Clinical Features MRNA_CNMF MRNA_CHIERARCHICAL CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nMutated (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q CDKN2A 26 (15%) 152 0.001414 0.239 0.048218 1 0.011867 1 0.66826 1 0.33991 1 0.20379 1 0.35277 1 0.6671 1 0.78289 1 1 1 1 1 0.099321 1 TP53 141 (79%) 37 0.044918 1 0.038034 1 4.1477e-05 0.00726 0.0014012 0.238 1 1 0.90185 1 0.00084139 0.144 0.013052 1 0.1356 1 0.51879 1 0.82375 1 0.72649 1 NFE2L2 27 (15%) 151 0.00023988 0.0415 0.00072991 0.126 0.019408 1 0.036488 1 0.25341 1 0.14367 1 3.2345e-06 0.000569 1.363e-06 0.000243 0.028858 1 1.748e-06 0.000309 0.58927 1 0.14 1 PIK3CA 27 (15%) 151 0.68982 1 0.59657 1 0.25767 1 0.54503 1 1 1 0.70924 1 0.36491 1 0.89146 1 0.61365 1 0.73862 1 0.45639 1 0.72649 1 PTEN 14 (8%) 164 0.3811 1 0.44798 1 0.22557 1 0.13405 1 0.72126 1 0.4734 1 0.63564 1 0.14551 1 0.57351 1 0.42976 1 0.35718 1 1 1 KEAP1 22 (12%) 156 0.0014959 0.251 0.00022872 0.0398 0.12192 1 0.075772 1 0.20419 1 0.096341 1 0.15903 1 0.043808 1 0.69946 1 0.82349 1 0.005042 0.842 0.60984 1 CSMD3 81 (46%) 97 0.32267 1 0.93117 1 0.73763 1 0.50821 1 0.2651 1 0.76919 1 0.52865 1 0.81576 1 0.66405 1 1 1 0.41907 1 0.16371 1 MLL2 36 (20%) 142 0.30056 1 0.92567 1 0.48473 1 0.31439 1 0.6964 1 0.2197 1 0.44159 1 0.62518 1 0.98598 1 0.59991 1 0.61383 1 1 1 FBXW7 11 (6%) 167 0.49313 1 0.94635 1 0.92497 1 NA NA 0.62139 1 0.78456 1 0.89884 1 0.71786 1 1 1 0.79674 1 NA NA 0.4902 1 RB1 12 (7%) 166 0.31354 1 0.18875 1 0.80654 1 0.10805 1 0.6571 1 0.43325 1 1 1 0.35387 1 0.57351 1 0.91064 1 NA NA 1 1 HS6ST1 5 (3%) 173 0.27649 1 0.29408 1 0.53799 1 NA NA NA NA NA NA 0.57177 1 0.07804 1 1 1 1 1 NA NA NA NA ZNF567 3 (2%) 175 NA NA NA NA 0.35777 1 NA NA 0.35868 1 0.42365 1 0.45018 1 0.42738 1 0.2502 1 0.18823 1 NA NA 1 1 ELTD1 18 (10%) 160 0.038189 1 0.32402 1 0.074357 1 0.5997 1 0.34058 1 0.6478 1 0.57775 1 0.43407 1 0.091608 1 0.7206 1 0.30453 1 0.41892 1 ASCL4 6 (3%) 172 0.096864 1 0.53361 1 1 1 0.78258 1 0.81655 1 0.83545 1 0.31835 1 0.24518 1 0.90926 1 0.21559 1 NA NA NA NA OR2G6 16 (9%) 162 0.38114 1 0.22983 1 0.8468 1 1 1 1 1 0.71709 1 0.18505 1 0.044576 1 0.40566 1 0.24422 1 0.66839 1 0.60984 1 NOTCH1 14 (8%) 164 0.8168 1 0.91964 1 0.46328 1 0.034203 1 0.59052 1 0.82385 1 0.67764 1 0.40724 1 0.18271 1 0.8434 1 0.4831 1 0.66795 1