Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.028 0.109 0.446 30.0 -9999.0 0.0 30.0 KIRREL -0.005 0.091 -9999.0 0.0 -0.753 7.0 7.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.028 0.11 -9999.0 0.0 -0.447 30.0 30.0 PLCG1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.022 0.084 -9999.0 0.0 -0.458 8.0 8.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.012 0.051 -9999.0 0.0 -0.341 7.0 7.0 FYN -0.02 0.08 -9999.0 0.0 -0.464 8.0 8.0 mol:Ca2+ -0.021 0.083 -9999.0 0.0 -0.454 8.0 8.0 mol:DAG -0.022 0.084 -9999.0 0.0 -0.456 8.0 8.0 NPHS2 -0.003 0.048 -9999.0 0.0 -0.58 3.0 3.0 mol:IP3 -0.022 0.084 -9999.0 0.0 -0.456 8.0 8.0 regulation of endocytosis -0.018 0.074 -9999.0 0.0 -0.432 8.0 8.0 Nephrin/NEPH1/podocin/Cholesterol -0.022 0.086 -9999.0 0.0 -0.465 8.0 8.0 establishment of cell polarity -0.028 0.109 -9999.0 0.0 -0.446 30.0 30.0 Nephrin/NEPH1/podocin/NCK1-2 -0.019 0.075 -9999.0 0.0 -0.417 8.0 8.0 Nephrin/NEPH1/beta Arrestin2 -0.019 0.075 -9999.0 0.0 -0.439 8.0 8.0 NPHS1 -0.021 0.122 -9999.0 0.0 -0.566 23.0 23.0 Nephrin/NEPH1/podocin -0.02 0.081 -9999.0 0.0 -0.466 8.0 8.0 TJP1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.022 0.084 -9999.0 0.0 -0.458 8.0 8.0 CD2AP 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.022 0.084 -9999.0 0.0 -0.458 8.0 8.0 GRB2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.02 0.131 -9999.0 0.0 -0.492 26.0 26.0 cytoskeleton organization -0.015 0.064 -9999.0 0.0 -0.416 8.0 8.0 Nephrin/NEPH1 -0.02 0.079 -9999.0 0.0 -0.32 30.0 30.0 Nephrin/NEPH1/ZO-1 -0.022 0.087 -9999.0 0.0 -0.458 8.0 8.0