Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.31 0.361 0.691 25.0 -9999.0 0.0 25.0 KIRREL -0.049 0.179 -9999.0 0.0 -0.964 2.0 2.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.311 0.362 -9999.0 0.0 -0.693 25.0 25.0 PLCG1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.265 0.318 -9999.0 0.0 -0.725 12.0 12.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.156 0.236 -9999.0 0.0 -0.693 5.0 5.0 FYN -0.233 0.31 -9999.0 0.0 -0.685 12.0 12.0 mol:Ca2+ -0.262 0.313 -9999.0 0.0 -0.714 12.0 12.0 mol:DAG -0.263 0.316 -9999.0 0.0 -0.72 12.0 12.0 NPHS2 -0.082 0.214 -9999.0 0.0 -0.84 4.0 4.0 mol:IP3 -0.263 0.316 -9999.0 0.0 -0.72 12.0 12.0 regulation of endocytosis -0.23 0.28 -9999.0 0.0 -0.881 5.0 5.0 Nephrin/NEPH1/podocin/Cholesterol -0.269 0.322 -9999.0 0.0 -0.58 26.0 26.0 establishment of cell polarity -0.31 0.361 -9999.0 0.0 -0.691 25.0 25.0 Nephrin/NEPH1/podocin/NCK1-2 -0.243 0.296 -9999.0 0.0 -0.931 5.0 5.0 Nephrin/NEPH1/beta Arrestin2 -0.234 0.286 -9999.0 0.0 -0.904 5.0 5.0 NPHS1 -0.369 0.427 -9999.0 0.0 -0.841 25.0 25.0 Nephrin/NEPH1/podocin -0.248 0.302 -9999.0 0.0 -0.692 12.0 12.0 TJP1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.265 0.318 -9999.0 0.0 -0.725 12.0 12.0 CD2AP 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.265 0.318 -9999.0 0.0 -0.725 12.0 12.0 GRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.23 0.31 -9999.0 0.0 -0.676 12.0 12.0 cytoskeleton organization -0.211 0.317 -9999.0 0.0 -0.705 12.0 12.0 Nephrin/NEPH1 -0.237 0.282 -9999.0 0.0 -0.529 25.0 25.0 Nephrin/NEPH1/ZO-1 -0.257 0.304 -9999.0 0.0 -0.574 25.0 25.0