Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity -0.004 0.09 0.344 15.0 -9999.0 0.0 15.0 KIRREL -0.001 0.107 -9999.0 0.0 -0.453 14.0 14.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs 0.004 0.091 -9999.0 0.0 -0.345 15.0 15.0 PLCG1 0.025 0.005 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.026 0.002 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.021 0.011 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.034 0.077 -9999.0 0.0 -0.257 15.0 15.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.004 0.058 -9999.0 0.0 -0.241 11.0 11.0 FYN -0.006 0.071 0.269 3.0 -0.245 15.0 18.0 mol:Ca2+ 0.031 0.076 -9999.0 0.0 -0.255 15.0 15.0 mol:DAG 0.032 0.076 -9999.0 0.0 -0.256 15.0 15.0 NPHS2 0.003 0.026 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 0.032 0.076 -9999.0 0.0 -0.256 15.0 15.0 regulation of endocytosis 0.027 0.068 -9999.0 0.0 -0.232 15.0 15.0 Nephrin/NEPH1/podocin/Cholesterol 0.02 0.072 -9999.0 0.0 -0.255 15.0 15.0 establishment of cell polarity 0.004 0.09 -9999.0 0.0 -0.344 15.0 15.0 Nephrin/NEPH1/podocin/NCK1-2 0.045 0.075 -9999.0 0.0 -0.236 14.0 14.0 Nephrin/NEPH1/beta Arrestin2 0.028 0.069 -9999.0 0.0 -0.234 15.0 15.0 NPHS1 -0.002 0.066 -9999.0 0.0 -0.317 6.0 6.0 Nephrin/NEPH1/podocin 0.021 0.069 -9999.0 0.0 -0.246 15.0 15.0 TJP1 0.026 0.003 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.026 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.026 0.002 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.033 0.077 -9999.0 0.0 -0.257 15.0 15.0 CD2AP 0.026 0.002 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.033 0.075 -9999.0 0.0 -0.258 14.0 14.0 GRB2 0.026 0.005 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.01 0.081 0.281 4.0 -0.239 20.0 24.0 cytoskeleton organization -0.013 0.075 0.202 6.0 -0.276 11.0 17.0 Nephrin/NEPH1 0.013 0.064 -9999.0 0.0 -0.238 15.0 15.0 Nephrin/NEPH1/ZO-1 0.026 0.077 -9999.0 0.0 -0.274 15.0 15.0