1545e-12	4.84e-10	1.4294e-08	5.97e-06	0.021947	1	0.3047	1	0.00015621	0.0639	0.47341	1
10Q LOSS MUTATION ANALYSIS	47 (21%)	182	5.0284e-06	0.00209	2.2458e-07	9.36e-05	0.02203	1	0.64374	1	0.00029719	0.12	0.73799	1
11P LOSS MUTATION ANALYSIS	28 (12%)	201	0.45127	1	0.30821	1	0.16161	1	0.73122	1	0.0929	1	0.41668	1
11Q LOSS MUTATION ANALYSIS	9 (4%)	220	4.9443e-05	0.0204	0.15866	1	0.19194	1	0.43936	1	0.14001	1	0.48841	1
12P LOSS MUTATION ANALYSIS	13 (6%)	216	0.53926	1	0.19979	1	0.57093	1	0.3455	1	0.3333	1	1	1
12Q LOSS MUTATION ANALYSIS	21 (9%)	208	0.34801	1	0.30742	1	1	1	0.66717	1	0.30382	1	0.48403	1
13Q LOSS MUTATION ANALYSIS	59 (26%)	170	0.76876	1	0.24825	1	0.54448	1	0.3624	1	0.20027	1	0.088803	1
14Q LOSS MUTATION ANALYSIS	37 (16%)	192	0.0010308	0.414	0.020802	1	0.37297	1	0.1982	1	0.28869	1	0.71354	1
15Q LOSS MUTATION ANALYSIS	19 (8%)	210	0.46449	1	0.93142	1	0.63107	1	0.81121	1	0.83005	1	0.81002	1
16P LOSS MUTATION ANALYSIS	7 (3%)	222	0.40798	1	0.064706	1	1	1	0.43936	1	0.42549	1	0.43753	1
16Q LOSS MUTATION ANALYSIS	12 (5%)	217	0.27478	1	0.01948	1	0.3794	1	0.61885	1	0.36077	1	0.54638	1
17P LOSS MUTATION ANALYSIS	10 (4%)	219	0.00027552	0.112	0.00057234	0.231	0.11435	1	0.14233	1	0.84888	1	0.32259	1
17Q LOSS MUTATION ANALYSIS	7 (3%)	222	0.022784	1	0.018112	1	0.70293	1	0.31888	1	0.72064	1	0.70712	1
18P LOSS MUTATION ANALYSIS	27 (12%)	202	0.56268	1	0.70893	1	0.2251	1	0.54783	1	0.81337	1	0.67541	1
18Q LOSS MUTATION ANALYSIS	28 (12%)	201	0.3041	1	0.66303	1	0.68555	1	0.85174	1	0.56472	1	0.68473	1
19P LOSS MUTATION ANALYSIS	13 (6%)	216	0.88005	1	0.1974	1	0.77743	1	0.3515	1	0.93708	1	0.14113	1
19Q LOSS MUTATION ANALYSIS	87 (38%)	142	0.16137	1	0.18626	1	0.49465	1	0.88175	1	6.5591e-14	2.75e-11	0.40504	1
20P LOSS MUTATION ANALYSIS	3 (1%)	226	0.48527	1	0.54472	1	0.58686	1	NA	NA	1	1	1	1
21Q LOSS MUTATION ANALYSIS	19 (8%)	210	0.31819	1	0.42902	1	0.23775	1	0.25675	1	0.01926	1	0.62523	1
22Q LOSS MUTATION ANALYSIS	25 (11%)	204	0.046233	1	0.047772	1	0.017853	1	0.20836	1	0.019572	1	0.8297	1
XQ LOSS MUTATION ANALYSIS	31 (14%)	198	0.14093	1	0.41106	1	1	1	0.99834	1	0.29783	1	1	1