Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.038 0.114 0.333 9.0 -9999.0 0.0 9.0 KIRREL -0.05 0.153 -9999.0 0.0 -0.404 11.0 11.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.039 0.114 -9999.0 0.0 -0.333 9.0 9.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.02 0.084 -9999.0 0.0 -0.235 9.0 9.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.013 0.079 -9999.0 0.0 -0.224 9.0 9.0 FYN -0.028 0.083 -9999.0 0.0 -0.218 11.0 11.0 mol:Ca2+ -0.021 0.083 -9999.0 0.0 -0.234 9.0 9.0 mol:DAG -0.021 0.084 -9999.0 0.0 -0.235 9.0 9.0 NPHS2 -0.01 0.032 -9999.0 0.0 -0.173 2.0 2.0 mol:IP3 -0.021 0.084 -9999.0 0.0 -0.235 9.0 9.0 regulation of endocytosis -0.018 0.079 -9999.0 0.0 -0.2 11.0 11.0 Nephrin/NEPH1/podocin/Cholesterol -0.028 0.083 -9999.0 0.0 -0.241 9.0 9.0 establishment of cell polarity -0.038 0.114 -9999.0 0.0 -0.333 9.0 9.0 Nephrin/NEPH1/podocin/NCK1-2 -0.011 0.078 -9999.0 0.0 -0.209 9.0 9.0 Nephrin/NEPH1/beta Arrestin2 -0.017 0.08 -9999.0 0.0 -0.202 11.0 11.0 NPHS1 -0.011 0.045 -9999.0 0.0 -0.186 4.0 4.0 Nephrin/NEPH1/podocin -0.027 0.083 -9999.0 0.0 -0.219 11.0 11.0 TJP1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.02 0.084 -9999.0 0.0 -0.235 9.0 9.0 CD2AP 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.02 0.084 -9999.0 0.0 -0.235 9.0 9.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.049 0.107 -9999.0 0.0 -0.259 13.0 13.0 cytoskeleton organization -0.013 0.085 -9999.0 0.0 -0.239 9.0 9.0 Nephrin/NEPH1 -0.024 0.079 -9999.0 0.0 -0.23 9.0 9.0 Nephrin/NEPH1/ZO-1 -0.021 0.091 -9999.0 0.0 -0.256 9.0 9.0