Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 0.03 0.12 0.241 1.0 -0.335 5.0 6.0 MAP3K8 0.004 0.088 -9999.0 0.0 -0.324 5.0 5.0 FOS 0.017 0.111 0.215 1.0 -0.363 4.0 5.0 PRKCA 0.027 0.012 -9999.0 0.0 -9999.0 0.0 0.0 PTPN7 0.017 0.058 -9999.0 0.0 -0.324 2.0 2.0 HRAS 0.029 0.006 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB 0.018 0.058 -9999.0 0.0 -0.324 2.0 2.0 NRAS 0.029 0.003 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.053 0.019 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 0.01 0.111 -9999.0 0.0 -0.415 4.0 4.0 MAP2K1 0.007 0.086 -9999.0 0.0 -0.386 2.0 2.0 ELK1 0.028 0.012 -9999.0 0.0 -9999.0 0.0 0.0 BRAF 0.01 0.062 -9999.0 0.0 -0.281 3.0 3.0 mol:GTP 0.0 0.001 0.002 3.0 -0.004 2.0 5.0 MAPK1 0.015 0.101 -9999.0 0.0 -0.413 3.0 3.0 RAF1 0.012 0.056 -9999.0 0.0 -0.311 2.0 2.0 KRAS 0.029 0.005 -9999.0 0.0 -9999.0 0.0 0.0