Molecular subtypes CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nCNV (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Chi-square test_P Chi-square test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Amp Peak 1(1p36.22) 0 (0%) 269 5.2294e-08 3.43e-05 0.0030392 1 0.63746 1 0.08809 1 0.00085354 0.4 0.0088677 1 0.9747 1 0.024901 1 0.75755 1 0.024694 1 Amp Peak 2(1q21.3) 0 (0%) 197 1.9929e-18 1.47e-15 4.3167e-11 3.01e-08 0.048082 1 0.0092327 1 3.1434e-12 2.22e-09 4.743e-07 0.000303 9.5421e-09 6.39e-06 3.0866e-08 2.04e-05 0.00034663 0.174 6.3947e-10 4.37e-07 Amp Peak 3(1q42.3) 0 (0%) 200 3.533e-14 2.55e-11 1.152e-07 7.49e-05 0.31646 1 0.3103 1 4.2107e-09 2.85e-06 0.00017169 0.0905 1.9341e-08 1.29e-05 6.6079e-09 4.45e-06 0.017753 1 7.2773e-08 4.75e-05 Amp Peak 4(3q26.2) 0 (0%) 204 6.7818e-05 0.038 0.0074335 1 0.97196 1 0.098623 1 0.36879 1 0.32495 1 0.42452 1 0.14559 1 0.31937 1 0.0041845 1 Amp Peak 5(5p13.1) 0 (0%) 218 7.4819e-14 5.39e-11 2.0918e-07 0.000135 0.7759 1 1 1 2.5193e-08 1.67e-05 0.00016085 0.0856 0.00034682 0.174 1.9916e-06 0.00124 0.033418 1 5.8362e-06 0.00357 Amp Peak 6(6p21.1) 0 (0%) 225 2.8446e-16 2.09e-13 2.191e-10 1.51e-07 0.14693 1 0.45031 1 0.00023253 0.12 0.0087075 1 6.0502e-05 0.0341 1.3049e-06 0.000823 0.053477 1 4.9647e-06 0.00305 Amp Peak 7(6q12) 0 (0%) 245 1.3689e-09 9.29e-07 2.3067e-08 1.53e-05 0.02412 1 0.14497 1 4.1778e-06 0.00259 0.00011824 0.0642 0.00086375 0.404 5.1487e-05 0.0292 0.058098 1 4.6299e-06 0.00285 Amp Peak 8(6q21) 0 (0%) 249 3.8965e-08 2.56e-05 1.68e-05 0.00988 0.23592 1 0.42539 1 2.7431e-05 0.0159 1.1091e-05 0.00659 0.0035687 1 0.0010047 0.463 0.037121 1 1.5633e-05 0.00922 Amp Peak 9(7p22.3) 0 (0%) 148 1.4088e-18 1.04e-15 1.739e-05 0.0102 0.36981 1 0.90842 1 0.0015181 0.676 0.030639 1 0.012591 1 0.0012262 0.558 0.0040793 1 0.00023339 0.12 Amp Peak 10(7p11.2) 0 (0%) 162 5.3293e-16 3.91e-13 0.0099491 1 0.82784 1 0.92069 1 0.11068 1 0.44836 1 0.022133 1 0.031477 1 0.0178 1 0.043743 1 Amp Peak 11(7q21.2) 0 (0%) 168 3.0732e-15 2.25e-12 0.019553 1 0.21082 1 0.6248 1 0.36598 1 0.40974 1 0.29899 1 0.17417 1 0.28682 1 0.083876 1 Amp Peak 12(8p23.1) 0 (0%) 184 0.00086243 0.404 0.0029823 1 0.61122 1 0.71615 1 0.028344 1 0.002379 1 0.30385 1 0.022481 1 0.16129 1 0.039297 1 Amp Peak 13(8q24.21) 0 (0%) 101 0.00062619 0.299 4.4627e-05 0.0254 0.37738 1 0.62395 1 0.0093106 1 0.11642 1 0.0012811 0.58 0.0001809 0.0952 0.00013965 0.0753 0.00025402 0.129 Amp Peak 14(9p24.1) 0 (0%) 256 0.58199 1 0.08784 1 0.61456 1 0.014755 1 0.089336 1 0.047331 1 0.18766 1 0.013871 1 0.029856 1 0.12953 1 Amp Peak 15(9q34.3) 