Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.03 0.151 -9999.0 0.0 -0.352 58.0 58.0 MAP3K8 0.019 0.026 -9999.0 0.0 -9999.0 0.0 0.0 FOS -0.013 0.125 0.478 8.0 -0.366 22.0 30.0 PRKCA 0.016 0.039 0.116 1.0 -0.285 4.0 5.0 PTPN7 0.018 0.035 0.165 7.0 -9999.0 0.0 7.0 HRAS 0.019 0.025 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.002 0.011 0.074 8.0 -0.023 2.0 10.0 NRAS 0.013 0.02 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.021 0.037 0.16 5.0 -9999.0 0.0 5.0 MAPK3 -0.015 0.146 0.339 8.0 -0.417 55.0 63.0 MAP2K1 0.014 0.07 0.272 9.0 -0.291 11.0 20.0 ELK1 0.016 0.033 -9999.0 0.0 -9999.0 0.0 0.0 BRAF 0.011 0.046 0.202 8.0 -0.247 8.0 16.0 mol:GTP -0.001 0.003 0.012 8.0 -0.005 106.0 114.0 MAPK1 0.004 0.116 0.339 8.0 -0.408 30.0 38.0 RAF1 0.011 0.051 0.202 8.0 -0.286 8.0 16.0 KRAS 0.017 0.023 -9999.0 0.0 -9999.0 0.0 0.0