Stabilization and expansion of the E-cadherin adherens junction
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
adherens junction organization	-0.015	0.073	-9999.0	0.0	-0.216	46.0	46.0
epithelial cell differentiation	0.051	0.045	-9999.0	0.0	-0.158	10.0	10.0
CYFIP2	0.026	0.038	-9999.0	0.0	-0.283	8.0	8.0
ENAH	-0.044	0.063	0.217	7.0	-9999.0	0.0	7.0
EGFR	0.002	0.091	-9999.0	0.0	-0.283	51.0	51.0
EPHA2	0.031	0.005	-9999.0	0.0	-9999.0	0.0	0.0
MYO6	-0.046	0.028	0.161	4.0	-0.272	1.0	5.0
CTNNB1	0.031	0.003	-9999.0	0.0	-9999.0	0.0	0.0
ABI1/Sra1/Nap1	0.055	0.033	-9999.0	0.0	-0.179	8.0	8.0
AQP5	-0.016	0.039	-9999.0	0.0	-0.303	4.0	4.0
CTNND1	0.031	0.003	-9999.0	0.0	-9999.0	0.0	0.0
mol:PI-4-5-P2	-0.043	0.027	0.159	4.0	-9999.0	0.0	4.0
regulation of calcium-dependent cell-cell adhesion	-0.044	0.031	0.159	4.0	-9999.0	0.0	4.0
EGF	0.029	0.008	-9999.0	0.0	-9999.0	0.0	0.0
NCKAP1	0.031	0.006	-9999.0	0.0	-9999.0	0.0	0.0
AQP3	-0.139	0.181	-9999.0	0.0	-0.406	170.0	170.0
cortical microtubule organization	0.051	0.045	-9999.0	0.0	-0.158	10.0	10.0
GO:0000145	-0.041	0.025	0.142	4.0	-9999.0	0.0	4.0
E-cadherin/Ca2+/beta catenin/alpha catenin/p120 catenin	0.056	0.047	-9999.0	0.0	-0.159	10.0	10.0
MLLT4	0.022	0.046	-9999.0	0.0	-0.283	12.0	12.0
ARF6/GDP	-0.061	0.033	-9999.0	0.0	-9999.0	0.0	0.0
ARF6	0.031	0.004	-9999.0	0.0	-9999.0	0.0	0.0
Ephrin A1/EPHA2/NCK1/GIT1	0.058	0.04	-9999.0	0.0	-9999.0	0.0	0.0
mol:Ca2+	-0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
VASP	-0.054	0.075	-9999.0	0.0	-0.244	60.0	60.0
PVRL2	0.029	0.015	-9999.0	0.0	-0.283	1.0	1.0
ZYX	-0.06	0.046	0.157	1.0	-0.272	1.0	2.0
ARF6/GTP	0.076	0.044	-9999.0	0.0	-9999.0	0.0	0.0
CDH1	0.023	0.04	-9999.0	0.0	-0.283	9.0	9.0
EGFR/EGFR/EGF/EGF	0.022	0.075	-9999.0	0.0	-0.168	56.0	56.0
RhoA/GDP	0.051	0.048	-9999.0	0.0	-0.159	11.0	11.0
actin cytoskeleton organization	-0.048	0.029	0.14	3.0	-0.273	1.0	4.0
IGF-1R heterotetramer	-0.033	0.125	-9999.0	0.0	-0.282	111.0	111.0
GIT1	0.03	0.007	-9999.0	0.0	-9999.0	0.0	0.0
IGF1R	-0.033	0.125	-9999.0	0.0	-0.283	111.0	111.0
IGF1	0.022	0.053	-9999.0	0.0	-0.283	16.0	16.0
DIAPH1	0.034	0.127	-9999.0	0.0	-0.544	22.0	22.0
Wnt receptor signaling pathway	-0.051	0.045	0.158	10.0	-9999.0	0.0	10.0
RHOA	0.031	0.014	-9999.0	0.0	-0.283	1.0	1.0
RhoA/GTP	-0.061	0.034	-9999.0	0.0	-9999.0	0.0	0.0
CTNNA1	0.03	0.014	-9999.0	0.0	-0.283	1.0	1.0
VCL	-0.049	0.029	0.141	3.0	-0.279	1.0	4.0
EFNA1	0.029	0.009	-9999.0	0.0	-9999.0	0.0	0.0
LPP	-0.05	0.039	0.144	3.0	-0.376	1.0	4.0
Ephrin A1/EPHA2	0.039	0.047	-9999.0	0.0	-0.164	8.0	8.0
SEC6/SEC8	-0.06	0.034	-9999.0	0.0	-0.275	1.0	1.0
MGAT3	-0.045	0.031	0.161	4.0	-9999.0	0.0	4.0
HGF/MET	0.022	0.072	-9999.0	0.0	-0.168	50.0	50.0
HGF	0.031	0.005	-9999.0	0.0	-9999.0	0.0	0.0
E-cadherin/Ca2+/beta catenin/alpha catenin/p120 catenin/EPLIN	-0.015	0.073	-9999.0	0.0	-0.218	46.0	46.0
actin cable formation	-0.028	0.088	0.276	13.0	-0.287	7.0	20.0
KIAA1543	-0.044	0.023	0.144	4.0	-9999.0	0.0	4.0
KIFC3	-0.045	0.024	0.162	2.0	-9999.0	0.0	2.0
NCK1	0.028	0.01	-9999.0	0.0	-9999.0	0.0	0.0
EXOC3	0.028	0.01	-9999.0	0.0	-9999.0	0.0	0.0
ACTN1	-0.047	0.029	0.161	4.0	-0.272	1.0	5.0
NCK1/GIT1	0.039	0.018	-9999.0	0.0	-9999.0	0.0	0.0
mol:GDP	0.051	0.045	-9999.0	0.0	-0.158	10.0	10.0
EXOC4	0.03	0.008	-9999.0	0.0	-9999.0	0.0	0.0
STX4	-0.046	0.025	0.161	4.0	-9999.0	0.0	4.0
PIP5K1C	-0.044	0.027	0.161	4.0	-9999.0	0.0	4.0
LIMA1	0.012	0.076	-9999.0	0.0	-0.283	35.0	35.0
ABI1	0.031	0.005	-9999.0	0.0	-9999.0	0.0	0.0
ROCK1	-0.04	0.078	0.245	12.0	-9999.0	0.0	12.0
adherens junction assembly	-0.059	0.1	0.227	1.0	-0.579	13.0	14.0
IGF-1R heterotetramer/IGF1	-0.007	0.096	-9999.0	0.0	-0.167	132.0	132.0
nectin-2(dimer)/I-afadin/I-afadin/nectin-2(dimer/I-afadin/I-afadin	0.035	0.04	-9999.0	0.0	-0.204	13.0	13.0
MET	0.004	0.084	-9999.0	0.0	-0.283	44.0	44.0
PLEKHA7	-0.046	0.025	0.161	4.0	-9999.0	0.0	4.0
mol:GTP	0.056	0.039	-9999.0	0.0	-9999.0	0.0	0.0
establishment of epithelial cell apical/basal polarity	-0.039	0.09	0.29	13.0	-0.273	1.0	14.0
cortical actin cytoskeleton stabilization	-0.015	0.073	-9999.0	0.0	-0.216	46.0	46.0
regulation of cell-cell adhesion	-0.048	0.029	0.14	3.0	-0.273	1.0	4.0
E-cadherin/Ca2+/beta catenin/alpha catenin/p120 catenin/EPLIN/cortical actin cytoskeleton	-0.015	0.073	-9999.0	0.0	-0.218	46.0	46.0