0 (0%) 231 2.1162e-06 0.00132 0.0051731 1 0.67091 1 0.17547 1 0.021415 1 0.010251 1 0.21468 1 0.080996 1 0.032103 1 0.014282 1 Amp Peak 16(10q22.2) 0 (0%) 249 6.2532e-06 0.0038 0.074625 1 0.036627 1 0.20435 1 0.011635 1 0.0082492 1 0.10477 1 0.048685 1 0.17334 1 0.043803 1 Amp Peak 17(10q26.13) 0 (0%) 244 0.00036067 0.18 0.0012812 0.58 0.051128 1 0.25601 1 0.002894 1 0.0035959 1 0.4443 1 0.0091882 1 0.89491 1 0.0158 1 Amp Peak 18(11p13) 0 (0%) 251 0.0022972 0.992 0.1863 1 0.67399 1 0.45083 1 0.00098773 0.457 0.00045607 0.222 0.049334 1 2.4826e-05 0.0145 0.27526 1 0.0054027 1 Amp Peak 19(11q13.3) 0 (0%) 237 7.1667e-06 0.00434 0.19377 1 0.19384 1 0.71767 1 0.1052 1 0.012903 1 0.00059009 0.283 0.043693 1 0.012908 1 0.053854 1 Amp Peak 20(12p12.1) 0 (0%) 219 6.1203e-05 0.0344 0.011401 1 0.34139 1 0.087249 1 0.29785 1 0.43943 1 0.016655 1 0.10087 1 0.013121 1 0.087687 1 Amp Peak 21(12q15) 0 (0%) 228 0.00016179 0.0858 0.00048876 0.237 0.13298 1 0.62772 1 0.10661 1 0.017747 1 0.14481 1 0.06732 1 0.10953 1 0.05513 1 Amp Peak 22(13q12.3) 0 (0%) 189 2.4291e-10 1.67e-07 4.545e-06 0.0028 0.26234 1 0.4279 1 0.0078204 1 0.3751 1 0.0096856 1 0.0068257 1 0.059577 1 0.0091785 1 Amp Peak 23(13q22.1) 0 (0%) 184 1.0558e-07 6.87e-05 4.1325e-05 0.0238 0.094752 1 0.28826 1 0.00029054 0.147 0.0017067 0.753 0.0036289 1 4.5972e-05 0.0262 0.0047421 1 3.7944e-05 0.0219 Amp Peak 24(15q26.1) 0 (0%) 236 1.239e-12 8.86e-10 0.00044114 0.216 0.35363 1 0.76444 1 6.6093e-05 0.0371 2.4145e-05 0.0141 0.063296 1 0.020201 1 0.0085473 1 0.093815 1 Amp Peak 25(17q12) 0 (0%) 213 1.1193e-14 8.13e-12 2.6762e-06 0.00166 0.73419 1 0.53486 1 0.00015799 0.0844 0.00022007 0.114 0.00035296 0.176 0.00016305 0.0861 0.17125 1 0.00227 0.983 Amp Peak 26(18q11.2) 0 (0%) 215 1.7492e-07 0.000113 0.00030593 0.154 0.30593 1 0.03639 1 0.0066604 1 0.014749 1 0.038639 1 0.013479 1 0.032228 1 0.042317 1 Amp Peak 27(19q12) 0 (0%) 215 1.0641e-15 7.79e-13 1.0052e-10 6.96e-08 0.0031971 1 0.015746 1 1.0132e-13 7.29e-11 5.6184e-09 3.79e-06 4.397e-06 0.00272 2.0996e-14 1.52e-11 0.1726 1 7.0496e-13 5.05e-10 Amp Peak 28(20q13.2) 0 (0%) 104 2.4049e-24 1.8e-21 4.2366e-12 2.99e-09 0.0049943 1 0.7389 1 4.2455e-08 2.79e-05 1.7681e-05 0.0104 1.28e-06 0.000809 4.398e-12 3.1e-09 0.063964 1 1.7909e-09 1.21e-06 Amp Peak 29(Xq27.3) 0 (0%) 245 2.1844e-05 0.0128 0.19077 1 0.98039 1 0.63291 1 0.055038 1 0.64601 1 0.055338 1 0.93203 1 0.071486 1 0.22756 1 Del Peak 1(1p36.11) 0 (0%) 222 9.6242e-15 7.02e-12 0.0003959 0.194 0.19064 1 0.043589 1 0.00011331 0.0619 0.00096231 0.447 7.8733e-05 0.0439 7.8373e-05 0.0437 0.0067025 1 