Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.043 0.202 -9999.0 0.0 -0.573 2.0 2.0 MAP3K8 0.008 0.092 -9999.0 0.0 -0.278 2.0 2.0 FOS -0.022 0.142 -9999.0 0.0 -0.443 2.0 2.0 PRKCA 0.026 0.022 -9999.0 0.0 -9999.0 0.0 0.0 PTPN7 0.017 0.039 -9999.0 0.0 -0.134 1.0 1.0 HRAS 0.031 0.013 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.004 0.007 -9999.0 0.0 -0.016 7.0 7.0 NRAS 0.029 0.015 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.04 0.032 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 0.016 0.097 -9999.0 0.0 -0.413 1.0 1.0 MAP2K1 0.017 0.062 -9999.0 0.0 -9999.0 0.0 0.0 ELK1 0.024 0.027 -9999.0 0.0 -9999.0 0.0 0.0 BRAF 0.008 0.02 -9999.0 0.0 -9999.0 0.0 0.0 mol:GTP -0.001 0.002 -9999.0 0.0 -0.004 8.0 8.0 MAPK1 -0.028 0.158 -9999.0 0.0 -0.5 2.0 2.0 RAF1 0.007 0.022 -9999.0 0.0 -9999.0 0.0 0.0 KRAS 0.031 0.013 -9999.0 0.0 -9999.0 0.0 0.0