Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.048 0.223 -9999.0 0.0 -0.464 50.0 50.0 MAP3K8 0.018 0.038 -9999.0 0.0 -0.177 7.0 7.0 FOS -0.049 0.199 -9999.0 0.0 -0.47 42.0 42.0 PRKCA 0.023 0.012 -9999.0 0.0 -9999.0 0.0 0.0 PTPN7 -0.064 0.166 -9999.0 0.0 -0.301 72.0 72.0 HRAS 0.024 0.007 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.012 0.103 -9999.0 0.0 -0.451 11.0 11.0 NRAS 0.022 0.01 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.036 0.024 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.037 0.17 -9999.0 0.0 -0.432 39.0 39.0 MAP2K1 0.007 0.108 -9999.0 0.0 -0.479 10.0 10.0 ELK1 0.023 0.014 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.005 0.089 -9999.0 0.0 -0.418 11.0 11.0 mol:GTP -0.0 0.001 -9999.0 0.0 -0.004 26.0 26.0 MAPK1 -0.048 0.189 -9999.0 0.0 -0.453 43.0 43.0 RAF1 -0.003 0.095 -9999.0 0.0 -0.437 11.0 11.0 KRAS 0.025 0.006 -9999.0 0.0 -9999.0 0.0 0.0