0.00034049 0.171 Del Peak 2(1p13.2) 0 (0%) 246 4.7354e-13 3.4e-10 0.0066913 1 0.12843 1 0.16857 1 0.00014661 0.0787 0.00057484 0.276 0.0034746 1 0.0114 1 0.40448 1 0.027184 1 Del Peak 3(1q44) 0 (0%) 282 0.014532 1 0.0074751 1 0.61803 1 0.20698 1 0.17008 1 0.012945 1 0.16639 1 0.13266 1 0.050222 1 0.085291 1 Del Peak 4(2q32.1) 0 (0%) 263 0.00029095 0.147 0.10796 1 0.49 1 0.22075 1 0.086031 1 0.83008 1 0.40275 1 0.032974 1 0.61732 1 0.51457 1 Del Peak 5(2q37.2) 0 (0%) 258 0.00020175 0.105 0.0073601 1 0.25867 1 0.28436 1 0.0068488 1 0.38857 1 0.010895 1 1.562e-06 0.000979 0.15828 1 0.00039023 0.192 Del Peak 6(3p26.2) 0 (0%) 222 7.1298e-12 5.01e-09 5.7426e-05 0.0324 0.2008 1 0.98247 1 0.0015057 0.672 0.011191 1 0.00045322 0.221 0.00023837 0.122 0.083316 1 0.0025715 1 Del Peak 7(3p14.2) 0 (0%) 203 6.1432e-11 4.26e-08 1.2366e-06 0.000783 0.44179 1 0.95315 1 0.0002418 0.124 0.00023049 0.119 0.00036326 0.181 4.3498e-05 0.0249 0.061282 1 6.0752e-06 0.00371 Del Peak 8(3q26.31) 0 (0%) 271 9.8882e-06 0.0059 0.00010717 0.0586 0.1932 1 0.71108 1 0.0013581 0.611 0.0068031 1 0.00078825 0.372 0.0063204 1 0.16588 1 0.01543 1 Del Peak 9(4p16.3) 0 (0%) 193 6.3033e-12 4.44e-09 0.00099107 0.458 0.46518 1 0.22679 1 0.00012621 0.0683 0.00020655 0.108 0.0001827 0.0959 1.1021e-06 0.000699 0.0022388 0.976 6.0883e-06 0.00371 Del Peak 10(4q22.1) 0 (0%) 170 6.4057e-19 4.76e-16 3.8453e-07 0.000247 0.14434 1 0.76701 1 0.0025777 1 0.00090667 0.422 0.011295 1 4.1403e-05 0.0238 0.10293 1 0.0045199 1 Del Peak 11(4q34.3) 0 (0%) 178 1.071e-14 7.79e-12 1.8722e-06 0.00117 0.074817 1 0.88135 1 4.2454e-05 0.0243 4.3798e-05 0.025 5.2862e-05 0.03 8.1596e-07 0.00052 0.1411 1 9.1934e-05 0.0507 Del Peak 12(5q11.2) 0 (0%) 202 5.9433e-27 4.45e-24 2.4868e-14 1.8e-11 0.30839 1 0.43805 1 2.8066e-11 1.96e-08 1.4983e-10 1.03e-07 2.766e-09 1.87e-06 6.5458e-12 4.6e-09 2.9949e-06 0.00186 1.0297e-12 7.37e-10 Del Peak 13(5q23.2) 0 (0%) 212 1.4369e-22 1.07e-19 2.2928e-12 1.63e-09 0.17501 1 0.23786 1 1.687e-12 1.2e-09 5.0972e-09 3.44e-06 2.3997e-10 1.65e-07 5.2895e-11 3.69e-08 8.1736e-07 0.00052 1.4522e-12 1.04e-09 Del Peak 14(6p25.3) 0 (0%) 237 2.4044e-07 0.000155 0.00057609 0.277 0.46645 1 0.20547 1 0.0016344 0.724 0.0012363 0.561 0.010438 1 6.1117e-06 0.00372 0.10352 1 0.010548 1 Del Peak 15(6q26) 0 (0%) 243 7.2407e-06 0.00437 0.071103 1 0.5912 1 0.090092 1 0.0012159 0.554 0.00039426 0.194 0.27922 1 0.016897 1 0.18723 1 0.090796 1 Del Peak 16(7q31.1) 0 (0%) 261 2.7477e-07 0.000177 0.0011647 0.533 0.48252 1 0.78031 1 0.026616 1 0.086904 1 0.01679 1 0.067681 1 9.8666e-05 0.0543 0.045024 1 Del Peak 