Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.051 0.155 0.419 8.0 -0.326 108.0 116.0 MAP3K8 0.003 0.008 -9999.0 0.0 -9999.0 0.0 0.0 FOS -0.03 0.109 0.335 8.0 -0.297 34.0 42.0 PRKCA 0.001 0.045 0.224 7.0 -0.387 5.0 12.0 PTPN7 0.001 0.016 -9999.0 0.0 -9999.0 0.0 0.0 HRAS 0.003 0.006 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.002 0.009 0.049 8.0 -0.016 109.0 117.0 NRAS 0.098 0.108 0.222 245.0 -9999.0 0.0 245.0 RAS family/GTP 0.051 0.065 0.142 187.0 -9999.0 0.0 187.0 MAPK3 -0.038 0.137 0.225 8.0 -0.444 51.0 59.0 MAP2K1 0.01 0.056 0.2 11.0 -0.328 5.0 16.0 ELK1 0.0 0.015 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.002 0.039 0.291 2.0 -0.309 5.0 7.0 mol:GTP -0.001 0.003 0.008 8.0 -0.006 110.0 118.0 MAPK1 0.002 0.05 0.225 8.0 -0.382 1.0 9.0 RAF1 -0.002 0.038 0.289 1.0 -0.309 5.0 6.0 KRAS 0.027 0.068 0.222 62.0 -9999.0 0.0 62.0