17(7q36.3) 0 (0%) 247 1.0511e-14 7.65e-12 1.3075e-05 0.00775 0.39207 1 0.80155 1 2.4406e-06 0.00152 1.363e-05 0.00807 0.012365 1 7.1143e-05 0.0398 0.038331 1 0.0001051 0.0576 Del Peak 18(8p23.2) 0 (0%) 228 5.1709e-15 3.77e-12 8.1061e-06 0.00487 0.10514 1 0.14603 1 8.1418e-06 0.00489 9.9202e-06 0.00591 0.0050385 1 7.9631e-08 5.19e-05 0.024374 1 0.0002143 0.111 Del Peak 19(9p23) 0 (0%) 185 3.4142e-18 2.52e-15 8.7608e-05 0.0484 0.04766 1 0.51161 1 9.8462e-06 0.00589 0.0023061 0.994 0.032533 1 0.0045278 1 0.85223 1 0.0020418 0.894 Del Peak 20(9p21.3) 0 (0%) 187 9.2337e-19 6.85e-16 1.9238e-10 1.33e-07 0.00012283 0.0666 0.15296 1 1.6995e-08 1.14e-05 0.00011669 0.0635 0.027266 1 0.0013928 0.624 0.86371 1 0.00015939 0.085 Del Peak 21(9q21.11) 0 (0%) 232 2.5152e-12 1.79e-09 0.00022338 0.115 0.16339 1 0.52779 1 0.014316 1 0.14759 1 0.022493 1 0.012362 1 0.46519 1 0.0011579 0.531 Del Peak 22(10p15.1) 0 (0%) 267 0.00011501 0.0627 0.27709 1 0.41175 1 0.61551 1 0.24387 1 0.23422 1 0.13201 1 0.042315 1 0.15425 1 0.40551 1 Del Peak 23(10q22.3) 0 (0%) 256 4.6144e-10 3.16e-07 0.0007179 0.34 0.74942 1 0.45288 1 0.00018533 0.0971 0.0094773 1 0.011455 1 0.00067749 0.323 0.11671 1 0.011055 1 Del Peak 24(10q23.31) 0 (0%) 232 3.0104e-12 2.13e-09 5.2253e-06 0.0032 0.068969 1 0.15913 1 3.2712e-06 0.00203 0.0029698 1 0.00037362 0.185 1.0733e-05 0.00639 0.25038 1 0.00050054 0.242 Del Peak 25(11p15.4) 0 (0%) 246 2.1477e-08 1.43e-05 8.053e-06 0.00485 1.5724e-05 0.00926 0.0011844 0.541 0.0045639 1 0.00084224 0.396 0.49176 1 8.2888e-05 0.0461 0.25575 1 0.0059877 1 Del Peak 26(11q23.2) 0 (0%) 243 0.00068998 0.328 0.001666 0.736 0.7911 1 0.51305 1 0.0070652 1 0.23288 1 0.3256 1 0.53783 1 0.4206 1 0.62228 1 Del Peak 27(12p13.31) 0 (0%) 255 9.8709e-12 6.92e-09 5.6975e-06 0.00349 0.60924 1 0.93175 1 1.4927e-07 9.69e-05 1.3561e-06 0.000854 0.032407 1 0.011197 1 0.23875 1 5.5158e-05 0.0312 Del Peak 28(13q12.11) 0 (0%) 261 9.8372e-05 0.0542 0.12644 1 0.43546 1 0.081981 1 0.25902 1 0.02952 1 0.50885 1 0.072931 1 0.86833 1 0.049509 1 Del Peak 29(14q21.1) 0 (0%) 234 9.4949e-09 6.37e-06 0.015925 1 0.18083 1 0.47949 1 0.00015676 0.084 0.0001887 0.0987 0.004903 1 0.00053298 0.257 0.58244 1 0.00039038 0.192 Del Peak 30(14q32.33) 0 (0%) 216 1.2402e-09 8.43e-07 0.042169 1 0.87629 1 0.58897 1 0.00037737 0.186 1.3841e-05 0.00818 0.034377 1 0.10023 1 0.10816 1 0.011594 1 Del Peak 31(15q15.1) 0 (0%) 226 1.7427e-13 1.25e-10 2.1075e-07 0.000136 0.0054845 1 0.0066871 1 7.1514e-08 4.68e-05 2.6639e-08 1.76e-05 6.4437e-06 0.0039 1.8363e-08 1.22e-05 0.00045523 0.222 4.0851e-05 0.0236 Del Peak 32(16p13.3) 0 (0%) 247 5.9968e-11 4.17e-08 4.1382e-05 0.0238 0.58968 1 0.8376 1 3.4394e-08 2.27e-05 1.1101e-09 7.56e-07 0.00014355 0.0772 4.9673e-06 0.00305 0.00015705 0.084 5.4099e-07 0.000345 Del Peak 33(16q23.1) 0 (0%) 187 4.292e-08 2.82e-05 0.0028933 1 0.68286 1 0.24334 1 0.0013673 0.614 2.8979e-05 0.0168 0.010562 1 0.0020991 0.917 0.0022438 0.976 0.0053898 1 Del Peak 34(17p12) 0 (0%) 190 3.0887e-29 2.32e-26 3.2797e-11 2.29e-08 0.38692 1 0.4279 1 3.2942e-08 2.17e-05 4.3295e-07 0.000278 5.566e-05 0.0314 1.6551e-07 0.000107 0.0010158 0.467 1.3762e-08 9.21e-06 Del Peak 35(17q24.3) 0 (0%) 250 1.4355e-10 9.92e-08 0.00025131 0.128 0.39937 1 0.35702 1 0.00086376 0.404 0.0080579 1 0.002347 1 0.00080854 0.381 0.076944 1 0.098671 1 Del Peak 36(18q21.2) 0 (0%) 172 3.4356e-14 2.48e-11 0.0025647 1 0.7356 1 0.93259 1 0.00056875 0.274 0.0019626 0.862 0.013596 1 0.0030395 1 0.14828 1 0.01456 1 Del Peak 37(19p13.3) 0 (0%) 206 5.4162e-29 4.06e-26 2.3307e-16 1.72e-13 0.0022387 0.976 0.23756 1 1.2286e-16 9.05e-14 3.3824e-16 2.48e-13 4.7125e-07 0.000302 2.8487e-21 2.12e-18 0.0014286 0.639 2.2109e-19 1.64e-16 Del Peak 38(19q13.11) 0 (0%) 262 3.8824e-10 2.66e-07 8.4859e-05 0.0471 0.13407 1 0.76295 1 0.00025746 0.131 0.0068328 1 0.0013416 0.605 1.4746e-06 0.000926 0.0058976 1 8.4997e-05 0.0471 Del Peak 39(20p12.1) 0 (0%) 253 2.8565e-12 2.03e-09 0.00070056 0.333 0.73579 1 0.65996 1 0.013034 1 0.015806 1 0.00016163 0.0858 0.0091606 1 0.23301 1 0.014289 1 Del Peak 40(20p12.1) 0 (0%) 253 2.8565e-12 2.03e-09 0.00070056 0.333 0.73579 1 0.65996 1 0.013034 1 0.015806 1 0.00016163 0.0858 0.0091606 1 0.23301 1 0.014289 1 Del Peak 41(21q11.2) 0 (0%) 198 5.8849e-11 4.1e-08 2.7064e-05 0.0158 0.28233 1 0.17204 1 0.00028278 0.143 8.1764e-07 0.00052 0.00021079 0.11 0.021266 1 0.076724 1 0.001909 0.84 Del Peak 42(21q22.13) 0 (0%) 191 9.3064e-11 6.45e-08 0.00036168 0.18 0.075365 1 0.3519 1 0.0023412 1 8.7838e-06 0.00526 0.0075628 1 0.0085952 1 0.099285 1 0.0050044 1 Del Peak 43(22q13.31) 0 (0%) 204 1.6477e-17 1.22e-14 0.00013549 0.0732 0.082996 1 0.40029 1 0.00024488 0.125 0.0037249 1 9.9848e-05 0.0548 1.3763e-06 0.000866 0.07541 1 3.5188e-05 0.0204 Del Peak 44(Xp22.2) 0 (0%) 244 1.0438e-09 7.12e-07 0.0016225 0.72 0.39069 1 0.61689 1 0.0032637 1 0.028794 1 0.14335 1 0.00037508 0.186 0.67571 1 0.0072838 1 Del Peak 45(Xp21.1) 0 (0%) 253 6.9857e-09 4.69e-06 0.0040678 1 0.048256 1 0.91314 1 0.090416 1 0.012976 1 0.68304 1 0.095235 1 0.97567 1 0.11252 1 Del Peak 46(Xq21.33) 0 (0%) 263 7.285e-06 0.00439 0.035216 1 0.73131 1 0.32864 1 0.029275 1 0.0028352 1 0.10561 1 0.025344 1 0.48197 1 0.023175 1